Identification
Name: 3-oxoacyl-[acyl-carrier-protein] synthase 1
Synonyms:
  • 3-oxoacyl-[acyl-carrier-protein] synthase I
  • Beta-ketoacyl-ACP synthase I
  • KAS I
Gene Name: fabB
Enzyme Class:
Biological Properties
General Function: Involved in catalytic activity
Specific Function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Specific for elongation from C-10 to unsaturated C-16 and C-18 fatty acids
Cellular Location: Cytoplasm
KEGG Pathways:
KEGG Reactions:
Acetyl-[acyl-carrier protein]+Malonyl-[acyl-carrier protein]Acetoacetyl-[acp]+Thumb+Acyl-carrier protein
Acetyl-[acyl-carrier protein] + Malonyl-[acyl-carrier protein] ↔ Acetoacetyl-[acp] + Carbon dioxide + Acyl-carrier protein
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Dodecanoyl-[acyl-carrier protein]+Malonyl-[acyl-carrier protein]3-Oxotetradecanoyl-[acp]+Thumb+Acyl-carrier protein
Dodecanoyl-[acyl-carrier protein] + Malonyl-[acyl-carrier protein] ↔ 3-Oxotetradecanoyl-[acp] + Carbon dioxide + Acyl-carrier protein
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Butyryl-[acp]+Malonyl-[acyl-carrier protein]3-Oxohexanoyl-[acp]+Thumb+Acyl-carrier protein
Butyryl-[acp] + Malonyl-[acyl-carrier protein] ↔ 3-Oxohexanoyl-[acp] + Carbon dioxide + Acyl-carrier protein
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Hexanoyl-[acp]+Malonyl-[acyl-carrier protein]3-Oxooctanoyl-[acp]+Thumb+Acyl-carrier protein
Hexanoyl-[acp] + Malonyl-[acyl-carrier protein] ↔ 3-Oxooctanoyl-[acp] + Carbon dioxide + Acyl-carrier protein
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Octanoyl-[acp]+Malonyl-[acyl-carrier protein]3-Oxodecanoyl-[acp]+Thumb+Acyl-carrier protein
Octanoyl-[acp] + Malonyl-[acyl-carrier protein] ↔ 3-Oxodecanoyl-[acp] + Carbon dioxide + Acyl-carrier protein
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Decanoyl-[acp]+Malonyl-[acyl-carrier protein]3-Oxododecanoyl-[acp]+Thumb+Acyl-carrier protein
Decanoyl-[acp] + Malonyl-[acyl-carrier protein] ↔ 3-Oxododecanoyl-[acp] + Carbon dioxide + Acyl-carrier protein
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Tetradecanoyl-[acp]+Malonyl-[acyl-carrier protein]3-Oxohexadecanoyl-[acp]+Thumb+Acyl-carrier protein
Tetradecanoyl-[acp] + Malonyl-[acyl-carrier protein] ↔ 3-Oxohexadecanoyl-[acp] + Carbon dioxide + Acyl-carrier protein
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Hexadecanoyl-[acp]+Malonyl-[acyl-carrier protein]3-Oxostearoyl-[acp]+Acyl-carrier protein+Thumb
Hexadecanoyl-[acp] + Malonyl-[acyl-carrier protein] ↔ 3-Oxostearoyl-[acp] + Acyl-carrier protein + Carbon dioxide
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Acyl-[acyl-carrier protein]+Malonyl-[acyl-carrier protein]Thumb+Thumb+Acyl-carrier protein
Acyl-[acyl-carrier protein] + Malonyl-[acyl-carrier protein] ↔ 3-Oxoacyl-[acyl-carrier protein] + Carbon dioxide + Acyl-carrier protein
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SMPDB Reactions:
a malonyl-[acp]+a malonyl-[acp] methyl ester+ThumbThumb+a holo-[acyl-carrier protein]+3-Ketoglutaryl-[acp] methyl ester
a malonyl-[acp] + a malonyl-[acp] methyl ester + Hydrogen ionCarbon dioxide + a holo-[acyl-carrier protein] + 3-Ketoglutaryl-[acp] methyl ester
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cis-?3-decenoyl-ACP+Thumb+a malonyl-[acp]Thumb+a holo-[acyl-carrier protein]+3-oxo-cis-?5-dodecenoyl-[acp]?
cis-?3-decenoyl-ACP + Hydrogen ion + a malonyl-[acp] → Carbon dioxide + a holo-[acyl-carrier protein] + 3-oxo-cis-?5-dodecenoyl-[acp]?
