Identification
Name: NADH dehydrogenase
Synonyms: Not Available
Gene Name: ndh
Enzyme Class:
Biological Properties
General Function: Involved in oxidation-reduction process
Specific Function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation
Cellular Location: Cell membrane
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb+AcceptorThumb+Reduced acceptor
NADH + Hydrogen ion + Acceptor ↔ NAD + Reduced acceptor
ReactionCard
SMPDB Reactions:
Thumb+ThumbThumb+Thumb
PseudoCyc/BioCyc Reactions:
Thumb+a ubiquinone+Thumba ubiquinol+Thumb
Hydrogen ion + a ubiquinone + NADH ↔ a ubiquinol + NAD
ReactionCard
Thumb+Thumb ? Thumb+Thumb+Cu+
Thumb+a ubiquinone+Thumba ubiquinol+Thumb
Hydrogen ion + a ubiquinone + NADH → a ubiquinol + NAD
ReactionCard
Complex Reactions:
Thumb+4 Thumb+ThumbThumb+Thumb+3 Thumb
4 Thumb+Thumb+ThumbThumb+Thumb+3 Thumb
4 Thumb+Menaquinone 8+ThumbThumb+Thumb+3 Thumb
Thumb+Thumb+ThumbThumb+Thumb
Thumb+Thumb+ThumbThumb+Thumb
Thumb+Menaquinone 8+ThumbThumb+Thumb
Thumb+acceptorThumb+reduced acceptor
NADH + acceptor → NAD + reduced acceptor
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB0015632-Demethylmenaquinol 8MetaboCard
PAMDB0015642-Demethylmenaquinone 8MetaboCard
PAMDB000166CopperMetaboCard
PAMDB003393Cu(+)MetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB001653Menaquinol 8MetaboCard
PAMDB000197NADMetaboCard
PAMDB000398NADHMetaboCard
PAMDB000237Ubiquinol-8MetaboCard
PAMDB001700Ubiquinone-8MetaboCard
GO Classification:
Function
adenyl nucleotide binding
binding
catalytic activity
FAD or FADH2 binding
nucleoside binding
oxidoreductase activity
purine nucleoside binding
Process
metabolic process
oxidation reduction
Gene Properties
Locus tag: PA4538
Strand: +
Entrez Gene ID: 878460
Accession: NP_253228.1
GI: 15599734
Sequence start: 5077770
Sequence End: 5079077
Sequence Length: 1307
Gene Sequence:
>PA4538
ATGTCCCATCGCATCGTGATCGTCGGCGGCGGCGCCGGCGGGCTGGAGCTCGCCACCCGTCTCGGCCGCACCCTGGGTAAACGCGGCAAGGCCCAGGTCACCCTGGTCGACGCCAACCTCACCCACATCTGGAAACCCCTGCTGCACGAAGTCGCTGCCGGCTCGCTCAACTCCTCCGAGGACGAGCTGAACTACGTCGCCCAGGCGAAGTGGAACCACTTCGAATTCCAGCTCGGCCGCATGCAGGGCCTGGATCGCGCCGGCAAGCGGGTCCGCCTGGCCGCACTGGTGGACGAGAATGGCGTTGAACTGGTTCCCGAGCGCGACATCGCCTACGACACCCTGGTGATCGCTGTCGGCAGCACCACCAACGACTTCGGCACCGAGGGCGCTGCGGAACATTGCATTTTCCTCGATACCCGCGCCCAGGCCGAACGCTTCCACCGACAACTACTCGGCCAGTACCTGCGTGCGCATACCGGGCACGACGCGAACAACAACGCAGTGAGTATCGCCATCATCGGCGCCGGCGCCACCGGCGTCGAACTGGCTGCGGAACTGCACCACGCCGCGCAGATGCTGGCCGCCTACGGGCTCGACCGGATCCGCCCGGAAGACCTGCACATCAGCCTGGTCGAAGCCGGCCCGCGGGTGCTGCCGGCGCTGCCCGAGCGTATCAGCCAGCCGGTACACCAGACCCTGAGCAAGCTCGGCGTACGGGTGATGACCGGCTCCGCGGTGAGCAAGGTAGATGCGGACGGCCTCTGGACCGGCGACGGCGAATTCGTCCCGGCGACGCTCAAGGTGTGGGCGGCGGGCATCCGGGCTCCGGCCTTCCTCAAGGAACTCGACGGCCTGGAAAGCAACCGTATCAACCAACTGGTGGTCCGCCCGACCCTGCAGACCACCCGCGACGACGACATCTTCGCCTTCGGCGACTGCGCCGCCTGTCCCCAGCCGGCGCAACCGGGAGAGCAACCGCGCAACGTGCCGCCACGCGCCCAGGCCGCGCACCAGCAGGCCTCGCTGCTGGTGAAATCGCTACGTGCCCGTCTCGAAGGCAAGCCGCTGGGCGAATATCACTACCGCGACTACGGTTCGCTGATCTCGCTGTCGCGCTTCAGCGCGGTCGGCAACCTGATGGGCAATCTGATGGGTAGCGTCATGCTCGAAGGCTGGCTGGCGCGGATGTTCTACGTATCGCTATACCGCATGCACCAGATGGCGTTGTACGGTCCGCTGCGCACCGCGATGCTGATGCTTAGCGGCCGCCTGCGCAGCACCGAGCCACGCCTCAAGCTGCACTGA
Protein Properties
Protein Residues: 435
Protein Molecular Weight: 47.4 kDa
Protein Theoretical pI: 8.47
Hydropathicity (GRAVY score): -0.121
Charge at pH 7 (predicted): 5.76
Protein Sequence:
>PA4538
MSHRIVIVGGGAGGLELATRLGRTLGKRGKAQVTLVDANLTHIWKPLLHEVAAGSLNSSEDELNYVAQAKWNHFEFQLGRMQGLDRAGKRVRLAALVDENGVELVPERDIAYDTLVIAVGSTTNDFGTEGAAEHCIFLDTRAQAERFHRQLLGQYLRAHTGHDANNNAVSIAIIGAGATGVELAAELHHAAQMLAAYGLDRIRPEDLHISLVEAGPRVLPALPERISQPVHQTLSKLGVRVMTGSAVSKVDADGLWTGDGEFVPATLKVWAAGIRAPAFLKELDGLESNRINQLVVRPTLQTTRDDDIFAFGDCAACPQPAQPGEQPRNVPPRAQAAHQQASLLVKSLRARLEGKPLGEYHYRDYGSLISLSRFSAVGNLMGNLMGSVMLEGWLARMFYVSLYRMHQMALYGPLRTAMLMLSGRLRSTEPRLKLH
References
External Links:
Resource Link
Genome ID: PA4538
Entrez Gene ID: 878460
NCBI Protein ID: 15599734
General Reference: PaperBLAST - Find papers about PA4538 and its homologs