Uridylate kinase (PA3654)

Identification
Name: Uridylate kinase
Synonyms:
  • UK
  • Uridine monophosphate kinase
  • UMP kinase
  • UMPK
Gene Name: pyrH
Enzyme Class:
Biological Properties
General Function: Involved in cellular amino acid biosynthetic process
Specific Function: Catalyzes the reversible phosphorylation of UMP to UDP, with ATP as the most efficient phosphate donor
Cellular Location: Cytoplasm.
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb ↔ Thumb+Thumb
Adenosine triphosphate + Uridine 5'-monophosphate ↔ ADP + Uridine 5'-diphosphate
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Thumb+Thumb ↔ Thumb+Thumb
Adenosine triphosphate + Uridine 5'-monophosphate ↔ ADP + Uridine 5'-diphosphate
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SMPDB Reactions:
Thumb+Thumb → Adenosine diphosphate+Uridine 5'-diphosphate+Thumb+Thumb
Uridine 5'-monophosphate + Adenosine triphosphate → Adenosine diphosphate + Uridine 5'-diphosphate + ADP + Uridine 5'-diphosphate
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PseudoCyc/BioCyc Reactions:
Thumb+Thumb ↔ Thumb+Thumb
Adenosine triphosphate + Uridine 5'-monophosphate ↔ ADP + Uridine 5'-diphosphate
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Thumb+Thumb ↔ Thumb+Thumb
Adenosine triphosphate + Uridine 5'-monophosphate ↔ ADP + Uridine 5'-diphosphate
ReactionCard
Complex Reactions:
Thumb+Thumb → Thumb+Thumb
Adenosine triphosphate + Uridine 5'-monophosphate → ADP + Uridine 5'-diphosphate
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Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000148Adenosine triphosphateMetaboCard
PAMDB000345ADPMetaboCard
PAMDB000123Uridine 5'-diphosphateMetaboCard
PAMDB000118Uridine 5'-monophosphateMetaboCard
GO Classification:
Component
cell part
cytoplasm
intracellular part
Function
catalytic activity
phosphotransferase activity, phosphate group as acceptor
transferase activity
transferase activity, transferring phosphorus-containing groups
UMP kinase activity
uridylate kinase activity
Process
cellular amino acid and derivative metabolic process
cellular amino acid biosynthetic process
cellular amino acid metabolic process
cellular metabolic process
cellular nitrogen compound metabolic process
metabolic process
nitrogen compound metabolic process
nucleobase, nucleoside and nucleotide metabolic process
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
nucleoside phosphate metabolic process
nucleotide metabolic process
pyrimidine nucleotide biosynthetic process
pyrimidine nucleotide metabolic process
Gene Properties
Locus tag: PA3654
Strand: -
Entrez Gene ID: 880536
Accession: NP_252344.1
GI: 15598850
Sequence start: 4092231
Sequence End: 4092968
Sequence Length: 737
Gene Sequence: 
>PA3654
ATGGCTCAGCAACTGAGCGCTCGTCAACCTCGCTATAAACGCATTCTTCTAAAGTTGAGCGGCGAAGCCCTGATGGGCTCGGAGGAGTTCGGCATTGATCCCAAGGTGCTGGACCGCATGGCGCTGGAAATCGGCCAGTTGGTCGGGATCGGCGTGCAGGTCGGCCTGGTCATCGGCGGCGGCAACCTGTTCCGCGGCGCGGCCCTGTCCGCGGCCGGCATGGACCGGGTGACCGGCGACCACATGGGGATGCTGGCCACCGTGATGAACGGCCTGGCGATGCGCGATGCGCTGGAGCGCTCGAACATCCCCGCGCTGGTGATGTCGGCGATCTCCATGGTCGGTGTGACCGACCACTACGACCGCCGCAAGGCCATGCGCCACCTCGGCGGTGGCGAGGTGGTGATCTTCTCCGCCGGTACCGGCAACCCGTTCTTCACCACCGACTCGGCGGCTTGCCTGCGCGCCATCGAGATCGACGCCGACGTGGTCCTTAAGGCTACCAAGGTCGATGGCGTGTACACTGCCGACCCGTTCAAGGACCCGAATGCCGAGAAGTTCGAGCGCCTGACCTATGATGAAGTGCTCGACCGCAAGCTCGGCGTGATGGACCTGACCGCCATCTGCCTGTGCCGTGACCAGAACATGCCGCTGCGGGTGTTCAACATGAACAAGCCGGGCGCATTGCTGAATATTGTTGTTGGTGGTGCCGAAGGCACCCTGATCGAGGAGGGTTGA
Protein Properties
Protein Residues: 245
Protein Molecular Weight: 26.3 kDa
Protein Theoretical pI: 5.38
Hydropathicity (GRAVY score): 0.117
Charge at pH 7 (predicted): -3.37
Protein Sequence: 
>PA3654
MAQQLSARQPRYKRILLKLSGEALMGSEEFGIDPKVLDRMALEIGQLVGIGVQVGLVIGGGNLFRGAALSAAGMDRVTGDHMGMLATVMNGLAMRDALERSNIPALVMSAISMVGVTDHYDRRKAMRHLGGGEVVIFSAGTGNPFFTTDSAACLRAIEIDADVVLKATKVDGVYTADPFKDPNAEKFERLTYDEVLDRKLGVMDLTAICLCRDQNMPLRVFNMNKPGALLNIVVGGAEGTLIEEG
References
External Links:
Resource Link
Genome ID: PA3654
Entrez Gene ID: 880536
NCBI Protein ID: 15598850
General Reference: PaperBLAST - Find papers about PA3654 and its homologs