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cis-?5-dodecenoyl-[acp]?+Thumb+a malonyl-[acp]a 3-oxo-cis-?7-tetradecenoyl-[acp]?+a holo-[acyl-carrier protein]+Thumb
cis-?5-dodecenoyl-[acp]? + Hydrogen ion + a malonyl-[acp] → a 3-oxo-cis-?7-tetradecenoyl-[acp]? + a holo-[acyl-carrier protein] + Carbon dioxide
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trans-?3-cis-?7-tetradecenoyl-[acp]+Thumb+ThumbThumb+cis-?7-tetradecenoyl-[acp]?
trans-?3-cis-?7-tetradecenoyl-[acp] + Hydrogen ion + NADHNAD + cis-?7-tetradecenoyl-[acp]?
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cis-?7-tetradecenoyl-[acp]?+Thumb+a malonyl-[acp]Thumb+a holo-[acyl-carrier protein]+3-oxo-cis-?9-hexadecenoyl-[acp]?
cis-?7-tetradecenoyl-[acp]? + Hydrogen ion + a malonyl-[acp] → Carbon dioxide + a holo-[acyl-carrier protein] + 3-oxo-cis-?9-hexadecenoyl-[acp]?
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2,3,4-saturated fatty acyl-[acp] +a malonyl-[acp]+ThumbThumb+a holo-[acyl-carrier protein]+3-oxoacyl-[acp]?
2,3,4-saturated fatty acyl-[acp] + a malonyl-[acp] + Hydrogen ionCarbon dioxide + a holo-[acyl-carrier protein] + 3-oxoacyl-[acp]?
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butyryl-[acp] +Thumb+a malonyl-[acp]a holo-[acyl-carrier protein]+Thumb+3-oxo-hexanoyl-[acp]?
butyryl-[acp] + Hydrogen ion + a malonyl-[acp] → a holo-[acyl-carrier protein] + Carbon dioxide + 3-oxo-hexanoyl-[acp]?
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hexanoyl-[acyl-carrier-protein] +Thumb+a malonyl-[acp]a holo-[acyl-carrier protein]+Thumb+3-oxo-octanoyl-[acp]?
hexanoyl-[acyl-carrier-protein] + Hydrogen ion + a malonyl-[acp] → a holo-[acyl-carrier protein] + Carbon dioxide + 3-oxo-octanoyl-[acp]?
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Octanoyl-[acyl-carrier protein] +Thumb+a malonyl-[acp]a holo-[acyl-carrier protein]+3-oxo-decanoyl-[acp]?+Thumb
Octanoyl-[acyl-carrier protein] + Hydrogen ion + a malonyl-[acp] → a holo-[acyl-carrier protein] + 3-oxo-decanoyl-[acp]? + Carbon dioxide
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decanoyl-[acp] +a malonyl-[acp]a holo-[acyl-carrier protein]+Thumb+3-oxo-dodecanoyl-[acp]?
decanoyl-[acp] + a malonyl-[acp] → a holo-[acyl-carrier protein] + Carbon dioxide + 3-oxo-dodecanoyl-[acp]?
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dodecanoyl-[acp]?+Thumb+a malonyl-[acp]a holo-[acyl-carrier protein]+Thumb+3-oxo-myristoyl-[acp]?
dodecanoyl-[acp]? + Hydrogen ion + a malonyl-[acp] → a holo-[acyl-carrier protein] + Carbon dioxide + 3-oxo-myristoyl-[acp]?
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trans tetradec-2-enoyl-[acp]+Thumb+ThumbThumb+ myristoyl-[acp]
trans tetradec-2-enoyl-[acp] + Hydrogen ion + NADHNAD + myristoyl-[acp]
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myristoyl-[acp]+Thumb+a malonyl-[acp]a holo-[acyl-carrier protein]+Thumb+3-oxo-palmitoyl-[acp]?
myristoyl-[acp] + Hydrogen ion + a malonyl-[acp] → a holo-[acyl-carrier protein] + Carbon dioxide + 3-oxo-palmitoyl-[acp]?
