DNA helicase II (PA5443)
Identification | ||||||||||||||||||||||||||||||||||
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Name: | DNA helicase II | |||||||||||||||||||||||||||||||||
Synonyms: | Not Available | |||||||||||||||||||||||||||||||||
Gene Name: | uvrD | |||||||||||||||||||||||||||||||||
Enzyme Class: | ||||||||||||||||||||||||||||||||||
Biological Properties | ||||||||||||||||||||||||||||||||||
General Function: | Replication, recombination and repair | |||||||||||||||||||||||||||||||||
Specific Function: | Has both ATPase and helicase activities. Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present. Involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair | |||||||||||||||||||||||||||||||||
Cellular Location: | Cytoplasmic | |||||||||||||||||||||||||||||||||
KEGG Pathways: |
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KEGG Reactions: | Not Available | |||||||||||||||||||||||||||||||||
SMPDB Reactions: | Not Available | |||||||||||||||||||||||||||||||||
PseudoCyc/BioCyc Reactions: |
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Complex Reactions: |
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Transports: | Not Available | |||||||||||||||||||||||||||||||||
Metabolites: |
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GO Classification: |
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Gene Properties | ||||||||||||||||||||||||||||||||||
Locus tag: | PA5443 | |||||||||||||||||||||||||||||||||
Strand: | + | |||||||||||||||||||||||||||||||||
Entrez Gene ID: | 877766 | |||||||||||||||||||||||||||||||||
Accession: | NP_254130.1 | |||||||||||||||||||||||||||||||||
GI: | 15600636 | |||||||||||||||||||||||||||||||||
Sequence start: | 6131088 | |||||||||||||||||||||||||||||||||
Sequence End: | 6133274 | |||||||||||||||||||||||||||||||||
Sequence Length: | 2186 | |||||||||||||||||||||||||||||||||
Gene Sequence: |
>PA5443 ATGAACGACGACCTCTCCCTCCTGCTGAACTCCCTCAACGACCCGCAGCGCCAGGCCGTGGCCGCGCCGCTGGGCCGCCAACTGGTCCTCGCCGGCGCCGGCTCGGGCAAGACCCGCGTGCTGGTGCACCGGATCGCCTGGCTGATCCAGGTCGAGCACGCCTCGCCCTACAGCATCCTGTCGGTGACCTTCACCAACAAGGCGGCGGCGGAGATGCGCCACCGCATCGAGCAGTTGCTCGGGATCAATCCGGCGGGCATGTGGGTCGGCACCTTCCACGGCCTCGCCCATCGCCTGCTGCGCGCGCACTGGCGCGAGGCCGGGCTGAGCGAGAACTTCCAGATCCTCGACAGCGACGACCAGCAACGCCTGGTCAAGCGGGTGATCCGCGAACTCGGCCTCGACGAGCAGCGCTGGCCGGCGCGCCAGGCCCAGTGGTTCATCAACGGGCAGAAGGACGAGGGCCTGCGGCCGCAACACATCCAGCCCGGCGGCGACCTGTTCCTCGCCACCATGCTGAAGATCTACGAAGCCTACGAGGCGGCCTGCGCCCGCGCCGGGGTGATCGACTTCTCCGAGCTGCTGCTGCGCGCCCTGGACCTCTGGCGCGACCATCCCGGCGTGCTCGAGCACTACCAGCGGCGCTTCCGCCATATCCTGGTGGACGAGTTCCAGGACACCAACGCCGTGCAATACGCCTGGCTGCGGATTCTCGCCAAGGGCGGCGACAGCCTGATGGTGGTCGGCGACGACGACCAGTCGATCTACGGCTGGCGTGGCGCACGGATCGAGAACATCCAGCAGTTCAGCGACGACTTCGCCGATGCCGAGGTGATCCGCCTGGAGCAGAACTACCGTTCCACCGCGTCGATCCTCAAGGCCGCCAACGCCCTGATCGCCAACAACCAGGGACGCCTGGGCAAGGAGTTGTGGACCGACGGCGAGGACGGCGAGTCGCTGAGCCTGTACGCCGCGTTCAACGAGCACGACGAGGCGCGCTACGTGGTCGAGTCGATCGAGAGCGCGCTCAAGGGCGGCCTGGCGCGCAGCGAGATCGCCATCCTCTACCGCTCCAACGCCCAGTCGCGGGTGCTGGAGGAAGCCCTGCTGCGGGAGAAGATTCCCTACCGCATCTACGGCGGCCAGCGCTTCTTCGAGCGTGCCGAGATCAAGAACGCCATGGCCTACCTGCGCCTGCTCGACGGCCGCGGCAACGACGCGGCGCTGGAACGGGTGGTCAACGTGCCGGCACGCGGCATCGGCGAGAAGACCGTGGAGAGCATCCGCGAATTCGCCCGCGGCAACGATGTGTCGATGTGGGAGGCGATCCGCCTGATGATCGCCAACAAGGTCCTGCCCGGCCGCGCCGCCAGCGCCCTGACCGGCTTCGTCGAGCTGATCGAGAATCTTTCGGCGAAGGTCATGGACATGCCGCTGCACCTGATGACCCAGACGGTGATCGAGCAGTCCGGACTGATCAGCTACCACAAGGAAGAAAAAGGCGAGAAAGGCCAGGCCCGGGTGGAGAACCTCGAGGAACTGGTCAGCGCCGCCCGCGCCTTCGAGAACAGCGAGGAAGAGGAAGACCTCACCCCGCTGCAGGCCTTCCTCAGCCACGCCTCCCTGGAGGCCGGGGAAACCCAGGCCGACGCCCACGAGGACAGTGTCCAGCTGATGACCCTGCACAGCGCCAAGGGCCTGGAGTTCCCGCTGGTGTTCCTGGTCGGCATGGAGGAAGGGCTGTTCCCGCACAAGATGAGCCTGGAGGAATCCGGCCGCCTGGAAGAGGAACGCCGCCTGGCCTACGTCGGCGTCACCCGCGCCATGCAGCGACTGGTCCTGACCTACGCGGAGACCCGCCGGCTCTACGGTAGCGAGACCTACAACAAGGTTTCGCGCTTCATCCGCGAGATCCCGCCGGCGCTGATCCAGGAAGTGCGCCTGTCCAATACCGTCAGCCGCCCCTACGGCGGCACCTCGCGCAGTGCCGGCGGCAACCTCTTCAGCGGCGCCGGGGTGCCGGAGACGCCCTTCTCCCTCGGCCAGCGGGTGCGCCACGCGCTGTTCGGCGAAGGGACTATCCTCAACTTCGAAGGCGCCGGCGCCCAGGCCCGGGTGCAGGTGAATTTCGAGAGCGAAGGCAGCAAGTGGCTGATGCTCGGCTACGCCAAGCTGGAAGCCCTGTAG | |||||||||||||||||||||||||||||||||
Protein Properties | ||||||||||||||||||||||||||||||||||
Protein Residues: | 728 | |||||||||||||||||||||||||||||||||
Protein Molecular Weight: | 81.5 kDa | |||||||||||||||||||||||||||||||||
Protein Theoretical pI: | 5.67 | |||||||||||||||||||||||||||||||||
Hydropathicity (GRAVY score): | -0.283 | |||||||||||||||||||||||||||||||||
Charge at pH 7 (predicted): | -13.64 | |||||||||||||||||||||||||||||||||
Protein Sequence: |
>PA5443 MNDDLSLLLNSLNDPQRQAVAAPLGRQLVLAGAGSGKTRVLVHRIAWLIQVEHASPYSILSVTFTNKAAAEMRHRIEQLLGINPAGMWVGTFHGLAHRLLRAHWREAGLSENFQILDSDDQQRLVKRVIRELGLDEQRWPARQAQWFINGQKDEGLRPQHIQPGGDLFLATMLKIYEAYEAACARAGVIDFSELLLRALDLWRDHPGVLEHYQRRFRHILVDEFQDTNAVQYAWLRILAKGGDSLMVVGDDDQSIYGWRGARIENIQQFSDDFADAEVIRLEQNYRSTASILKAANALIANNQGRLGKELWTDGEDGESLSLYAAFNEHDEARYVVESIESALKGGLARSEIAILYRSNAQSRVLEEALLREKIPYRIYGGQRFFERAEIKNAMAYLRLLDGRGNDAALERVVNVPARGIGEKTVESIREFARGNDVSMWEAIRLMIANKVLPGRAASALTGFVELIENLSAKVMDMPLHLMTQTVIEQSGLISYHKEEKGEKGQARVENLEELVSAARAFENSEEEEDLTPLQAFLSHASLEAGETQADAHEDSVQLMTLHSAKGLEFPLVFLVGMEEGLFPHKMSLEESGRLEEERRLAYVGVTRAMQRLVLTYAETRRLYGSETYNKVSRFIREIPPALIQEVRLSNTVSRPYGGTSRSAGGNLFSGAGVPETPFSLGQRVRHALFGEGTILNFEGAGAQARVQVNFESEGSKWLMLGYAKLEAL | |||||||||||||||||||||||||||||||||
References | ||||||||||||||||||||||||||||||||||
External Links: |
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General Reference: | PaperBLAST - Find papers about PA5443 and its homologs |