Biosynthetic arginine decarboxylase (PA4839)

Identification
Name: Biosynthetic arginine decarboxylase
Synonyms:
  • ADC
Gene Name: speA
Enzyme Class:
Biological Properties
General Function: Involved in catalytic activity
Specific Function: Catalyzes the biosynthesis of agmatine from arginine
Cellular Location: Periplasm
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb ↔ Thumb+Thumb
L-Arginine + Hydrogen ion ↔ Agmatine + Carbon dioxide
ReactionCard
Thumb ↔ Thumb+Thumb
L-Arginine ↔ Agmatine + Carbon dioxide
ReactionCard
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
Thumb+Thumb ↔ Thumb+Thumb
L-Arginine + Hydrogen ion ↔ Agmatine + Carbon dioxide
ReactionCard
Complex Reactions:
Thumb → Thumb+Thumb
L-Arginine → Agmatine + Carbon dioxide
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000385AgmatineMetaboCard
PAMDB000568Carbon dioxideMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB000146L-ArginineMetaboCard
GO Classification:
Function
arginine decarboxylase activity
carbon-carbon lyase activity
carboxy-lyase activity
catalytic activity
lyase activity
Process
arginine catabolic process
arginine metabolic process
cellular amino acid and derivative metabolic process
cellular amino acid derivative metabolic process
cellular amino acid metabolic process
cellular biogenic amine metabolic process
cellular metabolic process
glutamine family amino acid metabolic process
metabolic process
polyamine biosynthetic process
polyamine metabolic process
spermidine biosynthetic process
Gene Properties
Locus tag: PA4839
Strand: -
Entrez Gene ID: 879594
Accession: NP_253526.1
GI: 15600032
Sequence start: 5431381
Sequence End: 5433291
Sequence Length: 1910
Gene Sequence: 
>PA4839
ATGGCCGCTCGACGGACTCGCAAAGACGATGGCAGCAACTGGACCGTGGCCGACAGCCGCGGCGTATACGGCATCCGCCACTGGGGTGCGGGTTATTTCGCCATCAACGATGGCGGCAATGTCGAAGTGCGTCCGCAGGGTGCCGACTCGACGCCCATCGATCTCTACGAGCTGGTCGGCCAGCTGCGCGAGGCGGGCCTGAGCCTGCCGCTGCTGGTGCGCTTCCCGGATATCCTGCAGGACCGCGTGCGCAAGCTCACCGGCGCCTTCGACGCGAACATCGAGCGCCTCGAATACCAGAGCCGCTATACCGCGCTGTATCCGATCAAGGTCAACCAGCAGGAAGCGGTGGTGGAGAACATCATCGCCACCGAGAACGTCTCCATCGGCCTGGAGGCAGGCTCCAAGCCGGAACTCATGGCGGTGCTGGCGCTGGCCCCGAAGGGCGGCACCATCGTCTGCAACGGCTACAAGGACCGCGAGTTCATCAAGCTGGCGCTGATGGGGCAGAAGCTCGGGCACAACGTGTTCATCGTGATCGAGAAGGAATCCGAGGTGCAGCTGGTGATCGAGGAGGCCGCCAACGTCGGCGTGCAGCCCCAGGTCGGCCTGCGCGTGCGGCTGTCCTCGCTGGCTTCGTCGAAGTGGGCAGACACCGGTGGCGAGAAGGCCAAGTTCGGCCTTTCCGCCGCCCAGCTGCTGTCGGTGGTCGAGCGCTTCCGCCAGGCCGGTCTCGACCAGGGCGTGCGCCTGCTGCATTTCCACATGGGCTCGCAGATCGCCAACCTGGCCGACTACCAGCACGGCTTCAAGGAAGCCATCCGCTACTACGGCGAGCTGCGCGCGCTCGGCCTGCCGGTGGATCACATCGACGTTGGCGGCGGCCTCGGCGTCGACTACGACGGCACCCATTCGCGCAACGCCAGCTCGATCAACTACGACATCGATGACTATGCCGGCGTGGTGGTCGGCATGCTCAAGGAGTTCTGCGACGCCCAGGGCCTGCCGCATCCGCACATCTTCTCGGAGAGCGGCCGGGCGCTGACCGCGCACCATGCGGTGCTGATCACCCAGGTCACCGACGTCGAGCGGCACAACGACGACGTGCCGAAGATCGTCGATCTCGACGAGCAGCCGGAGATCGTCCGCTGGCTGGCCGAACTGCTCGGCCCGACCGATGCCGAGATGGTCACCGAGACCTACTGGCGCGCCACCCACTACATCGGCGACGCCGCCGCGCAGTATGCCGACGGCAAGATCAGCCTGGCGCAGAAAGCCCTCGCCGAGCAGTGCTACTTCGCTATCTGCCGGCGCCTGCACAACCAGCTCAAGGCCCGCCAGCGCTCCCACCGGCAGGTCCTCGACGAACTCAACGACAAGCTCGCCGACAAGTACATCTGCAACTTCTCGGTGTTCCAGAGCCTGCCGGATACCTGGGCCATCGGCCAGGTGCTGCCGATCCTGCCGCTGCACCGCCTGGGCGAGGAGCCGGATCGGCGCGCGGTACTGCAGGACCTGACCTGCGACTCCGACGGCAAGATCACCCAGTACGTCGACGAGCAGAGCATCGAGACCAGCCTGCCGGTGCACGAGGTGAAGGAGGGCGAGGACTACCTGATCGGGGTATTCCTGGTCGGCGCCTACCAGGAGATCCTCGGCGACATGCACAACCTGTTCGGCGACACCGACTCGGTGAACGTCTACCAGCGCGCAGACGGCGGCATCTATCACGCCGGCATCGAGACCCACGACACCATCGAGGACATGCTGCGCTACGTGCACCTGTCGCCGGAGGAACTGATGACCCTCTACCGCGACAAGGTCGCCGGGGCCAAGCTCACCGCCCGCGAGCGCAACCAGTACCTGGATGCGCTGCGCCTGGGGCTGACCCGCTCGGCGTACCTGTCCTGA
Protein Properties
Protein Residues: 636
Protein Molecular Weight: 70.7 kDa
Protein Theoretical pI: 5.16
Hydropathicity (GRAVY score): -0.245
Charge at pH 7 (predicted): -21.1
Protein Sequence: 
>PA4839
MAARRTRKDDGSNWTVADSRGVYGIRHWGAGYFAINDGGNVEVRPQGADSTPIDLYELVGQLREAGLSLPLLVRFPDILQDRVRKLTGAFDANIERLEYQSRYTALYPIKVNQQEAVVENIIATENVSIGLEAGSKPELMAVLALAPKGGTIVCNGYKDREFIKLALMGQKLGHNVFIVIEKESEVQLVIEEAANVGVQPQVGLRVRLSSLASSKWADTGGEKAKFGLSAAQLLSVVERFRQAGLDQGVRLLHFHMGSQIANLADYQHGFKEAIRYYGELRALGLPVDHIDVGGGLGVDYDGTHSRNASSINYDIDDYAGVVVGMLKEFCDAQGLPHPHIFSESGRALTAHHAVLITQVTDVERHNDDVPKIVDLDEQPEIVRWLAELLGPTDAEMVTETYWRATHYIGDAAAQYADGKISLAQKALAEQCYFAICRRLHNQLKARQRSHRQVLDELNDKLADKYICNFSVFQSLPDTWAIGQVLPILPLHRLGEEPDRRAVLQDLTCDSDGKITQYVDEQSIETSLPVHEVKEGEDYLIGVFLVGAYQEILGDMHNLFGDTDSVNVYQRADGGIYHAGIETHDTIEDMLRYVHLSPEELMTLYRDKVAGAKLTARERNQYLDALRLGLTRSAYLS
References
External Links:
Resource Link
Genome ID: PA4839
Entrez Gene ID: 879594
NCBI Protein ID: 15600032
General Reference: PaperBLAST - Find papers about PA4839 and its homologs