Identification |
Name: |
NADP-dependent malic enzyme |
Synonyms: |
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Gene Name: |
maeB |
Enzyme Class: |
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Biological Properties |
General Function: |
Involved in oxidoreductase activity |
Specific Function: |
(S)-malate + NADP(+) = pyruvate + CO(2) + NADPH |
Cellular Location: |
Not Available |
KEGG Pathways: |
- Carbon fixation in photosynthetic organisms pae00710
- Metabolic pathways pae01100
- Microbial metabolism in diverse environments pae01120
- Pyruvate metabolism pae00620
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KEGG Reactions: |
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SMPDB Reactions: |
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L-Malic acid | + | | + | | → | | + | NADPH | + | | + | |
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PseudoCyc/BioCyc Reactions: |
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Complex Reactions: |
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Transports: |
Not Available |
Metabolites: |
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GO Classification: |
Function |
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acyltransferase activity | binding | catalytic activity | cation binding | ion binding | metal ion binding | NAD or NADH binding | nucleotide binding | oxidoreductase activity | oxidoreductase activity, acting on CH-OH group of donors | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | transferase activity | transferase activity, transferring acyl groups | transferase activity, transferring acyl groups other than amino-acyl groups | Process |
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metabolic process | oxidation reduction |
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Gene Properties |
Locus tag: |
PA5046 |
Strand: |
- |
Entrez Gene ID: |
881142 |
Accession: |
NP_253733.1 |
GI: |
15600239 |
Sequence start: |
5683471 |
Sequence End: |
5684739 |
Sequence Length: |
1268 |
Gene Sequence: |
>PA5046
ATGTCCGATCTTAAAACCGCTGCCCTCGAATATCACGCACAACCCCGTCCGGGAAAACTGAGTGTCGAGCTGACCAAACCCACCGCTACCGCCCGGGACCTGTCCCTGGCCTACAGCCCGGGTGTCGCCGAGCCGGTGCGTGAAATCGCCCGCGATGCCGAGCTGGCCTACCAGTACACCGGCAAGGGCAACCTGGTGGCAGTGATTTCCGACGGCACCGCGATTCTCGGCCTGGGTAACCTCGGCCCGCTGGCCTCCAAGCCGGTGATGGAAGGCAAGGGTGTGCTGTTCAAGCGCTTCGCCGGCATCGACGTGTTCGACATCGAGGTCGACGCCGAGAGCCCGCAGGCTTTCATCGATACCGTCAAGCGTATTTCCATCACCTTCGGCGGTATCAACCTCGAGGACATCAAGGCTCCCGAGTGTTTCGAGATCGAGCGCGCGCTGATCGAACAGTGCGACATCCCGGTGTTCCACGATGACCAGCACGGCACCGCCATCGTGACCGCGGCGGGCATGCTCAACGCGCTGGAACTGGCCGGCAAGAAGCTGGAAGAAGCGAAGATCGTCTGCCTCGGCGCCGGCGCTGCCGCCATCTCCTGCATGAAGCTGCTGGTGAGCATGGGCGCCAAGGTCGAGAACATCTACATGATCGACCGCAAGGGCGTGATCCACGCCGGTCGCGACGATCTGAACCAGTACAAGTCGGTGTTCGCCACCGAGACCGACAAGCGCACCCTGGCCGACGCCCTGGAGGGCGCCGACGTGTTCGTCGGCCTGTCCGGCGCCAACCTGCTGGAGCCGGAAGACCTCAAGCGCATGGCGCCGAACCCGATCGTGTTCGCCTGCTCGAACCCGGACCCGGAGATCAAGCCGGAACTGGCCCATGCCACCCGTAACGACGTGATCATGGCTACCGGTCGTTCCGACTATCCGAATCAGGTCAACAACGTGCTCGGTTTCCCCTTCATCTTCCGTGGTGCCCTGGACGTACGTGCCACGCGCATCAACGAAGAGATGAAGATCGCCGCCGCCCTGGCCCTGCGCGACCTGGCCAAGCAGCCGGTCCCGGAAGACGTCTGCGCCGCCTATGGCGTGGACAAGCTGGAATTCGGCCGCGAGTACATCATTCCGAAGCCGATGGACAAGCGCCTGATCACCGTGGTCTCCGATGCCGTGGCCAAGGCTGCCATCGAGACCGGCGTGGCTACCCTGCCGTATCCGAAGAACTATCCGCTGAAATCGGTGGACGACGTCTTCAACGGCTGA |
Protein Properties |
Protein Residues: |
422 |
Protein Molecular Weight: |
45.4 kDa |
Protein Theoretical pI: |
4.81 |
Hydropathicity (GRAVY score): |
0.001 |
Charge at pH 7 (predicted): |
-11.96 |
Protein Sequence: |
>PA5046
MSDLKTAALEYHAQPRPGKLSVELTKPTATARDLSLAYSPGVAEPVREIARDAELAYQYTGKGNLVAVISDGTAILGLGNLGPLASKPVMEGKGVLFKRFAGIDVFDIEVDAESPQAFIDTVKRISITFGGINLEDIKAPECFEIERALIEQCDIPVFHDDQHGTAIVTAAGMLNALELAGKKLEEAKIVCLGAGAAAISCMKLLVSMGAKVENIYMIDRKGVIHAGRDDLNQYKSVFATETDKRTLADALEGADVFVGLSGANLLEPEDLKRMAPNPIVFACSNPDPEIKPELAHATRNDVIMATGRSDYPNQVNNVLGFPFIFRGALDVRATRINEEMKIAAALALRDLAKQPVPEDVCAAYGVDKLEFGREYIIPKPMDKRLITVVSDAVAKAAIETGVATLPYPKNYPLKSVDDVFNG |
References |
External Links: |
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General Reference: |
PaperBLAST - Find papers about PA5046 and its homologs
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