Inorganic pyrophosphatase (PA4031)

Identification
Name: Inorganic pyrophosphatase
Synonyms:
  • Pyrophosphate phospho-hydrolase
  • PPase
Gene Name: ppa
Enzyme Class:
Biological Properties
General Function: Involved in magnesium ion binding
Specific Function: Diphosphate + H(2)O = 2 phosphate
Cellular Location: Cytoplasm
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb ↔ Thumb
Pyrophosphate + Water ↔ Phosphate
ReactionCard
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
Thumb+Thumb → Thumb+2 Thumb
Water + Pyrophosphate → Hydrogen ion + 2 Phosphate
ReactionCard
Complex Reactions:
Thumb+Thumb → 2 Thumb
Pyrophosphate + Water → 2 Inorganic phosphate
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB001633Hydrogen ionMetaboCard
PAMDB001776Inorganic phosphateMetaboCard
PAMDB000383PhosphateMetaboCard
PAMDB000633PyrophosphateMetaboCard
PAMDB000142WaterMetaboCard
GO Classification:
Component
cell part
cytoplasm
intracellular part
Function
binding
catalytic activity
cation binding
hydrolase activity
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
inorganic diphosphatase activity
ion binding
magnesium ion binding
metal ion binding
pyrophosphatase activity
Process
cellular metabolic process
metabolic process
phosphate metabolic process
phosphorus metabolic process
Gene Properties
Locus tag: PA4031
Strand: +
Entrez Gene ID: 879025
Accession: NP_252720.1
GI: 15599226
Sequence start: 4512549
Sequence End: 4513076
Sequence Length: 527
Gene Sequence: 
>PA4031
ATGAGCTACAGCAAGATCCCGGCCGGCAAGGACCTGCCGAACGACATCTACGTCGCTATCGAGATTCCGGCCAACCATGCGCCGATCAAGTACGAGATCGACAAGGACACCGACTGCCTGTTCGTCGACCGTTTCATGGCCACCCCGATGTTCTACCCGGCCAACTACGGCTTCATCCCGAACACTCTGGCCGACGACGGCGACCCGCTGGACGTGCTGGTGGTGACCCCCTATCCGGTCGCTCCCGGTTCGGTGATCCGCGCGCGCCCGGTTGGCGTCCTGCACATGACCGACGAGGCAGGCGGCGACGCCAAGCTGATCGCCGTGCCGCACGACAAGCTGAGCGTCCTGTACAAGGACGTGAAGGAATACACCGACCTGCCGGCCCTGCTGCTGGAACAGATCAAGCACTTCTTCGAGAACTACAAGGATCTCGAGAAAGGCAAGTGGGTCAAGGTCGAAGGCTGGGGCAACGCCGACGCCGCCCGCGCCGAGATCACCAAGGCCGTGGCCGCGTTCCAGAAGTAA
Protein Properties
Protein Residues: 175
Protein Molecular Weight: 19.4 kDa
Protein Theoretical pI: 4.86
Hydropathicity (GRAVY score): -0.142
Charge at pH 7 (predicted): -6.08
Protein Sequence: 
>PA4031
MSYSKIPAGKDLPNDIYVAIEIPANHAPIKYEIDKDTDCLFVDRFMATPMFYPANYGFIPNTLADDGDPLDVLVVTPYPVAPGSVIRARPVGVLHMTDEAGGDAKLIAVPHDKLSVLYKDVKEYTDLPALLLEQIKHFFENYKDLEKGKWVKVEGWGNADAARAEITKAVAAFQK
References
External Links:
Resource Link
Genome ID: PA4031
Entrez Gene ID: 879025
NCBI Protein ID: 15599226
General Reference: PaperBLAST - Find papers about PA4031 and its homologs