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a malonyl-[acp]+ThumbThumb+an acetyl-[acp]
a malonyl-[acp] + Hydrogen ionCarbon dioxide + an acetyl-[acp]
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a malonyl-[acp]+Thumb+an acetyl-[acp]Thumb+a holo-[acyl-carrier protein]+acetoacetyl-[acp]
a malonyl-[acp] + Hydrogen ion + an acetyl-[acp] → Carbon dioxide + a holo-[acyl-carrier protein] + acetoacetyl-[acp]
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PseudoCyc/BioCyc Reactions:
Butyryl-ACP (n-C4:0ACP)+Thumb+Malonyl-[acyl-carrier protein]3 -Oxohexanoyl-[acyl-carrier protein]+acyl carrier protein+Thumb
Butyryl-ACP (n-C4:0ACP) + Hydrogen ion + Malonyl-[acyl-carrier protein] → 3 -Oxohexanoyl-[acyl-carrier protein] + acyl carrier protein + Carbon dioxide
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Decanoyl-ACP (n-C10:0ACP)+Thumb+Malonyl-[acyl-carrier protein]3 -Oxododecanoyl-[acyl-carrier protein]+acyl carrier protein+Thumb
Decanoyl-ACP (n-C10:0ACP) + Hydrogen ion + Malonyl-[acyl-carrier protein] → 3 -Oxododecanoyl-[acyl-carrier protein] + acyl carrier protein + Carbon dioxide
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Thumb+Malonyl-[acyl-carrier protein]+Palmitoyl-ACP (n-C16:0ACP)3 -Oxooctadecanoyl-[acyl-carrier protein]+acyl carrier protein+Thumb
Hydrogen ion + Malonyl-[acyl-carrier protein] + Palmitoyl-ACP (n-C16:0ACP) → 3 -Oxooctadecanoyl-[acyl-carrier protein] + acyl carrier protein + Carbon dioxide
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Acetyl-ACP+Thumb+Malonyl-[acyl-carrier protein]acyl carrier protein+Acetoacetyl-ACP+Thumb
Acetyl-ACP + Hydrogen ion + Malonyl-[acyl-carrier protein] → acyl carrier protein + Acetoacetyl-ACP + Carbon dioxide
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Dodecanoyl-ACP (n-C12:0ACP)+Thumb+Malonyl-[acyl-carrier protein]3 -Oxotetradecanoyl-[acyl-carrier protein]+acyl carrier protein+Thumb
Dodecanoyl-ACP (n-C12:0ACP) + Hydrogen ion + Malonyl-[acyl-carrier protein] → 3 -Oxotetradecanoyl-[acyl-carrier protein] + acyl carrier protein + Carbon dioxide
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Thumb+Hexanoyl-ACP (n-C6:0ACP)+Malonyl-[acyl-carrier protein]3 -Oxooctanoyl-[acyl-carrier protein]+acyl carrier protein+Thumb
Hydrogen ion + Hexanoyl-ACP (n-C6:0ACP) + Malonyl-[acyl-carrier protein] → 3 -Oxooctanoyl-[acyl-carrier protein] + acyl carrier protein + Carbon dioxide
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Thumb+Malonyl-[acyl-carrier protein]+Myristoyl-ACP (n-C14:0ACP)3 -Oxohexadecanoyl-[acyl-carrier protein]+acyl carrier protein+Thumb
Hydrogen ion + Malonyl-[acyl-carrier protein] + Myristoyl-ACP (n-C14:0ACP) → 3 -Oxohexadecanoyl-[acyl-carrier protein] + acyl carrier protein + Carbon dioxide
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Thumb+Malonyl-[acyl-carrier protein]+Octanoyl-ACP (n-C8:0ACP)3 -Oxodecanoyl-[acyl-carrier protein]+acyl carrier protein+Thumb
Hydrogen ion + Malonyl-[acyl-carrier protein] + Octanoyl-ACP (n-C8:0ACP) → 3 -Oxodecanoyl-[acyl-carrier protein] + acyl carrier protein + Carbon dioxide
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cis-dec-3-enoyl-[acyl-carrier protein] (n-C10:1)+Thumb+Malonyl-[acyl-carrier protein]3 -oxo-cis-dodec-5-enoyl-[acyl-carrier protein]+acyl carrier protein+Thumb
cis-dec-3-enoyl-[acyl-carrier protein] (n-C10:1) + Hydrogen ion + Malonyl-[acyl-carrier protein] → 3 -oxo-cis-dodec-5-enoyl-[acyl-carrier protein] + acyl carrier protein + Carbon dioxide
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cis-dodec-5-enoyl-[acyl-carrier protein] (n-C12:1)+Thumb+Malonyl-[acyl-carrier protein]3 -oxo-cis-myristol-7-eoyl-[acyl-carrier protein]+acyl carrier protein+Thumb
cis-dodec-5-enoyl-[acyl-carrier protein] (n-C12:1) + Hydrogen ion + Malonyl-[acyl-carrier protein] → 3 -oxo-cis-myristol-7-eoyl-[acyl-carrier protein] + acyl carrier protein + Carbon dioxide
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Thumb+Malonyl-[acyl-carrier protein]+cis-tetradec-7-enoyl-[acyl-carrier protein] (n-C14:1)3 -oxo-cis-palm-9-eoyl-[acyl-carrier protein]+acyl carrier protein+Thumb
