CdhA, Carnitine dehydrogenase (PA5386)

Identification
Name: CdhA, Carnitine dehydrogenase
Synonyms: Not Available
Gene Name: cdhA
Enzyme Class: Not Available
Biological Properties
General Function: oxidation-reduction process, fatty acid metabolic process, carnitine catabolic process
Specific Function: coenzyme binding, NAD+ binding, oxidoreductase activity, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, 3-hydroxyacyl-CoA dehydrogenase activity
Cellular Location: Cytoplasmic
KEGG Pathways:
  • Carnitine Catabolism to Glycine Betaine PWYB-96
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
    Thumb
    L-carnitine + NAD+ → 3-dehydrocarnitine + NADH + H+
    ReactionCard
    Thumb
    acetoacetyl-CoA + NADH = (R)-3-hydroxybutanoyl-CoA + NAD+
    ReactionCard
    PAMDB110396+PAMDB110541 → PAMDB110399+PAMDB110539+PAMDB001633
    (S)-3-hydroxybutanoyl-CoA + NADP+ → acetoacetyl-CoA + NADPH + Hydrogen ion
    ReactionCard
    Complex Reactions: Not Available
    Transports: Not Available
    Metabolites: Not Available
    GO Classification:
    Function
    coenzyme binding
    NAD+ binding
    oxidoreductase activity
    oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    3-hydroxyacyl-CoA dehydrogenase activity
    Process
    oxidation-reduction process
    fatty acid metabolic process
    carnitine catabolic process
    Gene Properties
    Locus tag: PA5386
    Strand: -
    Entrez Gene ID: 881645
    Accession: NP_254073.1
    GI: 15600579
    Sequence start: 6063883
    Sequence End: 6064848
    Sequence Length: 965
    Gene Sequence: 
    >PA5386
ATGTCCTTCGTCACCGAGATCAAGACCTTCGCCGCCCTCGGTAGCGGCGTCATCGGCAGCGGCTGGATCGCCCGCGCCCTGGCCCACGGCCTCGACGTCGTCGCCTGGGATCCGGCGCCGGGCGCCGAAGCGGCGTTGCGCGCGCGCGTCGCCAATGCCTGGCCGGCCTTGCGGAAACAGGGCCTGGCGCCCGGCGCGGCGCAGGAGCGCCTGCGCTTCGTCGCGAGCATCGAGGAATGCGTGGGCGACGCCGATTTCATCCAGGAGAGCGCCCCCGAGCGGCTCGACCTGAAGCTCGACCTGCACGCCAGGATCAGCGCCGCGGCGCGGCCCGACGTGCTGATCGGTTCCTCCACCTCGGGCCTGCTGCCCAGCGAGTTCTACGCCGAGGCGAGCCACCCCGAGCGCTGCCTGGTCGGCCACCCGTTCAACCCGGTCTACCTGCTGCCGCTGGTGGAGGTGGTCGGCGGTGAACGCACCGCTGCCGAGGCCGTGCGGGCGGCGATGCGGGTCTACGAATCGCTGGGCATGCGTCCGCTGCACGTACGCAAGGAAGTGCCCGGCTTCATCGCCGACCGCTTGCTCGAGGCGCTCTGGCGCGAGGCGCTGCACCTGGTCAACGACGGCGTGGCCACGACCGGCGAGATCGACGATGCGATCCGCTTCGGCGCCGGCCTGCGCTGGTCGTTCATGGGCACCTTCCTGACCTACACCCTGGCCGGTGGCAACGCCGGCATGCGCCACTTCATGGCGCAGTTCGGCCCGGCGCTGCAATTGCCCTGGACCTACCTGCCGGCGCCGGAACTCACCGAGGCCCTGATCGACCGGGTGGTGGAGGGCACCGCCGAGCAGCAGGGCGCGCGCAGCATCGCCGAGCTCGAGCGCTACCGCGACGACTGCCTGCTGGCGGTGCTCGGGGCGATCAGGGAAACCAAGGCCCGGCACGGCTTCGCCTTCGCCGAGTGA
    Protein Properties
    Protein Residues: 321
    Protein Molecular Weight: 34.7 kDa
    Protein Theoretical pI: 5.42
    Hydropathicity (GRAVY score): 0.089
    Charge at pH 7 (predicted): -7.16
    Protein Sequence: 
    >PA5386
MSFVTEIKTFAALGSGVIGSGWIARALAHGLDVVAWDPAPGAEAALRARVANAWPALRKQGLAPGAAQERLRFVASIEECVGDADFIQESAPERLDLKLDLHARISAAARPDVLIGSSTSGLLPSEFYAEASHPERCLVGHPFNPVYLLPLVEVVGGERTAAEAVRAAMRVYESLGMRPLHVRKEVPGFIADRLLEALWREALHLVNDGVATTGEIDDAIRFGAGLRWSFMGTFLTYTLAGGNAGMRHFMAQFGPALQLPWTYLPAPELTEALIDRVVEGTAEQQGARSIAELERYRDDCLLAVLGAIRETKARHGFAFAE
    References
    External Links:
    Resource Link
    Genome ID: PA5386
    Entrez Gene ID: 881645
    NCBI Protein ID: 15600579
    General Reference: PaperBLAST - Find papers about PA5386 and its homologs