Citrate synthase (PA1580)

Identification
Name: Citrate synthase
Synonyms: Not Available
Gene Name: gltA
Enzyme Class:
Biological Properties
General Function: Involved in transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer
Specific Function: Acetyl-CoA + H(2)O + oxaloacetate = citrate + CoA
Cellular Location: Not Available
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb+Thumb ↔ Thumb+Thumb+Thumb
Acetyl-CoA + Water + Oxalacetic acid ↔ Citric acid + Coenzyme A + Hydrogen ion
ReactionCard
Thumb+Thumb ↔ Thumb+Thumb+Thumb
Citric acid + Coenzyme A ↔ Acetyl-CoA + Water + Oxalacetic acid
ReactionCard
SMPDB Reactions:
Thumb+Thumb+Thumb → Thumb+Thumb+Thumb
Oxalacetic acid + Water + Acetyl-CoA → Citric acid + Coenzyme A + Hydrogen ion
ReactionCard
PseudoCyc/BioCyc Reactions:
Thumb+Thumb+Thumb ↔ Thumb+Thumb+Thumb
Acetyl-CoA + Water + Oxalacetic acid ↔ Citric acid + Coenzyme A + Hydrogen ion
ReactionCard
Complex Reactions: Not Available
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000298Acetyl-CoAMetaboCard
PAMDB000034Citric acidMetaboCard
PAMDB000381Coenzyme AMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB000092Oxalacetic acidMetaboCard
PAMDB000142WaterMetaboCard
GO Classification:
Component
cell part
cytoplasm
intracellular part
Function
catalytic activity
citrate (Si)-synthase activity
transferase activity
transferase activity, transferring acyl groups
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer
Process
acetyl-CoA catabolic process
acetyl-CoA metabolic process
carbohydrate metabolic process
cellular carbohydrate metabolic process
cellular metabolic process
coenzyme metabolic process
cofactor metabolic process
metabolic process
primary metabolic process
tricarboxylic acid cycle
Gene Properties
Locus tag: PA1580
Strand: -
Entrez Gene ID: 882117
Accession: NP_250271.1
GI: 15596777
Sequence start: 1719109
Sequence End: 1720395
Sequence Length: 1286
Gene Sequence: 
>PA1580
ATGGCTGACAAAAAAGCGCAGTTGATCATCGAGGGCTCAGCCCCCGTCGAACTGCCCGTCCTATCCGGTACCATGGGTCCCGATGTAGTGGATGTACGGGGCCTCACCGCCACGGGCCACTTCACCTTCGATCCTGGCTTCATGTCGACCGCCTCCTGCGAGTCGAAGATCACCTATATCGACGGCGACAAAGGCGTCCTCCTCCATCGCGGCTACCCCATCGAGCAACTGGCAGAGAAATCCGACTACCTGGAAACCTGCTACCTGCTGCTGAACGGCGAGCTGCCCACCGCCGCGCAGAAGGAACAGTTCGTCGGCACCATCAAGAACCACACCATGGTTCACGAGCAGTTGAAGACCTTCTTCAACGGCTTCCGCCGCGACGCCCACCCGATGGCCGTGATGTGCGGCGTGATCGGCGCCCTCTCGGCCTTCTACCACGACTCCCTGGACATCAATAACCCGAAGCATCGCGAAGTCTCCGCGCATCGCCTGATCGCCAAGATGCCGACCATCGCCGCCATGGTGTACAAGTACTCCAAGGGCGAGCCGATGATGTATCCGCGTAACGACCTGAACTACGCGGAAAACTTCCTGCACATGATGTTCAACACCCCCTGCGAGACCAAGCCGATCAGCCCCGTGCTGGCCAAGGCCATGGACCGCATCTTCATTCTCCACGCCGACCACGAGCAGAACGCCTCCACCTCCACGGTGCGTCTGGCCGGCTCCTCCGGCGCCAATCCGTTCGCCTGCATCGCCTCCGGCATCGCCGCCCTGTGGGGACCGGCCCATGGCGGCGCGAACGAAGCGGTGCTGCGCATGCTCGACGAGATCGGCGACGTGTCCAACATCGACAAGTTCGTCGAGAAGGCCAAGGACAAGAACGATCCGTTCAAGCTGATGGGCTTCGGCCATCGTGTCTACAAGAACTTCGACCCGCGCGCCAAGGTCATGAAGCAGACCTGCGACGAGGTCCTCCAGGAGCTGGGCATCAACGACCCGCAACTGGAACTGGCGATGAAGCTAGAAGAAATCGCCCGCCACGACCCCTACTTCGTGGAACGCAACCTGTACCCGAACGTCGACTTCTACTCGGGGATCATCCTCAAGGCGATCGGCATTCCGACCAGCATGTTCACCGTGATCTTCGCCCTGGCGCGTACCGTCGGCTGGATCTCGCACTGGCAGGAAATGCTCTCCGGCCCCTACAAGATCGGCCGCCCGCGCCAGCTCTATACCGGCCACACCCAGCGCGACTTCACCGCCCTCAAGGATCGCGGCTGA
Protein Properties
Protein Residues: 428
Protein Molecular Weight: 47.7 kDa
Protein Theoretical pI: 6.96
Hydropathicity (GRAVY score): -0.206
Charge at pH 7 (predicted): -0.33
Protein Sequence: 
>PA1580
MADKKAQLIIEGSAPVELPVLSGTMGPDVVDVRGLTATGHFTFDPGFMSTASCESKITYIDGDKGVLLHRGYPIEQLAEKSDYLETCYLLLNGELPTAAQKEQFVGTIKNHTMVHEQLKTFFNGFRRDAHPMAVMCGVIGALSAFYHDSLDINNPKHREVSAHRLIAKMPTIAAMVYKYSKGEPMMYPRNDLNYAENFLHMMFNTPCETKPISPVLAKAMDRIFILHADHEQNASTSTVRLAGSSGANPFACIASGIAALWGPAHGGANEAVLRMLDEIGDVSNIDKFVEKAKDKNDPFKLMGFGHRVYKNFDPRAKVMKQTCDEVLQELGINDPQLELAMKLEEIARHDPYFVERNLYPNVDFYSGIILKAIGIPTSMFTVIFALARTVGWISHWQEMLSGPYKIGRPRQLYTGHTQRDFTALKDRG
References
External Links:
Resource Link
Genome ID: PA1580
Entrez Gene ID: 882117
NCBI Protein ID: 15596777
General Reference: PaperBLAST - Find papers about PA1580 and its homologs