Glyoxylate carboligase (PA1502)

Identification
Name: Glyoxylate carboligase
Synonyms:
  • Tartronate-semialdehyde synthase
Gene Name: gcl
Enzyme Class:
Biological Properties
General Function: Involved in tartronate-semialdehyde synthase activity
Specific Function: Catalyzes the condensation of two molecules of glyoxylate to give 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde)
Cellular Location: Not Available
KEGG Pathways:
KEGG Reactions:
2 Thumb+Thumb ↔ Thumb+Thumb
2 Glyoxylic acid + Hydrogen ion ↔ Tartronate semialdehyde + Carbon dioxide
ReactionCard
2 Thumb ↔ Thumb+Thumb
2 Glyoxylic acid ↔ Tartronate semialdehyde + Carbon dioxide
ReactionCard
SMPDB Reactions:
2 Thumb+Thumb → Thumb+Thumb
2 Glyoxylic acid + Hydrogen ion → Carbon dioxide + Tartronate semialdehyde
ReactionCard
PseudoCyc/BioCyc Reactions:
2 Thumb+Thumb ↔ Thumb+Thumb
2 Glyoxylic acid + Hydrogen ion ↔ Tartronate semialdehyde + Carbon dioxide
ReactionCard
Complex Reactions:
2 Thumb → Thumb+Thumb
2 Glyoxylic acid → Tartronate semialdehyde + Carbon dioxide
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000568Carbon dioxideMetaboCard
PAMDB000043Glyoxylic acidMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB000707Tartronate semialdehydeMetaboCard
GO Classification:
Function
binding
carbon-carbon lyase activity
carboxy-lyase activity
catalytic activity
cation binding
ion binding
lyase activity
magnesium ion binding
metal ion binding
tartronate-semialdehyde synthase activity
thiamin pyrophosphate binding
vitamin binding
Process
aldehyde catabolic process
cellular aldehyde metabolic process
cellular metabolic process
glyoxylate catabolic process
metabolic process
Gene Properties
Locus tag: PA1502
Strand: -
Entrez Gene ID: 879454
Accession: NP_250193.1
GI: 15596699
Sequence start: 1630902
Sequence End: 1632677
Sequence Length: 1775
Gene Sequence: 
>PA1502
ATGGCCAGAATGAGAGCAATCGAAGCCGCCGTACTGGTGATGCGCCGCGAAGGCGTGGATACCGCGTTCGGCGTCCCCGGTGCCGCGATCAACCCCATGTACGCCGCGCTGAAGAAGATCGGCGGCATCGACCATGTCCTGGCCCGTCACGTCGAAGGCGCCTCGCACATGGCCGAGGGCTACACCCGTACCAAGGCCGGCAACATCGGCGTCTGCATCGGCACCTCCGGCCCTGCCGGCACCGACATGATCACCGGCCTCTACTCCGCCTCCGCCGACTCCATCCCGATTCTCTGCATTACCGGCCAGGCACCGCGCGCCCGCCTGCACAAGGAAGACTTCCAGGCGGTCGACATCTCCAGCATCGCCGCGCCGGTGGCCAAGTGGGCGACCACCGTGCTGGAACCGGCCCAGGTCCCCTATGTATTCCAGAAGGCCTTCCAGCTGATGCGCAGCGACCGGCCCGGCCCGGTACTGATCGACCTGCCGTTCGACGTACAGATGGCCGAGATCGAGTTCGACATCGACGCCTACGAGCCCCTCCCGGTGAGCAAGCCGAAGGCCACCCGGGTCCAGGCCGAGAAGGTCCTGGCCATGCTCGACGAAGCCGAGCGCCCGCTGCTGGTGGCCGGCGGCGGCATCTTCAACGCCGACGCCGCCGAGCGCTTCCGCGAATTCGCCGAGCTGACCGGCATCCCGGTGATCCCGACCCTGATGGGCTGGGGCGTAATCCCCGACGACCACCCGCAGATGGCCGGCATGGTCGGCCTGCAGACCTCGCACCGCTACGGCAACGCCACCCTGCTGGAATCCGACCTGGTGCTCGGCATCGGCAACCGCTGGGCCAACCGCCACACCGGCAGCGTCGAGGTCTATACCGAAGGTCGCCGCTTCATCCATGTCGACATCGAACCGACCCAGATCGGCCGGGTGTTCATGCCCGACCTGGGCATCGTCTCCGACGCCGGCGCCGCCCTCGACGCATTCCTCGAAGTGGCCCGCGAGTGGAAGGCCGCCGGCAAGCTGAAGTCGCGCGCCGCCTGGCTGGAAAGCTGCCAGCAGCGCAAACGCACGCTGCAGCGCAAGACCCACTTCGACAACGTGCCGGTGAAACCGCAGCGCGTCTACGAAGAGATGAACGAGTTCTTCGGCAAGGATGCCTGCTACGTCAGCACCATCGGCCTGTCGCAGATCGCCGGCGCACAGTTCCTCCATGTCTACCAGCCGCGCCACTGGATCAACTGCGGCCAGGCCGGCCCGCTGGGCTGGACCATTCCCGCCGCGCTGGGAGTGGTCAAGGCCGACCCGAGCCGCCAGGTGGTGGCGCTCTCCGGCGACTACGACTTCCAGTTCATGATCGAGGAACTGGCGGTCGGCGCGCAGTTCAAGCTGCCCTATATCCACGTACTGGTGAACAACTCCTACCTGGGCCTGATCCGCCAGGCGCAGCGCGGCTTCGACATGGACTATTGCGTGCAGCTGGCCTTCGACAACATCAACGCCCCCGAGCTGGAAGGCTACGGCGTCGACCACGTCGCGGTGGTCGAGGGCCTGGGCTGCAAGGCGATCCGGGTGTTCGACCCGAACGAGATCGGCGCCGCCCTGGCCAAGGCCCGCGAACTGATGCAGCAGCACCAGGTGCCGGTGGTGGTCGAGGTGATCCTGGAGCGCATCACCAACATCTCCATGGGTACCGAGATCAACGCCATCAACGAGTTCGAGGAACTGGCCGAGAAAGGCGCCGACGCGCCGACCGCCATCTCGCTGCTCGACTGA
Protein Properties
Protein Residues: 591
Protein Molecular Weight: 64.4 kDa
Protein Theoretical pI: 5.27
Hydropathicity (GRAVY score): 0.016
Charge at pH 7 (predicted): -13.82
Protein Sequence: 
>PA1502
MARMRAIEAAVLVMRREGVDTAFGVPGAAINPMYAALKKIGGIDHVLARHVEGASHMAEGYTRTKAGNIGVCIGTSGPAGTDMITGLYSASADSIPILCITGQAPRARLHKEDFQAVDISSIAAPVAKWATTVLEPAQVPYVFQKAFQLMRSDRPGPVLIDLPFDVQMAEIEFDIDAYEPLPVSKPKATRVQAEKVLAMLDEAERPLLVAGGGIFNADAAERFREFAELTGIPVIPTLMGWGVIPDDHPQMAGMVGLQTSHRYGNATLLESDLVLGIGNRWANRHTGSVEVYTEGRRFIHVDIEPTQIGRVFMPDLGIVSDAGAALDAFLEVAREWKAAGKLKSRAAWLESCQQRKRTLQRKTHFDNVPVKPQRVYEEMNEFFGKDACYVSTIGLSQIAGAQFLHVYQPRHWINCGQAGPLGWTIPAALGVVKADPSRQVVALSGDYDFQFMIEELAVGAQFKLPYIHVLVNNSYLGLIRQAQRGFDMDYCVQLAFDNINAPELEGYGVDHVAVVEGLGCKAIRVFDPNEIGAALAKARELMQQHQVPVVVEVILERITNISMGTEINAINEFEELAEKGADAPTAISLLD
References
External Links:
Resource Link
Genome ID: PA1502
Entrez Gene ID: 879454
NCBI Protein ID: 15596699
General Reference: PaperBLAST - Find papers about PA1502 and its homologs