Identification
Name: S-formylglutathione hydrolase yeiG
Synonyms:
  • FGH
Gene Name: yeiG
Enzyme Class:
Biological Properties
General Function: Involved in carboxylesterase activity
Specific Function: Serine hydrolase involved in the detoxification of formaldehyde. Hydrolyzes S-formylglutathione to glutathione and formate. Shows also esterase activity against alpha-naphthyl acetate, lactoylglutathione, palmitoyl-CoA and several pNP-esters of short chain fatty acids
Cellular Location: Cytoplasmic
KEGG Pathways:
KEGG Reactions:
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SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
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Complex Reactions:
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Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000053Formic acidMetaboCard
PAMDB000048GlutathioneMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB000417S-FormylglutathioneMetaboCard
PAMDB000142WaterMetaboCard
GO Classification:
Component
cytoplasmic membrane-bounded vesicle
cytoplasmic vesicle
organelle
vesicle
Function
carboxylesterase activity
catalytic activity
hydrolase activity
hydrolase activity, acting on ester bonds
S-formylglutathione hydrolase activity
thiolester hydrolase activity
Gene Properties
Locus tag: PA3628
Strand: -
Entrez Gene ID: 880458
Accession: NP_252318.1
GI: 15598824
Sequence start: 4062970
Sequence End: 4063821
Sequence Length: 851
Gene Sequence:
>PA3628
GTGAAGGATTCCCTCGAACTGATCGGCAGCCAGAAGACCTTCGGCGGCTGGCACCAGCGTTACCGTCATTTTTCCCGGACCCTGAACTGCGAGATGGTCTTCGCCATCTACCTGCCGCCCCAGGCCGAGCCGGAGGCGGCGCTGCCGGCCCTGTACTGGCTGTCCGGGCTGACCTGTACCGACGAGAACTTCATGCAGAAGGCCGGCGCCCAGCGGGTCGCCGCCGAACTGGGATTGGTACTGGTGGCGCCGGATACCAGCCCGCGCGGCAGCGGTGTCCCCGGCGATCCCGACGGCGCCTGGGACTTCGGCCTGGGCGCAGGCTTCTACCTGAACGCCACGCAGGAGCCCTGGGCCGCGCACTACCGCATGCACGACTACGTGGTGCACGAGTTGCCGGCGCTGATCGAGGCGCATTTCCCGGTGTCCCGGCGGCGCGGCATCAGCGGGCACTCGATGGGTGGGCATGGCGCGCTGGTTTGCGCGCTGCGCAACCCGGGGCGCTACCTGTCGCTGTCGGCCTTCGCGCCGATCTGCCATCCGAGCGATTGTCCCTGGGGCCAGAAGGCGTTCTCCCGCTACCTGGGCGAGGACCCGGCGGCCTGGCGCGAGTGGGATGCCTGTGCGTTGCTCGAGGGTGCGTCCGAACGCTTGCCGATCCTGGTCGACCAGGGCGAGCGCGACGACTTCCTCGCCGTCCAGCTCAAGCCGGAAGCGCTACGCAATGCGGCGGACAAGGCCGGCCACCCGCTGGAGCTGCGTCTGCAACCAGGTTACGACCACAGCTACTACTTCATCGCCAGTTTCATCGAGGATCACCTGCGCCATCATGCCGGGGTTCTCAACGGTTGA
Protein Properties
Protein Residues: 283
Protein Molecular Weight: 31.2 kDa
Protein Theoretical pI: 6.26
Hydropathicity (GRAVY score): -0.253
Charge at pH 7 (predicted): -5.82
Protein Sequence:
>PA3628
MKDSLELIGSQKTFGGWHQRYRHFSRTLNCEMVFAIYLPPQAEPEAALPALYWLSGLTCTDENFMQKAGAQRVAAELGLVLVAPDTSPRGSGVPGDPDGAWDFGLGAGFYLNATQEPWAAHYRMHDYVVHELPALIEAHFPVSRRRGISGHSMGGHGALVCALRNPGRYLSLSAFAPICHPSDCPWGQKAFSRYLGEDPAAWREWDACALLEGASERLPILVDQGERDDFLAVQLKPEALRNAADKAGHPLELRLQPGYDHSYYFIASFIEDHLRHHAGVLNG
References
External Links:
Resource Link
Genome ID: PA3628
Entrez Gene ID: 880458
NCBI Protein ID: 15598824
General Reference: PaperBLAST - Find papers about PA3628 and its homologs