Malate synthase G (PA0482)

Identification
Name: Malate synthase G
Synonyms:
  • MSG
Gene Name: glcB
Enzyme Class:
Biological Properties
General Function: Involved in catalytic activity
Specific Function: Accounts for almost the entire malate-synthesizing activity in cells metabolizing glyoxylate
Cellular Location: Cytoplasm
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb+Thumb ↔ Thumb+Thumb+Thumb
Acetyl-CoA + Glyoxylic acid + Water ↔ Coenzyme A + Hydrogen ion + L-Malic acid
ReactionCard
Thumb+Thumb ↔ Thumb+Thumb+Thumb
L-Malic acid + Coenzyme A ↔ Acetyl-CoA + Water + Glyoxylic acid
ReactionCard
SMPDB Reactions:
Thumb+Thumb+Thumb → Thumb+Thumb+L-Malic acid+Thumb
Glyoxylic acid + Water + Acetyl-CoA → Coenzyme A + Hydrogen ion + L-Malic acid + L-Malic acid
ReactionCard
PseudoCyc/BioCyc Reactions:
Thumb+Thumb+Thumb ↔ Thumb+Thumb+Thumb
Acetyl-CoA + Glyoxylic acid + Water ↔ Coenzyme A + Hydrogen ion + L-Malic acid
ReactionCard
Thumb+Thumb+Thumb → Thumb+Thumb+Thumb
Acetyl-CoA + Water + Glyoxylic acid → Hydrogen ion + L-Malic acid + Coenzyme A
ReactionCard
Complex Reactions: Not Available
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000298Acetyl-CoAMetaboCard
PAMDB000381Coenzyme AMetaboCard
PAMDB000043Glyoxylic acidMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB000058L-Malic acidMetaboCard
PAMDB000142WaterMetaboCard
GO Classification:
Function
catalytic activity
malate synthase activity
transferase activity
transferase activity, transferring acyl groups
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer
Process
carbohydrate metabolic process
cellular carbohydrate metabolic process
glyoxylate cycle
metabolic process
primary metabolic process
Gene Properties
Locus tag: PA0482
Strand: -
Entrez Gene ID: 879477
Accession: NP_249173.1
GI: 15595679
Sequence start: 542170
Sequence End: 544347
Sequence Length: 2177
Gene Sequence: 
>PA0482
ATGACTGAACGCGTTCAAGTCGGTGGCCTGCAGGTCGCCAAAGTCCTGTTCGACTTCGTGAACAACGAAGCCATCCCCGGAACCGGCGTCTCTGCCGACACGTTCTGGACCGGTGCGGAGGCCGTGATCAACGACCTGGCGCCGAAGAATAAAGCCCTGCTCGCCAAGCGCGACGAACTCCAGGCCAAGATCGACGGCTGGCACCAGGCTCGCGCCGGCCAGGCCCACGACGCAGTTGCCTACAAGGCCTTCCTCGAGGAAATCGGCTACCTGCTGCCCGAGGCGGAAGACTTCCAGGCCGGCACCCAGAACGTCGACGACGAGATCGCCCGCATGGCCGGCCCGCAGCTGGTGGTGCCGGTGATGAATGCGCGCTTCGCCCTCAACGCCTCCAACGCCCGCTGGGGCTCGCTGTACGACGCACTCTACGGCACCGACGTGATCAGCGAAGAAGGCGGCGCCGAGAAAGGCAAGGGCTACAACAAGGTTCGCGGCGACAAGGTCATCGCCTTCGCTCGCGCCTTCCTCGACGAGGCCGCGCCGCTGGAGTCCGGCTCCCATGTCGACGCCACTTCCTACAGCGTGAAGAACGGCGCGCTGGTCGTCGCGCTGAAGAACGGCAGCGAAACCGGCCTGAAGAATGCTGGCCAGTTCCTTGCCTTCCAGGGCGACGCCGCCAAGCCGCAAGCGGTACTGCTCAAGCACAACGGCCTGCACTTCGAAATCCAGATCGACCCGAGCAGCCCGGTCGGCCAGACCGATGCCGCAGGCGTGAAGGACGTGCTGATGGAAGCCGCCCTCACCACCATCATGGACTGCGAGGACTCGGTCGCCGCGGTCGACGCCGACGACAAGGTAGTGATCTACCGCAACTGGCTGGGCCTGATGAAAGGCGACCTGGCCGAGGAAGTCAGCAAGGGCGGCAGCACCTTCACCCGCACCATGAACCCGGACCGCGTCTACACCAGGGCCGACGGTTCCGAACTGACCCTGCACGGCCGCTCGCTGCTGTTCGTGCGCAACGTCGGCCACCTGATGACCAACGATGCGATCCTCGACAAGGACGGCAACGAAGTGCCGGAAGGCATCCAGGACGGTCTGTTCACCAGCCTGATCGCCATTCATGACCTGAACGGCAACACCAGCCGCAAGAACAGCCGCACCGGCAGCGTGTATATCGTCAAGCCGAAGATGCACGGTCCGGAAGAAGCCGCCTTCACCAACGAGCTGTTCGGCCGCGTCGAGGACGTCCTCGGCCTGCCGCGCAACACCCTGAAGGTCGGCATCATGGACGAGGAGCGCCGCACCACCGTGAACCTGAAGGCCTGCATCAAGGCGGCCAAGGATCGCGTGGTGTTCATCAACACCGGCTTCCTCGACCGCACCGGCGACGAGATCCACACCTCCATGGAAGCCGGCGCCGTGGTGCGCAAGGGCGCCATGAAGTCGGAGAAGTGGATCGGCGCCTACGAGAACAACAACGTCGACGTCGGCCTGGCCACCGGCCTGCAAGGCAAGGCGCAGATCGGCAAGGGCATGTGGGCCATGCCCGACCTGATGGCCGCCATGCTCGAGCAGAAGATCGGCCATCCGCTGGCCGGCGCCAACACCGCCTGGGTCCCGTCGCCGACCGCCGCGACCCTGCACGCCCTGCATTACCACAAGGTCGACGTGTTCGCCCGCCAGGCCGAGCTGGCCAAGCGCACCCCGGCCTCGGTGGACGACATCCTGACCATTCCGCTGGCGCCGAACACCAACTGGACCGCGGAAGAGATCAAGAACGAGGTGGACAACAACGCCCAGGGCATCCTCGGCTATGTCGTCCGCTGGATCGACCAGGGCGTCGGCTGCTCCAAGGTGCCGGACATCAACGACGTCGGTCTGATGGAAGACCGCGCCACCCTGCGCATCTCCAGCCAACTGCTGGCCAACTGGCTGCGTCACGGCGTGATCAGCCAGGAGCAGGTGGTCGAGAGCCTCAAGCGCATGGCCGTGGTGGTCGACCGGCAGAACGCCAGCGACCCGTCCTACCGGCCGATGGCGCCGAACTTCGACGACAACGTCGCGTTCCAGGCCGCCCTGGAGCTGGTGGTGGAAGGCACCCGGCAGCCGAACGGCTATACCGAGCCGGTCCTGCATCGCCGCCGCCGTGAGTTCAAGGCGAAGAACGGGCTGTAG
Protein Properties
Protein Residues: 725
Protein Molecular Weight: 78.7 kDa
Protein Theoretical pI: 5.45
Hydropathicity (GRAVY score): -0.251
Charge at pH 7 (predicted): -14.19
Protein Sequence: 
>PA0482
MTERVQVGGLQVAKVLFDFVNNEAIPGTGVSADTFWTGAEAVINDLAPKNKALLAKRDELQAKIDGWHQARAGQAHDAVAYKAFLEEIGYLLPEAEDFQAGTQNVDDEIARMAGPQLVVPVMNARFALNASNARWGSLYDALYGTDVISEEGGAEKGKGYNKVRGDKVIAFARAFLDEAAPLESGSHVDATSYSVKNGALVVALKNGSETGLKNAGQFLAFQGDAAKPQAVLLKHNGLHFEIQIDPSSPVGQTDAAGVKDVLMEAALTTIMDCEDSVAAVDADDKVVIYRNWLGLMKGDLAEEVSKGGSTFTRTMNPDRVYTRADGSELTLHGRSLLFVRNVGHLMTNDAILDKDGNEVPEGIQDGLFTSLIAIHDLNGNTSRKNSRTGSVYIVKPKMHGPEEAAFTNELFGRVEDVLGLPRNTLKVGIMDEERRTTVNLKACIKAAKDRVVFINTGFLDRTGDEIHTSMEAGAVVRKGAMKSEKWIGAYENNNVDVGLATGLQGKAQIGKGMWAMPDLMAAMLEQKIGHPLAGANTAWVPSPTAATLHALHYHKVDVFARQAELAKRTPASVDDILTIPLAPNTNWTAEEIKNEVDNNAQGILGYVVRWIDQGVGCSKVPDINDVGLMEDRATLRISSQLLANWLRHGVISQEQVVESLKRMAVVVDRQNASDPSYRPMAPNFDDNVAFQAALELVVEGTRQPNGYTEPVLHRRRREFKAKNGL
References
External Links:
Resource Link
Genome ID: PA0482
Entrez Gene ID: 879477
NCBI Protein ID: 15595679
General Reference: PaperBLAST - Find papers about PA0482 and its homologs