Hydrogen ion + Malonyl-[acyl-carrier protein] + cis-tetradec-7-enoyl-[acyl-carrier protein] (n-C14:1) → 3 -oxo-cis-palm-9-eoyl-[acyl-carrier protein] + acyl carrier protein + Carbon dioxide
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Thumb+Malonyl-[acyl-carrier protein]Acetyl-ACP+Thumb
Hydrogen ion + Malonyl-[acyl-carrier protein] → Acetyl-ACP + Carbon dioxide
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Glutaryl-[acyl-carrier protein] methyl ester+Thumb+Malonyl-[acyl-carrier protein]acyl carrier protein+Thumb+3 -Oxo-pimeloyl-[acyl-carrier protein] methyl ester
Glutaryl-[acyl-carrier protein] methyl ester + Hydrogen ion + Malonyl-[acyl-carrier protein] → acyl carrier protein + Carbon dioxide + 3 -Oxo-pimeloyl-[acyl-carrier protein] methyl ester
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Butyryl-[acp]+Malonyl-[acyl-carrier protein]3-Oxohexanoyl-[acp]+Thumb+Acyl-carrier protein
Butyryl-[acp] + Malonyl-[acyl-carrier protein] ↔ 3-Oxohexanoyl-[acp] + Carbon dioxide + Acyl-carrier protein
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Hexanoyl-[acp]+Malonyl-[acyl-carrier protein]3-Oxooctanoyl-[acp]+Thumb+Acyl-carrier protein
Hexanoyl-[acp] + Malonyl-[acyl-carrier protein] ↔ 3-Oxooctanoyl-[acp] + Carbon dioxide + Acyl-carrier protein
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Octanoyl-[acp]+Malonyl-[acyl-carrier protein]3-Oxodecanoyl-[acp]+Thumb+Acyl-carrier protein
Octanoyl-[acp] + Malonyl-[acyl-carrier protein] ↔ 3-Oxodecanoyl-[acp] + Carbon dioxide + Acyl-carrier protein
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Decanoyl-[acp]+Malonyl-[acyl-carrier protein]3-Oxododecanoyl-[acp]+Thumb+Acyl-carrier protein
Decanoyl-[acp] + Malonyl-[acyl-carrier protein] ↔ 3-Oxododecanoyl-[acp] + Carbon dioxide + Acyl-carrier protein
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Tetradecanoyl-[acp]+Malonyl-[acyl-carrier protein]3-Oxohexadecanoyl-[acp]+Thumb+Acyl-carrier protein
Tetradecanoyl-[acp] + Malonyl-[acyl-carrier protein] ↔ 3-Oxohexadecanoyl-[acp] + Carbon dioxide + Acyl-carrier protein
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Acetyl-[acyl-carrier protein]+Malonyl-[acyl-carrier protein]Acetoacetyl-[acp]+Thumb+Acyl-carrier protein
Acetyl-[acyl-carrier protein] + Malonyl-[acyl-carrier protein] ↔ Acetoacetyl-[acp] + Carbon dioxide + Acyl-carrier protein
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Dodecanoyl-[acyl-carrier protein]+Malonyl-[acyl-carrier protein]3-Oxotetradecanoyl-[acp]+Thumb+Acyl-carrier protein
Dodecanoyl-[acyl-carrier protein] + Malonyl-[acyl-carrier protein] ↔ 3-Oxotetradecanoyl-[acp] + Carbon dioxide + Acyl-carrier protein
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Hexadecanoyl-[acp]+Malonyl-[acyl-carrier protein]3-Oxostearoyl-[acp]+Acyl-carrier protein+Thumb
Hexadecanoyl-[acp] + Malonyl-[acyl-carrier protein] ↔ 3-Oxostearoyl-[acp] + Acyl-carrier protein + Carbon dioxide
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Acyl-[acyl-carrier-protein]+malonyl-[acyl-carrier-protein]3-oxoacyl-[acyl-carrier-protein]+Thumb+[acyl-carrier-protein]
Acyl-[acyl-carrier-protein] + malonyl-[acyl-carrier-protein] → 3-oxoacyl-[acyl-carrier-protein] + Carbon dioxide + [acyl-carrier-protein]
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Acyl-[acyl-carrier protein]+Malonyl-[acyl-carrier protein]Thumb+Thumb+Acyl-carrier protein
Acyl-[acyl-carrier protein] + Malonyl-[acyl-carrier protein] ↔ 3-Oxoacyl-[acyl-carrier protein] + Carbon dioxide + Acyl-carrier protein
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a malonyl-[acp]+a malonyl-[acp] methyl ester+ThumbThumb+a holo-[acyl-carrier protein]+3-Ketoglutaryl-[acp] methyl ester
a malonyl-[acp] + a malonyl-[acp] methyl ester + Hydrogen ionCarbon dioxide + a holo-[acyl-carrier protein] + 3-Ketoglutaryl-[acp] methyl ester
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cis-?3-decenoyl-ACP+Thumb+a malonyl-[acp]Thumb+a holo-[acyl-carrier protein]+3-oxo-cis-?5-dodecenoyl-[acp]?
