Identification
Name: Alkaline phosphatase
Synonyms:
  • APase
Gene Name: phoA
Enzyme Class:
Biological Properties
General Function: Involved in catalytic activity
Specific Function: A phosphate monoester + H(2)O = an alcohol + phosphate
Cellular Location: Periplasm
KEGG Pathways:
KEGG Reactions:
Thumb+3 ThumbThumb+3 Thumb
Thumb+ThumbAlcohol+Thumb
SMPDB Reactions:
Thumb+ThumbThumb+Thumb
Thumb+ThumbThumb+Thumb
Thumb+ThumbThumb+Thumb
PseudoCyc/BioCyc Reactions:
Thumb+ThumbThumb+Thumb
Thumb+3 ThumbThumb+3 Thumb
A phosphate monoester+Thumban alcohol+Thumb
A phosphate monoester + Water → an alcohol + Inorganic phosphate
ReactionCard
Thumb+ThumbAlcohol+Thumb
Thumb+ThumbThumb+Thumb
Thumb
a phosphate monoester + a phosphate monoester + H2O → an alcohol + phosphate
ReactionCard
PAMDB120448+PAMDB000142PAMDB110244+PAMDB000041
Complex Reactions:
Thumb+ThumbThumb+Thumb
A phosphate monoester+Thumban alcohol+Thumb
A phosphate monoester + Water → an alcohol + Inorganic phosphate
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB0003054-NitrophenolMetaboCard
PAMDB0063004-nitrophenylphosphateMetaboCard
PAMDB0004547,8-DihydroneopterinMetaboCard
PAMDB000016AdenosineMetaboCard
PAMDB000014Adenosine monophosphateMetaboCard
PAMDB000274Dihydroneopterin triphosphateMetaboCard
PAMDB000355Hydrogen (gas)MetaboCard
PAMDB001776Inorganic phosphateMetaboCard
PAMDB000197NADMetaboCard
PAMDB000089NADPMetaboCard
PAMDB000383PhosphateMetaboCard
PAMDB001286PhosphonateMetaboCard
PAMDB000142WaterMetaboCard
GO Classification:
Function
catalytic activity
hydrolase activity
hydrolase activity, acting on ester bonds
phosphatase activity
phosphoric ester hydrolase activity
Process
metabolic process
Gene Properties
Locus tag: PA3296
Strand: +
Entrez Gene ID: 882459
Accession: NP_251986.1
GI: 15598492
Sequence start: 3689521
Sequence End: 3690951
Sequence Length: 1430
Gene Sequence:
>PA3296
ATGACCCCAGGTTATCCCCTCGCCCTCTCTCTTGCCGTCTCCATGGCCGTGCTCGGCAGCGCCTTGCCGGCCCAGGCGCGCCAGGACGATCCGTCACTGTTCAACCGCCAGGCCCGTGGCGAACTCAGCGAGTACGGCGGCGCACGGCGCGTCGAGCAGGACCTGACCCAGGCCCTGAAGCAGTCGCTGTCGAAGAAGAAGGCGAAGAACGTGATCCTGCTGATCGGCGACGGCATGGGCGACTCCGAGATCACCGTGGCGCGCAACTACGCGCGCGGCGCGGGCGGCTACTTCAAGGGTATCGATGCGCTGCCGCTGACCGGTCAGTACACCCACTACTCCCTGCACAAGGACAGCGGCCTGCCGGACTACGTGACCGATTCCGCCGCCTCCGCCACCGCCTGGTCCACCGGGGTCAAGTCGTACAACGGCGCGATCGGCGTGGATATCCACGAACAGCCGCACCGCAACCTGCTGGAGCTGGCCAAGCTCAACGGCAAGGCCACCGGCAACGTCTCCACCGCCGAGCTGCAGGACGCCACCCCCGCCGCCCTGCTCGCCCACGTCACCGCTCGCAAGTGCTACGGTCCCGAGGCCACCAGCAAGCAGTGCCCGAGCAATGCCCTGGAGAACGGCGGCGCCGGCTCGATCACCGAGCAGTGGCTGAAGACCCGCCCTGACGTGGTTCTCGGCGGCGGCGCCGCGACCTTCGCGGAAACCGCCAAGGCTGGCCGCTATGCCGGCAAGACCCTCCGCGCCCAGGCCGAAGCCCGCGGCTACCGGATCGTCGAGAACCTCGACGAGCTGAAAGCCGTGCGCCGCGCCAACCAGAAGCAGCCGCTGATCGGCCTGTTCGCGCCGGGCAACATGCCAGTGCGCTGGCTCGGTCCGACCGCCACCTACCACGGCAACCTGAACCAGCCGGCGGTGAGCTGCGAGGCGAACCCGAAGCGCACCGCCGACATCCCGACCCTGGCGCAAATGACCAGCAAGGCCATCGAGCTGCTGAAGGACAATCCGAACGGCTTCTTCCTGCAGGTCGAGGGCGCGTCCATCGACAAGCAGGACCATGCCGCGAATCCGTGCGGCCAGATCGGCGAGACCGTCGACCTCGACGAAGCCGTGCAGAAGGCCCTGGCCTTTGCCAAGGCCGATGGCGAGACCCTGGTGATCGTCACCGCCGACCACGCCCACTCCAGCCAGATCATCCCGCCGGAAACCGCCGCGCCGGGGCTGACCCAACTGCTCACGACCAAGGACGGCGCGCCGCTGGCGATCAGCTACGGCAACTCCGAGGAAAGCTCCCAGGAGCACACCGGCACCCAGTTGCGCATCGCCGCCTACGGCCCGCAGGCCGCCAATGTCACCGGCCTGACCGACCAGACCGACCTGTTCTTCACCATCCGTCGCGCACTGAACCTGCGCGACTGA
Protein Properties
Protein Residues: 476
Protein Molecular Weight: 50.4 kDa
Protein Theoretical pI: 6.86
Hydropathicity (GRAVY score): -0.329
Charge at pH 7 (predicted): -0.71
Protein Sequence:
>PA3296
MTPGYPLALSLAVSMAVLGSALPAQARQDDPSLFNRQARGELSEYGGARRVEQDLTQALKQSLSKKKAKNVILLIGDGMGDSEITVARNYARGAGGYFKGIDALPLTGQYTHYSLHKDSGLPDYVTDSAASATAWSTGVKSYNGAIGVDIHEQPHRNLLELAKLNGKATGNVSTAELQDATPAALLAHVTARKCYGPEATSKQCPSNALENGGAGSITEQWLKTRPDVVLGGGAATFAETAKAGRYAGKTLRAQAEARGYRIVENLDELKAVRRANQKQPLIGLFAPGNMPVRWLGPTATYHGNLNQPAVSCEANPKRTADIPTLAQMTSKAIELLKDNPNGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQKALAFAKADGETLVIVTADHAHSSQIIPPETAAPGLTQLLTTKDGAPLAISYGNSEESSQEHTGTQLRIAAYGPQAANVTGLTDQTDLFFTIRRALNLRD
References
External Links:
Resource Link
Genome ID: PA3296
Entrez Gene ID: 882459
NCBI Protein ID: 15598492
General Reference: PaperBLAST - Find papers about PA3296 and its homologs