Dephospho-CoA kinase (PA4529)

Identification
Name: Dephospho-CoA kinase
Synonyms:
  • Dephosphocoenzyme A kinase
Gene Name: coaE
Enzyme Class:
Biological Properties
General Function: Involved in dephospho-CoA kinase activity
Specific Function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
Cellular Location: Cytoplasm (Probable)
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb ↔ Thumb+Thumb+Thumb
Adenosine triphosphate + Dephospho-CoA ↔ ADP + Coenzyme A + Hydrogen ion
ReactionCard
Thumb+Thumb ↔ Thumb+Thumb
Adenosine triphosphate + Dephospho-CoA ↔ ADP + Coenzyme A
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SMPDB Reactions:
Pantetheine 4'-phosphate+Thumb+Thumb → Thumb+Pyrophosphate
Pantetheine 4'-phosphate + Adenosine triphosphate + pantotheine 4'-phosphate → Dephospho-CoA + Pyrophosphate
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Thumb+Thumb → Adenosine diphosphate+Thumb+Thumb
Adenosine triphosphate + Dephospho-CoA → Adenosine diphosphate + Coenzyme A + ADP
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Thumb+Thumb → Thumb+Adenosine diphosphate+Thumb+Thumb
Dephospho-CoA + Adenosine triphosphate → Hydrogen ion + Adenosine diphosphate + Coenzyme A + ADP
ReactionCard
PseudoCyc/BioCyc Reactions:
Thumb+Thumb ↔ Thumb+Thumb+Thumb
Adenosine triphosphate + Dephospho-CoA ↔ ADP + Coenzyme A + Hydrogen ion
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Thumb+Thumb → Thumb+Thumb+Thumb
Dephospho-CoA + Adenosine triphosphate → Hydrogen ion + Coenzyme A + ADP
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Complex Reactions: Not Available
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB0035593'-dephospho-CoAMetaboCard
PAMDB000148Adenosine triphosphateMetaboCard
PAMDB000345ADPMetaboCard
PAMDB000381Coenzyme AMetaboCard
PAMDB000362Dephospho-CoAMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB003606pantotheine 4'-phosphateMetaboCard
GO Classification:
Function
adenyl nucleotide binding
adenyl ribonucleotide binding
ATP binding
binding
catalytic activity
dephospho-CoA kinase activity
kinase activity
nucleoside binding
purine nucleoside binding
transferase activity
transferase activity, transferring phosphorus-containing groups
Process
cellular metabolic process
coenzyme A biosynthetic process
coenzyme biosynthetic process
coenzyme metabolic process
cofactor metabolic process
metabolic process
Gene Properties
Locus tag: PA4529
Strand: +
Entrez Gene ID: 878572
Accession: NP_253219.1
GI: 15599725
Sequence start: 5073564
Sequence End: 5074175
Sequence Length: 611
Gene Sequence: 
>PA4529
ATGACCCAACCCTGGATACTAGGCCTCACGGGCGGTATCGGCAGCGGCAAGAGCGCAGCCGCCGAGCACTTCATCTCCCTCGGCGTCCACCTGGTGGACGCCGACCATGCCGCCCGCTGGGTGGTGGAGCCGGGGCGTCCGGCCCTGGCGAAGATCGTCGAACGCTTCGGCGACGGCATCCTCCTGCCCGATGGCCAGCTCGACCGCGCCGCCTTGCGCGAGCGGATCTTCCAGGCGCCGGAGGAACGGCGCTGGCTGGAGCAATTGCTGCACCCGCTGATCGGCGCGGAGATCGTCCAGTACCTGGCCAGGGCCGAATCGCCCTATGCCATCCTGGTCTCGCCGCTGCTGGTGGAGTCCGGCCAGCGCCAGATGACCCACCGCGTGCTGGTGGTGGATACCCCGGAACATCTGCAACTACAGCGCACCATGCTTCGCGACAAGGTCTCCGAGGAGCAGGTGCGCTCGATCCTCCAGGCCCAGGCCCGGCGCGACGAGCGCTTGAAGCACGCCGACGACGTGCTGGTCAACGACGGCGACCTGTCCCACCTGCAGCGTGAAGTCGAGCGACTGCACGCCTTCTACCTGACCTTGCGAGGAGGCCGAGCATGA
Protein Properties
Protein Residues: 203
Protein Molecular Weight: 22.8 kDa
Protein Theoretical pI: 6.81
Hydropathicity (GRAVY score): -0.241
Charge at pH 7 (predicted): -0.84
Protein Sequence: 
>PA4529
MTQPWILGLTGGIGSGKSAAAEHFISLGVHLVDADHAARWVVEPGRPALAKIVERFGDGILLPDGQLDRAALRERIFQAPEERRWLEQLLHPLIGAEIVQYLARAESPYAILVSPLLVESGQRQMTHRVLVVDTPEHLQLQRTMLRDKVSEEQVRSILQAQARRDERLKHADDVLVNDGDLSHLQREVERLHAFYLTLRGGRA
References
External Links:
Resource Link
Genome ID: PA4529
Entrez Gene ID: 878572
NCBI Protein ID: 15599725
General Reference: PaperBLAST - Find papers about PA4529 and its homologs