cis-?3-decenoyl-ACP + Hydrogen ion + a malonyl-[acp] → Carbon dioxide + a holo-[acyl-carrier protein] + 3-oxo-cis-?5-dodecenoyl-[acp]?
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cis-?5-dodecenoyl-[acp]?+Thumb+a malonyl-[acp]a 3-oxo-cis-?7-tetradecenoyl-[acp]?+a holo-[acyl-carrier protein]+Thumb
cis-?5-dodecenoyl-[acp]? + Hydrogen ion + a malonyl-[acp] → a 3-oxo-cis-?7-tetradecenoyl-[acp]? + a holo-[acyl-carrier protein] + Carbon dioxide
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trans-?3-cis-?7-tetradecenoyl-[acp]+Thumb+ThumbThumb+cis-?7-tetradecenoyl-[acp]?
trans-?3-cis-?7-tetradecenoyl-[acp] + Hydrogen ion + NADHNAD + cis-?7-tetradecenoyl-[acp]?
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cis-?7-tetradecenoyl-[acp]?+Thumb+a malonyl-[acp]Thumb+a holo-[acyl-carrier protein]+3-oxo-cis-?9-hexadecenoyl-[acp]?
cis-?7-tetradecenoyl-[acp]? + Hydrogen ion + a malonyl-[acp] → Carbon dioxide + a holo-[acyl-carrier protein] + 3-oxo-cis-?9-hexadecenoyl-[acp]?
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2,3,4-saturated fatty acyl-[acp] +a malonyl-[acp]+ThumbThumb+a holo-[acyl-carrier protein]+3-oxoacyl-[acp]?
2,3,4-saturated fatty acyl-[acp] + a malonyl-[acp] + Hydrogen ionCarbon dioxide + a holo-[acyl-carrier protein] + 3-oxoacyl-[acp]?
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butyryl-[acp] +Thumb+a malonyl-[acp]a holo-[acyl-carrier protein]+Thumb+3-oxo-hexanoyl-[acp]?
butyryl-[acp] + Hydrogen ion + a malonyl-[acp] → a holo-[acyl-carrier protein] + Carbon dioxide + 3-oxo-hexanoyl-[acp]?
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hexanoyl-[acyl-carrier-protein] +Thumb+a malonyl-[acp]a holo-[acyl-carrier protein]+Thumb+3-oxo-octanoyl-[acp]?
hexanoyl-[acyl-carrier-protein] + Hydrogen ion + a malonyl-[acp] → a holo-[acyl-carrier protein] + Carbon dioxide + 3-oxo-octanoyl-[acp]?
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Octanoyl-[acyl-carrier protein] +Thumb+a malonyl-[acp]a holo-[acyl-carrier protein]+3-oxo-decanoyl-[acp]?+Thumb
Octanoyl-[acyl-carrier protein] + Hydrogen ion + a malonyl-[acp] → a holo-[acyl-carrier protein] + 3-oxo-decanoyl-[acp]? + Carbon dioxide
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decanoyl-[acp] +a malonyl-[acp]a holo-[acyl-carrier protein]+Thumb+3-oxo-dodecanoyl-[acp]?
decanoyl-[acp] + a malonyl-[acp] → a holo-[acyl-carrier protein] + Carbon dioxide + 3-oxo-dodecanoyl-[acp]?
