Search Results for compounds

Description: Tetradecenoate (n-c14:1) belongs to the class of Unsaturated Fatty Acids. These are fatty acids whose chain contains at least one CC double bond.

Description: trans-Octadec-2-enoyl-CoA is an intermediate in Biosynthesis of unsaturated fatty acids. trans-Octadec-2-enoyl-CoA is produced from 3-Hydroxyoctadecanoyl-CoA and then converted to Stearoyl-CoA via enzymatic reaction.

Description: The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides

Description: Undecaprenyl phosphate-4-amino-4-formyl-L-arabinose is an intermediate in LPS (lipopolysaccharide) biosynthesis. It is a substrate for the enzyme Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase (arnC). This enzyme catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. The reaction is: UDP-4-deoxy-4-formamido-beta-L-arabinose + di-trans,octa-cis-undecaprenyl phosphate = UDP + 4-deoxy-4-formamido-alpha-L-arabinose di-trans,octa-cis-undecaprenyl phosphate.

Description: Uridine 5''-diphospho-{beta}-4-deoxy-4-amino-L-arabinose is a member of the chemical class known as Pyrimidine Nucleotide Sugars. These are pyrimidine nucleotides bound to a saccharide derivative through the terminal phosphate group.

Description: Uridine 5''-diphospho-{beta}-4-deoxy-4-formamido-L-arabinose is a member of the chemical class known as Pyrimidine Ribonucleoside Diphosphates. These are pyrimidine ribobucleotides with diphosphate group linked to the ribose moiety.

Description: Ferric enterobactin is a member of the chemical class known as Catechols. These are compounds containing a 1,2-benzenediol moeity. Ferric enterobactin is a catecholate siderophore that binds with high affinity (Kd approximately 10-10 M) to the Pseudomonas aeruginosa outer membrane protein FepA. (PMID 10998164) The Pseudomonas aeruginosa FepA protein is an energy- and TonB-dependent, ligand-binding porin that functions as a receptor for the siderophore ferric enterobactin and colicins B and D. (PMID 9268330) The periplasmic protein FepB of Pseudomonas aeruginosa is a component of the ferric enterobactin transport system. (PMID 10986237) The ferric enterobactin receptor, FepA, is a TonB-dependent gated porin that transports the siderophore ferric enterobactin across the outer membrane of gram-negative bacteria. (PMID 7947735) In Pseudomonas aeruginosa, the outer membrane protein FepA is a receptor for the siderophore complex ferric enterobactin and for colicins B and D. (PMID 2201687) FepA is an Pseudomonas aeruginosa outer membrane receptor protein for the siderophore ferric enterobactin. (PMID 7504275) FepA is the Pseudomonas aeruginosa outer membrane receptor for ferric enterobactin, colicin D and colicin B. (PMID 11532122)

Description: L-idonate is a member of the chemical class known as Sugar Acids and Derivatives. These are compounds containing a saccharide unit which bears a carboxylic acid group. L-idonate is a metabolite in D-gluconate catabolism. The catabolic sequence for l-idonate is as follows: l-idonate is transported by the l-idonate transporter, IdnT; l-idonate is oxidized to 5-keto-gluconate (5KG) by l-idonate 5-dehydrogenase, IdnD; 5KG is reduced to d-gluconate by 5-keto-D-gluconate 5-reductase, IdnO; and d-gluconate is phosphorylated by a thermosensitive gluconate kinase, IdnK, to make 6-phosphogluconate (6PG), which is further catabolized via the Entner-Doudoroff pathway. Thus, IdnD and IdnO allow for the redox-coupled interconversion of l-idonate to d-gluconate via 5KG. The l-idonate catabolic pathway overlaps d-gluconate catabolism through the common intermediates d-gluconate and 6PG.

Description: Phosphates are important in biochemistry and biogeochemistry or ecology. In ecology, because of its important role in biological systems, phosphate is a highly sought after resource. Once used, it is often a limiting nutrient in environments, and its availability may govern the rate of growth of organisms. In biological systems, phosphorus is found as a free phosphate ion in solution and is called inorganic phosphate, to distinguish it from phosphates bound in various phosphate esters. Inorganic phosphate is generally denoted Pi, and at physiological (neutral) pH primarily consists of a mixture of HPO4(2-) and H2PO4(-) ions. Phosphates in cells are most commonly found in the form of adenosine phosphates (AMP, ADP and ATP) and in DNA and RNA and can be released by the hydrolysis of ATP or ADP. In addition, the addition and removal of phosphate from proteins in all cells (by kinases and phosphatases) is a pivotal strategy in the regulation of metabolic processes. (Wikipedia) Because the addition and removal of phosphates to and from biochemical compounds is so common, inorganic phosphate (Pi) is involved in a huge number of reactions in Pseudomonas aeruginosa. Also, many Pseudomonas aeruginosa enzymes are activated or inhibited by phosphate. (EcoCyc) Some processes that phosphates (Pi) are involved with in Pseudomonas aeruginosa are oxidative phosphorylation, where a phosphate is added to ADP to make ATP, and biosynthesis of peptidoglycan, a component of bacterial cell walls. (KEGG)

Description: Deoxycholic acid is a bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to solubilize fats for intestinal absorption, is reabsorbed itself, and is used as a choleretic and detergent. Bile acids are steroid acids found predominantly in bile of mammals. The distinction between different bile acids is minute, depends only on presence or absence of hydroxyl groups on positions 3, 7, and 12.