P. aeruginosa Metabolome Database Protein PA3416

Identification

Name:

probable pyruvate dehydrogenase E1 component, beta chain

Synonyms:

Not Available

Gene Name:

Not Available

Enzyme Class:

Not Available

Biological Properties

General Function:

metabolic process

Specific Function:

catalytic activity

Cellular Location:

Not Available

KEGG Pathways:

superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass GLYCOLYSIS-TCA-GLYOX-BYPASS
pyruvate fermentation to acetate and lactate I P41-PWY
pyruvate decarboxylation to acetyl CoA PYRUVDEHYD-PWY
anaerobic respiration ANARESP1-PWY
pyruvate fermentation to acetate II PWY-5482
lactate oxidation LCTACACAT-PWY

KEGG Reactions:

Not Available

SMPDB Reactions:

Not Available

PseudoCyc/BioCyc Reactions:

Ubiquinones

→

Ubiquinols

pyruvate + Water + Ubiquinones → Carbon dioxide + Ubiquinols + acetate
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glycine + a tetrahydrofolate + NAD⁺ → a 5,10-methylene-tetrahydrofolate + ammonium + CO₂ + NADH
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pyruvate + coenzyme A + NAD⁺ → acetyl-CoA + CO₂ + NADH
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pyruvate + lipoamide → S-acetyldihydrolipoamide + CO₂
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acetyl-CoA + dihydrolipoamide ← S-acetyldihydrolipoamide + coenzyme A
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2-oxoglutarate + coenzyme A + NAD⁺ → succinyl-CoA + CO₂ + NADH
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a [glycine-cleavage complex H protein] N⁶-aminomethyldihydrolipoyl-L-lysine + a tetrahydrofolate ↔ a [glycine-cleavage complex H protein] N⁶-dihydrolipoyl-L-lysine + a 5,10-methylene-tetrahydrofolate + ammonium
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glycine + a [glycine-cleavage complex H protein] N⁶-lipoyl-L-lysine + H⁺ ↔ a [glycine-cleavage complex H protein] N⁶-aminomethyldihydrolipoyl-L-lysine + CO₂
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succinyl-lipoate + coenzyme A → succinyl-CoA + DIHYDROLIPOYL-OXO-GLUT-E2
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a [lipoyl-carrier protein] N⁶-dihydrolipoyl-L-lysine + NAD⁺ = a [lipoyl-carrier protein]-N⁶-lipoyl-L-lysine + NADH + H⁺
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2-oxoglutarate + a [2-oxoglutarate dehydrogenase E2 protein] N⁶-lipoyl-L-lysine + H⁺ → a [2-oxoglutarate dehydrogenase E2 protein] N⁶-S-succinyldihydrolipoyl-L-lysine + CO₂
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pyruvate + a [pyruvate dehydrogenase E2 protein] N⁶-lipoyl-L-lysine + H⁺ → a [pyruvate dehydrogenase E2 protein] N⁶-S-acetyldihydrolipoyl-L-lysine + CO₂
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acetyl-CoA + a [pyruvate dehydrogenase E2 protein] N⁶-dihydrolipoyl-L-lysine ← a [pyruvate dehydrogenase E2 protein] N⁶-S-acetyldihydrolipoyl-L-lysine + coenzyme A
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a [pyruvate dehydrogenase E2 protein] N⁶-dihydrolipoyl-L-lysine + NAD⁺ → a [pyruvate dehydrogenase E2 protein] N⁶-lipoyl-L-lysine + NADH + H⁺
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→

acetate + Carbon dioxide + Hydrogen ion → pyruvate + Water
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Complex Reactions:

Not Available

Transports:

Not Available

Metabolites:

Not Available

GO Classification:

Function
catalytic activity
Process
metabolic process

Gene Properties

Locus tag:

PA3416

Strand:

Entrez Gene ID:

878692

Accession:

NP_252106.1

GI:

15598612

Sequence start:

3822515

Sequence End:

3823516

Sequence Length:

1001

Gene Sequence:

>PA3416
ATGAATGAGCGCAACGGCGAAGCGAAACGCCTGGCCCTTCTGGAGGCGGTCAACCTGGCGTTGCACCGGGCCATGGCCGAGGACGAGACGGTGGTGGTGCTGGGCGAAGACGTCGGGGTCAACGGCGGGGTGTTTCGCGCCACCCTCGGCCTGCGCGAGCGCTTCGGCTTCAAGCGGGTGCTGGATACGCCGCTGGCGGAGAACATGATCGCCGGGCTGTCCATCGGCATGGCCGCCCAGGGCCTGAAGCCGGTGATGGAGATCCAGTTCATGGGCTTCATCTACGCCGCCATGGAGCAACTGGTGTCCCATGCCAGCCGCCTGCGCAATCGCACCCGCGGCCGCCTGGCCTGCCCGTTGGTGCTGCGCACGCCGATGGGCGCGGGGATCCGCGCGCCGGAGCACCACAGCGAGGCGACCGAGGCGATGTTCGCGCACATCCCCGGCGTCCGCGTGCTGGTGCCGTCGTCGCCGGCGCGGGCCTACGGCCTGCTCCTGGCGGCGATCGACGATCCCGATCCGGTGATCTTCCTCGAGCCGACCCGGCTCTACCGGATGAACCCGCAGCCGCTGGCGGACGACGCCCGGCGCCTGCCGCTGGACAGTTGCTTCACCCTTCGCGAAGGCGGCGACCTGACCCTGGTCAGCTGGGGCGCCAGCGTCCACGAGACCCAGCAGGCCGCCGAGCGCCTGGCGCAGCGCGGCATCGAGGCCGAAGTGATCGACGTCGCCTGCCTCAAGCCGCTCGACCTCGACACCCTCGAAGCTTCGGTGCGCAAGACCGGTCGCTGCGTGATCGTCCATGAGGCGCCGAAGAGCGGCGGCCTTGGCGGGGAAATCGCCGCGAGCCTCTACGAGCGCGTCCTGTTCGATCTGCGGGCGCCGATCCAGCGGGTCGCCGCGGCCGATATCCCGCCGCCGCTGTACCGCCTGGAACCGCTGTACATGCCCGCCGTGGAGGACATCCTGGCGGCCTGCGACACCGTGCTCGGCTACGCCTGA

Protein Properties

Protein Residues:

333

Protein Molecular Weight:

36.1 kDa

Protein Theoretical pI:

5.68

Hydropathicity (GRAVY score):

0.083

Charge at pH 7 (predicted):

-5.46

Protein Sequence:

>PA3416
MNERNGEAKRLALLEAVNLALHRAMAEDETVVVLGEDVGVNGGVFRATLGLRERFGFKRVLDTPLAENMIAGLSIGMAAQGLKPVMEIQFMGFIYAAMEQLVSHASRLRNRTRGRLACPLVLRTPMGAGIRAPEHHSEATEAMFAHIPGVRVLVPSSPARAYGLLLAAIDDPDPVIFLEPTRLYRMNPQPLADDARRLPLDSCFTLREGGDLTLVSWGASVHETQQAAERLAQRGIEAEVIDVACLKPLDLDTLEASVRKTGRCVIVHEAPKSGGLGGEIAASLYERVLFDLRAPIQRVAAADIPPPLYRLEPLYMPAVEDILAACDTVLGYA

References

External Links:

Resource	Link
Genome ID:	PA3416
Entrez Gene ID:	878692
NCBI Protein ID:	15598612

General Reference:

PaperBLAST - Find papers about PA3416 and its homologs

probable pyruvate dehydrogenase E1 component, beta chain (PA3416)