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dodecanoyl-[acp]?+Thumb+a malonyl-[acp]a holo-[acyl-carrier protein]+Thumb+3-oxo-myristoyl-[acp]?
dodecanoyl-[acp]? + Hydrogen ion + a malonyl-[acp] → a holo-[acyl-carrier protein] + Carbon dioxide + 3-oxo-myristoyl-[acp]?
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trans tetradec-2-enoyl-[acp]+Thumb+ThumbThumb+ myristoyl-[acp]
trans tetradec-2-enoyl-[acp] + Hydrogen ion + NADHNAD + myristoyl-[acp]
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myristoyl-[acp]+Thumb+a malonyl-[acp]a holo-[acyl-carrier protein]+Thumb+3-oxo-palmitoyl-[acp]?
myristoyl-[acp] + Hydrogen ion + a malonyl-[acp] → a holo-[acyl-carrier protein] + Carbon dioxide + 3-oxo-palmitoyl-[acp]?
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a malonyl-[acp]+ThumbThumb+an acetyl-[acp]
a malonyl-[acp] + Hydrogen ionCarbon dioxide + an acetyl-[acp]
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a malonyl-[acp]+Thumb+an acetyl-[acp]Thumb+a holo-[acyl-carrier protein]+acetoacetyl-[acp]
a malonyl-[acp] + Hydrogen ion + an acetyl-[acp] → Carbon dioxide + a holo-[acyl-carrier protein] + acetoacetyl-[acp]
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Thumb
a 2,3,4-saturated fatty acyl-[acp] + a malonyl-[acp] + H+ → a holo-[acyl-carrier protein] + a 3-oxoacyl-[acp] + CO2
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PAMDB110387+PAMDB001633PAMDB000568+PAMDB110248
PAMDB110387+PAMDB001633PAMDB000568+PAMDB110248
PAMDB110387+PAMDB001633PAMDB000568+PAMDB110248
PAMDB110387+PAMDB001633PAMDB000568+PAMDB110248
PAMDB110387+PAMDB001633PAMDB000568+PAMDB110248
PAMDB001633PAMDB000568
PAMDB110387+PAMDB001633PAMDB110248+PAMDB000568
PAMDB110387+PAMDB001633PAMDB000568+PAMDB110248
PAMDB110387+PAMDB001633PAMDB000568+PAMDB110248
PAMDB120334+PAMDB001633PAMDB110248+PAMDB000568
PAMDB110387+PAMDB001633PAMDB000568+PAMDB110248
PAMDB110387+PAMDB001633PAMDB000568+PAMDB110248
PAMDB110387+PAMDB001633PAMDB000568+PAMDB110248
Complex Reactions:
Butyryl-ACP (n-C4:0ACP)+Thumb+Malonyl-[acyl-carrier protein]3 -Oxohexanoyl-[acyl-carrier protein]+acyl carrier protein+Thumb
Butyryl-ACP (n-C4:0ACP) + Hydrogen ion + Malonyl-[acyl-carrier protein] → 3 -Oxohexanoyl-[acyl-carrier protein] + acyl carrier protein + Carbon dioxide
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Decanoyl-ACP (n-C10:0ACP)+Thumb+Malonyl-[acyl-carrier protein]3 -Oxododecanoyl-[acyl-carrier protein]+acyl carrier protein+Thumb
Decanoyl-ACP (n-C10:0ACP) + Hydrogen ion + Malonyl-[acyl-carrier protein] → 3 -Oxododecanoyl-[acyl-carrier protein] + acyl carrier protein + Carbon dioxide
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Thumb+Malonyl-[acyl-carrier protein]+Palmitoyl-ACP (n-C16:0ACP)3 -Oxooctadecanoyl-[acyl-carrier protein]+acyl carrier protein+Thumb
Hydrogen ion + Malonyl-[acyl-carrier protein] + Palmitoyl-ACP (n-C16:0ACP) → 3 -Oxooctadecanoyl-[acyl-carrier protein] + acyl carrier protein + Carbon dioxide
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Acetyl-ACP+Thumb+Malonyl-[acyl-carrier protein]acyl carrier protein+Acetoacetyl-ACP+Thumb
