Identification |
Name: |
Alpha-ribazole phosphatase |
Synonyms: |
- Alpha-ribazole-5'-phosphate phosphatase
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Gene Name: |
cobC |
Enzyme Class: |
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Biological Properties |
General Function: |
Involved in catalytic activity |
Specific Function: |
Converts N1-(5-phospho-alpha-D-ribosyl)-5,6- dimethylbenzimidazole into N1-alpha-D-ribosyl-5,6- dimethylbenzimidazole; involved in the assembly of the nucleotide loop of cobalamin |
Cellular Location: |
Cytoplasmic |
KEGG Pathways: |
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KEGG Reactions: |
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SMPDB Reactions: |
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PseudoCyc/BioCyc Reactions: |
| | | | |
adenosylcobalamin 5'-phosphate | + | | → | | + | |
| |
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Complex Reactions: |
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Transports: |
Not Available |
Metabolites: |
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GO Classification: |
Function |
---|
alpha-ribazole phosphatase activity | catalytic activity | hydrolase activity | hydrolase activity, acting on ester bonds | phosphatase activity | phosphoric ester hydrolase activity | Process |
---|
cobalamin biosynthetic process | metabolic process | nitrogen compound metabolic process | porphyrin biosynthetic process | porphyrin metabolic process | tetrapyrrole metabolic process |
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Gene Properties |
Locus tag: |
PA1276 |
Strand: |
+ |
Entrez Gene ID: |
881414 |
Accession: |
NP_249967.1 |
GI: |
15596473 |
Sequence start: |
1387254 |
Sequence End: |
1388249 |
Sequence Length: |
995 |
Gene Sequence: |
>PA1276
ATGCTTGAACACGGAGGACGGTTGCGCGAGGCGGCGCGCCGTTACGACATTCCGCTGGCGGACTGGCTGGACCTGTCCACCGGCATCGCGCCCTGGCCGTTTTCGCTGCCGGCGATCCCCGAGCAGGCCTGGACCCGCCTGCCGGAGAGCGACGACGGCCTGGAAGCCGCCGCCTGCCTCTACTACGGCGCCGAACGGGTATTGCCGCTGGCTGGCAGCCAGGCGGCGATCCAGGCCCTGCCGAGGATGCGGCGGGGCGGGCGGGTCGGCGTCCTGTCGCCGTGCTACGCCGAGCACGCCCACGCCTGGCGCCAGGCCGGGCACCTGGTGCGGGAGATCGGCGAGGCCGAGGTCGAGCCCTATCTCGACAGCCTCGACGTGCTGCTGGTGGTCAACCCGAACAACCCCACCGGGCGGGTCTTCGAGCCCGCCGAGCTACTGGCCTGGCATGCCCGCCTGCAACGTCGCGGCGGCTGGCTGCTGGTCGACGAGGCGTTCATGGACTGCACCCCGCAGTCGAGCCTGGCGGCCTGCAGCAACCGGCCCGGATTGATCGTGCTGCGCTCGTTCGGCAAGTTCTTCGGCCTGGCCGGCGCGCGGCTCGGCTTCGCCCTCGGCGAACGGCCGCTGTTGCAGGCGCTGGCCGAGCAGCTCGGTCCGTGGACGGTCAATGGCCCGGTGCGCCATGTGGCCCAGAGTGCCTTGCGCGACCGCCAGCAACAGCGCCAGCAGCGCGAGCGCCTGCTGGCCGCCAGCCAGCGCCTGGAGGAACTGCTGCGCCGCCACGGCTGGCCGCCGGCGGGCGGCAGCGCGCTGTTCCAGCGCCTGGTCGATCCACGCTGCGCGGCGTTGCACGACTACCTGGCGCGGCGCGGCATCCTCACCCGCCAATTCGAGCAGCCGGCCAGCCTGCGCCTCGGCCTGCCCGCCGACGAGGCCGCCTGGGCCCGGCTGGATGCCGCGCTGCTCGGCTTCAAGGAGCCTGCTCATGAGTGA |
Protein Properties |
Protein Residues: |
331 |
Protein Molecular Weight: |
36.7 kDa |
Protein Theoretical pI: |
7.95 |
Hydropathicity (GRAVY score): |
-0.224 |
Charge at pH 7 (predicted): |
3.02 |
Protein Sequence: |
>PA1276
MLEHGGRLREAARRYDIPLADWLDLSTGIAPWPFSLPAIPEQAWTRLPESDDGLEAAACLYYGAERVLPLAGSQAAIQALPRMRRGGRVGVLSPCYAEHAHAWRQAGHLVREIGEAEVEPYLDSLDVLLVVNPNNPTGRVFEPAELLAWHARLQRRGGWLLVDEAFMDCTPQSSLAACSNRPGLIVLRSFGKFFGLAGARLGFALGERPLLQALAEQLGPWTVNGPVRHVAQSALRDRQQQRQQRERLLAASQRLEELLRRHGWPPAGGSALFQRLVDPRCAALHDYLARRGILTRQFEQPASLRLGLPADEAAWARLDAALLGFKEPAHE |
References |
External Links: |
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General Reference: |
PaperBLAST - Find papers about PA1276 and its homologs
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