3,4-dihydroxy-2-butanone 4-phosphate synthase (PA4054)

Identification
Name: 3,4-dihydroxy-2-butanone 4-phosphate synthase
Synonyms:
  • DHBP synthase
Gene Name: ribB
Enzyme Class:
Biological Properties
General Function: Involved in 3,4-dihydroxy-2-butanone-4-phosphate synthase activity
Specific Function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Cellular Location: Cell membrane; Peripheral membrane protein (Potential)
KEGG Pathways:
KEGG Reactions:
Thumb ↔ Thumb+Thumb+Thumb
D-Ribulose 5-phosphate ↔ 3,4-Dihydroxy-2-butanone-4-P + Formic acid + Hydrogen ion
ReactionCard
D-Ribulose 5-phosphate ↔ Thumb+Thumb
D-Ribulose 5-phosphate ↔ 3,4-Dihydroxy-2-butanone-4-P + Formic acid
ReactionCard
SMPDB Reactions:
Thumb → Thumb+Thumb+Thumb
D-Ribulose 5-phosphate → Formic acid + Hydrogen ion + 1-Deoxy-L-glycero-tetrulose 4-phosphate
ReactionCard
PseudoCyc/BioCyc Reactions:
Thumb ↔ Thumb+Thumb+Thumb
D-Ribulose 5-phosphate ↔ 3,4-Dihydroxy-2-butanone-4-P + Formic acid + Hydrogen ion
ReactionCard
Complex Reactions:
Thumb → Thumb+Thumb
D-Ribulose 5-phosphate → Formic acid + 1-Deoxy-L-glycero-tetrulose 4-phosphate
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB0035121-Deoxy-L-glycero-tetrulose 4-phosphateMetaboCard
PAMDB0005903,4-Dihydroxy-2-butanone-4-PMetaboCard
PAMDB000638D-Ribulose 5-phosphateMetaboCard
PAMDB000053Formic acidMetaboCard
PAMDB001633Hydrogen ionMetaboCard
GO Classification:
Function
3,4-dihydroxy-2-butanone-4-phosphate synthase activity
carbon-carbon lyase activity
catalytic activity
lyase activity
Process
metabolic process
nitrogen compound metabolic process
riboflavin biosynthetic process
riboflavin metabolic process
Gene Properties
Locus tag: PA4054
Strand: -
Entrez Gene ID: 878914
Accession: NP_252743.1
GI: 15599249
Sequence start: 4534710
Sequence End: 4535807
Sequence Length: 1097
Gene Sequence: 
>PA4054
ATGGCACTCAACACGATCGACGAACTGATCGAAGACATCCGCCAAGGCAAGATGGTCATCCTGATGGATGACGAGGACCGCGAGAACGAAGGCGACCTGATCATGGCCGCCGAATGCGTCCGCACCGAAGACATCAACTTCATGGTCAAGCATGCCCGCGGCCTGGTCTGCATGCCGATGACCCGCGAGCGTTGCGAGCGCCTCGGCCTGCCGCTGATGGTGCAGCGCAACGGCTCCGGCTTCGGCACCAAGTTCACTGTCTCCATCGAGGCCGCCGAGGGCGTCACCACCGGCATCTCCGCCGCGGACCGCGCCCGCACCGTGCAGGCTGCGGCGGCGAAGAACGCCGTGGCCGCCGACATCGTCAGCCCCGGCCACATCTTCCCGCTGATGGCCCAGCCGGGCGGTACCCTGGCTCGCGCCGGGCACACCGAGGCGGCCTGCGACCTGGCGCGGATGGCCGGGTTCGAGCCGTCCGGGGTGATCTGCGAGGTGATGAACGACGACGGCAGCATGGCTCGCCGGCCCGAACTGGAGGCGTTCGCCGCCGAGCACGGGATCAAGATCGGCACCATCGCCGACCTGATCCACTACCGGCTGATCCACGAGCGCACCGTCGAGCGCATCGCCGAGCAGCCGCTCGACAGCGAACTGGGCCACTTCAACCTGATCACCTACCGCGACTCGGTGGAGGGCGACGTGCACCTGGCGCTGACCCTCGGCAAGGTCTGCGCGGAAGAGCCGACCTTGGTCCGCGTGCATAACATGGACCCGCTGCGCGACCTGCTGCAGGTCAACCAACCGGGCCGCTGGAGCCTGCGCGCGGCGATGACCAAGGTCGCCGAGGCGGGCAGCGGCGTGGTGCTGCTGCTCGGTCACCAGATCGGCGGCGACGACCTGCTCGCCCATGTCCGCGAGATCGCTTCGGCGCCGGCTCCGGCGCCCAAGGCCACCACCACCTACAGCACCGTCGGTGCCGGTTCGCAGATCCTGCGCGACCTCGGCGTGCGCAAGATGCGCCTGCTGAGTGCGCCGATGCGCTTCAATGCGATATCCGGTTTCGACCTGGAAGTTGTAGAATACCTGCCCGCCGAATAA
Protein Properties
Protein Residues: 365
Protein Molecular Weight: 39.4 kDa
Protein Theoretical pI: 5.05
Hydropathicity (GRAVY score): -0.017
Charge at pH 7 (predicted): -12.52
Protein Sequence: 
>PA4054
MALNTIDELIEDIRQGKMVILMDDEDRENEGDLIMAAECVRTEDINFMVKHARGLVCMPMTRERCERLGLPLMVQRNGSGFGTKFTVSIEAAEGVTTGISAADRARTVQAAAAKNAVAADIVSPGHIFPLMAQPGGTLARAGHTEAACDLARMAGFEPSGVICEVMNDDGSMARRPELEAFAAEHGIKIGTIADLIHYRLIHERTVERIAEQPLDSELGHFNLITYRDSVEGDVHLALTLGKVCAEEPTLVRVHNMDPLRDLLQVNQPGRWSLRAAMTKVAEAGSGVVLLLGHQIGGDDLLAHVREIASAPAPAPKATTTYSTVGAGSQILRDLGVRKMRLLSAPMRFNAISGFDLEVVEYLPAE
References
External Links:
Resource Link
Genome ID: PA4054
Entrez Gene ID: 878914
NCBI Protein ID: 15599249
General Reference: PaperBLAST - Find papers about PA4054 and its homologs