Acetyl-ACP + Hydrogen ion + Malonyl-[acyl-carrier protein] → acyl carrier protein + Acetoacetyl-ACP + Carbon dioxide
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Dodecanoyl-ACP (n-C12:0ACP)+Thumb+Malonyl-[acyl-carrier protein]3 -Oxotetradecanoyl-[acyl-carrier protein]+acyl carrier protein+Thumb
Dodecanoyl-ACP (n-C12:0ACP) + Hydrogen ion + Malonyl-[acyl-carrier protein] → 3 -Oxotetradecanoyl-[acyl-carrier protein] + acyl carrier protein + Carbon dioxide
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Thumb+Hexanoyl-ACP (n-C6:0ACP)+Malonyl-[acyl-carrier protein]3 -Oxooctanoyl-[acyl-carrier protein]+acyl carrier protein+Thumb
Hydrogen ion + Hexanoyl-ACP (n-C6:0ACP) + Malonyl-[acyl-carrier protein] → 3 -Oxooctanoyl-[acyl-carrier protein] + acyl carrier protein + Carbon dioxide
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Thumb+Malonyl-[acyl-carrier protein]+Myristoyl-ACP (n-C14:0ACP)3 -Oxohexadecanoyl-[acyl-carrier protein]+acyl carrier protein+Thumb
Hydrogen ion + Malonyl-[acyl-carrier protein] + Myristoyl-ACP (n-C14:0ACP) → 3 -Oxohexadecanoyl-[acyl-carrier protein] + acyl carrier protein + Carbon dioxide
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Thumb+Malonyl-[acyl-carrier protein]+Octanoyl-ACP (n-C8:0ACP)3 -Oxodecanoyl-[acyl-carrier protein]+acyl carrier protein+Thumb
Hydrogen ion + Malonyl-[acyl-carrier protein] + Octanoyl-ACP (n-C8:0ACP) → 3 -Oxodecanoyl-[acyl-carrier protein] + acyl carrier protein + Carbon dioxide
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cis-dec-3-enoyl-[acyl-carrier protein] (n-C10:1)+Thumb+Malonyl-[acyl-carrier protein]3 -oxo-cis-dodec-5-enoyl-[acyl-carrier protein]+acyl carrier protein+Thumb
cis-dec-3-enoyl-[acyl-carrier protein] (n-C10:1) + Hydrogen ion + Malonyl-[acyl-carrier protein] → 3 -oxo-cis-dodec-5-enoyl-[acyl-carrier protein] + acyl carrier protein + Carbon dioxide
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cis-dodec-5-enoyl-[acyl-carrier protein] (n-C12:1)+Thumb+Malonyl-[acyl-carrier protein]3 -oxo-cis-myristol-7-eoyl-[acyl-carrier protein]+acyl carrier protein+Thumb
cis-dodec-5-enoyl-[acyl-carrier protein] (n-C12:1) + Hydrogen ion + Malonyl-[acyl-carrier protein] → 3 -oxo-cis-myristol-7-eoyl-[acyl-carrier protein] + acyl carrier protein + Carbon dioxide
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Thumb+Malonyl-[acyl-carrier protein]+cis-tetradec-7-enoyl-[acyl-carrier protein] (n-C14:1)3 -oxo-cis-palm-9-eoyl-[acyl-carrier protein]+acyl carrier protein+Thumb
Hydrogen ion + Malonyl-[acyl-carrier protein] + cis-tetradec-7-enoyl-[acyl-carrier protein] (n-C14:1) → 3 -oxo-cis-palm-9-eoyl-[acyl-carrier protein] + acyl carrier protein + Carbon dioxide
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Thumb+Malonyl-[acyl-carrier protein]Acetyl-ACP+Thumb
Hydrogen ion + Malonyl-[acyl-carrier protein] → Acetyl-ACP + Carbon dioxide
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Glutaryl-[acyl-carrier protein] methyl ester+Thumb+Malonyl-[acyl-carrier protein]acyl carrier protein+Thumb+3 -Oxo-pimeloyl-[acyl-carrier protein] methyl ester
