GDP-mannose 4,6-dehydratase (PA5453)

Identification
Name: GDP-mannose 4,6-dehydratase
Synonyms:
  • GDP-D-mannose dehydratase
Gene Name: gmd
Enzyme Class:
Biological Properties
General Function: Involved in catalytic activity
Specific Function: GDP-mannose = GDP-4-dehydro-6-deoxy-D-mannose + H(2)O
Cellular Location: Not Available
KEGG Pathways:
KEGG Reactions:
Thumb ↔ Thumb+Thumb
Guanosine diphosphate mannose ↔ GDP-4-Dehydro-6-deoxy-D-mannose + Water
ReactionCard
SMPDB Reactions:
Thumb → Thumb+Thumb
Guanosine diphosphate mannose → Water + GDP-4-Dehydro-6-deoxy-D-mannose
ReactionCard
Thumb → Thumb+Thumb
Guanosine diphosphate mannose → Water + GDP-4-dehydro-6-deoxy-α-D-mannose
ReactionCard
Thumb → GDP-4-Dehydro-6-L-deoxygalactose+Thumb
Guanosine diphosphate mannose → GDP-4-Dehydro-6-L-deoxygalactose + GDP-4-Dehydro-6-L-deoxygalactose
ReactionCard
PseudoCyc/BioCyc Reactions:
Thumb ↔ Thumb+Thumb
Guanosine diphosphate mannose ↔ GDP-4-Dehydro-6-deoxy-D-mannose + Water
ReactionCard
Complex Reactions:
Thumb → Thumb+Thumb
Guanosine diphosphate mannose → GDP-4-Dehydro-6-deoxy-D-mannose + Water
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000347GDP-4-Dehydro-6-deoxy-D-mannoseMetaboCard
PAMDB006359GDP-4-dehydro-6-deoxy-α-D-mannoseMetaboCard
PAMDB000366GDP-4-Dehydro-6-L-deoxygalactoseMetaboCard
PAMDB000279Guanosine diphosphate mannoseMetaboCard
PAMDB000142WaterMetaboCard
GO Classification:
Component
cell part
intracellular
Function
binding
carbon-oxygen lyase activity
catalytic activity
coenzyme binding
cofactor binding
GDP-mannose 4,6-dehydratase activity
hydro-lyase activity
lyase activity
Process
alcohol metabolic process
cellular metabolic process
GDP-mannose metabolic process
hexose metabolic process
mannose metabolic process
metabolic process
monosaccharide metabolic process
small molecule metabolic process
Gene Properties
Locus tag: PA5453
Strand: -
Entrez Gene ID: 883089
Accession: NP_254140.1
GI: 15600646
Sequence start: 6143109
Sequence End: 6144080
Sequence Length: 971
Gene Sequence: 
>PA5453
ATGACAAGAAGTGCACTGGTAACTGGGATCACCGGTCAGGACGGAGCGTACCTGGCCAAGCTGCTGCTGGAGAAGGGCTACCGGGTCCACGGCCTGGTGGCGCGGCGCAGCAGCGACACGCGCTGGCGCCTGCGCGAACTGGGGATCGAAGGCGATATCCAGTACGAGGACGGCGACATGGCCGATGCCTGTTCGGTGCAGCGCGCGGTGATCAAGGCGCAGCCGCAGGAGGTCTACAACCTGGCGGCACAGAGCTTCGTCGGGGCCTCCTGGAACCAGCCGGTGACCACCGGCGTCGTCGACGGCCTGGGCGTGACCCACCTGCTCGAGGCGATCCGCCAGTTCAGCCCGGAAACGCGCTTCTACCAGGCTTCCACCAGCGAGATGTTCGGCCTGATCCAGGCCGAGCGCCAGGACGAGAACACGCCGTTCTACCCGCGCAGCCCCTACGGCGTGGCCAAGCTCTATGGCCACTGGATCACCGTCAACTATCGCGAGAGCTTCGGCCTGCACGCCTCCAGCGGCATCCTGTTCAACCACGAATCGCCGCTGCGCGGCATCGAGTTCGTCACGCGCAAGGTTACCGACGCGGTGGCCCGCATCAAGCTCGGCAAGCAGCAGGAATTGCGCCTGGGCAACGTCGACGCCAAGCGCGACTGGGGCTTTGCCGGGGACTACGTCGAAGCCATGTGGCTGATGTTGCAGCAGGACAAGGCCGACGACTACGTGGTGGCCACCGGTGTCACTACCACCGTGCGCGACATGTGCCAGATCGCTTTCGAGCATGTGGGCCTGGACTACCGCGACTTCCTCAAGATCGACCCGGCGTTCTTCCGGCCCGCCGAGGTCGACGTGCTGCTGGGTAATCCGGCCAAGGCCCAGCGTGTGCTCGGCTGGAAGCCCAGGACCAGCCTGGACGAGCTGATCCGGATGATGGTCGAGGCGGACCTGCGACGCGTTTCCCGGGAGTAA
Protein Properties
Protein Residues: 323
Protein Molecular Weight: 36.4 kDa
Protein Theoretical pI: 6.53
Hydropathicity (GRAVY score): -0.291
Charge at pH 7 (predicted): -1.61
Protein Sequence: 
>PA5453
MTRSALVTGITGQDGAYLAKLLLEKGYRVHGLVARRSSDTRWRLRELGIEGDIQYEDGDMADACSVQRAVIKAQPQEVYNLAAQSFVGASWNQPVTTGVVDGLGVTHLLEAIRQFSPETRFYQASTSEMFGLIQAERQDENTPFYPRSPYGVAKLYGHWITVNYRESFGLHASSGILFNHESPLRGIEFVTRKVTDAVARIKLGKQQELRLGNVDAKRDWGFAGDYVEAMWLMLQQDKADDYVVATGVTTTVRDMCQIAFEHVGLDYRDFLKIDPAFFRPAEVDVLLGNPAKAQRVLGWKPRTSLDELIRMMVEADLRRVSRE
References
External Links:
Resource Link
Genome ID: PA5453
Entrez Gene ID: 883089
NCBI Protein ID: 15600646
General Reference: PaperBLAST - Find papers about PA5453 and its homologs