Glutaryl-[acyl-carrier protein] methyl ester + Hydrogen ion + Malonyl-[acyl-carrier protein] → acyl carrier protein + Carbon dioxide + 3 -Oxo-pimeloyl-[acyl-carrier protein] methyl ester
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Acyl-[acyl-carrier-protein]+malonyl-[acyl-carrier-protein]3-oxoacyl-[acyl-carrier-protein]+Thumb+[acyl-carrier-protein]
Acyl-[acyl-carrier-protein] + malonyl-[acyl-carrier-protein] → 3-oxoacyl-[acyl-carrier-protein] + Carbon dioxide + [acyl-carrier-protein]
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000568Carbon dioxideMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB003556malonyl-CoA methyl esterMetaboCard
PAMDB000197NADMetaboCard
PAMDB000398NADHMetaboCard
GO Classification:
Function
catalytic activity
Process
biosynthetic process
metabolic process
Gene Properties
Locus tag: PA1609
Strand: -
Entrez Gene ID: 881925
Accession: NP_250300.1
GI: 15596806
Sequence start: 1751674
Sequence End: 1752891
Sequence Length: 1217
Gene Sequence:
>PA1609
ATGCGTCGCGTCGTTATCACCGGTCTGGGCATCGTTTCCTGCCTCGGCAATGACAAAGACACCGTTTCCGCCAACCTCCGTGCGGGTCGGCCCGGCATTCGCTTCAATCCGTCCTACGCCGAGATGGGCCTGCGCAGCCACGTTTCCGGTTCGGTCGACCTGAACCTCGAAGAGCTGATCGATCGCAAGGTCTTCCGCTTCATGGGCGATGCCGCCGCCTACGCCTACCTGGCGATGGAGCAGGCGATCAAGGACTCCGGCCTGACTCCGGAACAGATTTCCAACCCCCGCACCGGCCTGATCGCCGGCTCCGGCGGCGCTTCCACCCTGAACCAGATGGAAGCCATCGATACCCTGCGCGAGAAAGGCGTCAAGCGCATCGGCCCATACCGCGTGACCCGCACCATGGGCAGCACCGTATCGGCCTGCCTGGCCACGCCGTTCCAGATCAAGGGCGTCAACTACTCGATCTCCTCCGCCTGCGCCACCAGCGCGCATTGCATCGGCCAGGCCATGGAACAAATCCAGCTGGGCAAGCAGGACGTGGTCTTCGCCGGCGGCGGCGAAGAGGAACACTGGAGCCAGAGCTGCCTGTTCGACGCCATGGGCGCCCTCTCCACCCAGTACAACGAGACGCCGGAAAAGGCCTCCCGCGCCTACGACGCCAAGCGTGACGGCTTCGTCATCGCCGGCGGCGGCGGCATGGTGGTGGTCGAGGGGCTGGAGCATGCGCTCAAGCGCGGCGCCAAGATCTACGCCGAGATCGTCGGCTACGGCGCCACCTCCGACGGCTACGACATGGTCGCCCCGAGCGGCGAAGGCGCGATCCGCTGCATGCAGCAGGCGCTGGCCACCGTCGACGCGCCGATCGACTACCTGAACACCCACGGCACCTCCACCCCGGTCGGCGACGTCGCCGAGATCCGAGGCGTGCGCGAAGTGTTCGGCGACAAGGCGCCGGCCATCAGCTCGACGAAGAGCCTGTCCGGCCACTCGCTGGGCGCCGCCGGCGTACACGAGGCGATCTATTGCCTGCTGATGATGGAAGGCGGCTTCATCGCCGGCTCCGCCAACATCGACGAACTCGACCCGGAAGTGGCCGACCTGCCGATTCTCCGCGAGACCCGCGAGAACGCCAAGCTCGATACCGTCATGAGCAACAGCTTCGGCTTCGGCGGCACCAACGCCACCCTGGTCCTCAAGCGCTGGCAGGGTTGA
Protein Properties
Protein Residues: 405
Protein Molecular Weight: 42.8 kDa
Protein Theoretical pI: 5.28
Hydropathicity (GRAVY score): -0.087
Charge at pH 7 (predicted): -7.52
Protein Sequence:
>PA1609
MRRVVITGLGIVSCLGNDKDTVSANLRAGRPGIRFNPSYAEMGLRSHVSGSVDLNLEELIDRKVFRFMGDAAAYAYLAMEQAIKDSGLTPEQISNPRTGLIAGSGGASTLNQMEAIDTLREKGVKRIGPYRVTRTMGSTVSACLATPFQIKGVNYSISSACATSAHCIGQAMEQIQLGKQDVVFAGGGEEEHWSQSCLFDAMGALSTQYNETPEKASRAYDAKRDGFVIAGGGGMVVVEGLEHALKRGAKIYAEIVGYGATSDGYDMVAPSGEGAIRCMQQALATVDAPIDYLNTHGTSTPVGDVAEIRGVREVFGDKAPAISSTKSLSGHSLGAAGVHEAIYCLLMMEGGFIAGSANIDELDPEVADLPILRETRENAKLDTVMSNSFGFGGTNATLVLKRWQG
References
External Links:
Resource Link
Genome ID: PA1609
Entrez Gene ID: 881925
NCBI Protein ID: 15596806
General Reference: PaperBLAST - Find papers about PA1609 and its homologs