Identification
Name: ATP-dependent DNA helicase rep
Synonyms: Not Available
Gene Name: rep
Enzyme Class:
Biological Properties
General Function: Replication, recombination and repair
Specific Function: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction
Cellular Location: Cytoplasmic
KEGG Pathways:
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
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    Complex Reactions:
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    Transports: Not Available
    Metabolites:
    PAMDB IDNameView
    PAMDB000148Adenosine triphosphateMetaboCard
    PAMDB000345ADPMetaboCard
    PAMDB001776Inorganic phosphateMetaboCard
    PAMDB000142WaterMetaboCard
    GO Classification:
    Component
    cell part
    cytoplasm
    intracellular part
    Function
    adenyl nucleotide binding
    adenyl ribonucleotide binding
    ATP binding
    ATP-dependent DNA helicase activity
    binding
    catalytic activity
    DNA binding
    DNA helicase activity
    helicase activity
    hydrolase activity
    hydrolase activity, acting on acid anhydrides
    hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    nucleic acid binding
    nucleoside binding
    nucleoside-triphosphatase activity
    purine nucleoside binding
    pyrophosphatase activity
    Process
    cellular macromolecule metabolic process
    cellular process
    DNA conformation change
    DNA duplex unwinding
    DNA geometric change
    DNA metabolic process
    DNA repair
    DNA unwinding involved in replication
    macromolecule metabolic process
    metabolic process
    Gene Properties
    Locus tag: PA5296
    Strand: +
    Entrez Gene ID: 881391
    Accession: NP_253983.1
    GI: 15600489
    Sequence start: 5962716
    Sequence End: 5964725
    Sequence Length: 2009
    Gene Sequence:
    >PA5296
    ATGTCCCGACTCAATCCCCGGCAGCAAGAAGCCGTGAACTACGTCGGCGGTCCCCTGCTGGTCCTGGCTGGCGCCGGCTCCGGCAAGACCAGCGTGATCACCCGCAAGATCGCCTATCTCGTCCAGCAGTGCGGTATCCGCGCCCAGTACATCGTCGCCGTGACCTTCACCAACAAGGCCGCGCGGGAGATGAAGGAGCGCGTCGGCACCCTGCTGCGCGGCGGCGAGGGCAAGGGCCTGACCGTCTCGACCTTCCACAACCTCGGCCTGAACATCATCCGCAAGGAACACGAACGGCTCGGCTACAAGCCCGGTTTCTCGATCTTCGACGAGTCGGACATCAAGGCGCTGCTGACCGACATCATGCAGAAGGAGTATTCCGGGGACGACGGCGTCGACGAGATCAAGAACTACATCGGCGCCTGGAAGAACGACCTGATCCTTCCGGAGGAGGCGCTGGAAAAGGCCCGCAACCCCAAGGAGCAGACCGCCGCGATCGTCTACCTGCATTACCAGCGCACCCTGCGCGCCTACAACGCGGTGGACTTCGACGACCTGATCCTGCAACCGGTGAAGCTGTTCCAGGAACATCCGGACGTCCTCCAGAAGTGGCAGAACAAGGTGCGCTACATGCTGGTGGACGAGTACCAGGACACCAACGCCAGCCAGTACCTGCTGGTCAAGCTGCTGGTGAAGGACCGCGCCCAGTTCACCGTGGTCGGCGACGACGATCAGTCGATCTACGCCTGGCGCGGCGCGCGTCCGGAAAACCTGATGCAGCTGAAGGAAGACTTCCCTTCGCTGAAGGTGGTGATGCTGGAGCAGAACTACCGCTCCACCAGCCGCATCCTCAAGTGCGCGAACGTCCTCATCGCCAACAACCCGCACGTATTCGAGAAGCAGTTGTGGAGCGAGATGGGCCACGGCGATCCGATCCGGGTGATCCGCTGCCGCAACGAGGACGCCGAGGCCGAGCGCATCGCCATGGAGATCCTCACCCTGCACCTGCGCACCGAGCGGCCGTACAGCGAGTTCGCCATCCTCTACCGTGGCAACCACCAGGCCAAGCTGATGGAGCTGAAGCTCCAGCACCACCAGATTCCCTATCGGCTCTCTGGCGGCACCAGCTTCTTCGGGCGCCAGGAAGTGAAGGACCTGATGTCCTACTTCCGCCTGCTGGTGAACCCCGACGACGACAACGCCTTCCTCAGGGTGATCAACGTGCCGCGCCGGGAAATCGGTTCGGCGACCCTGGAGAAGCTCGGCAACTACGCCACCCAGCGCAAGATCTCGATGTACGCCGCCTGCGACGAGATGGGCCTGGCCGAGCACCTCGACAGCCGTTTCCACGAACGCCTGCAACGCTTCAAGCGCTGGATGGACGGTATCCGCCGACAGTGCGCGGAGAACGAGCCGATCGCCGTGCTGCGCAGCATGGTGATGGACATCGACTACGAGAACTGGCTGCGGCAGAACGCCTCCAGCGACAAGGTCGCCGAATTCCGCATGAGCAACGTCTGGTTCCTCATCGAGGCACTGAAGAACACCCTCGAGCGCGACGAGGAAGGCGACATGACCATCGAGCAGGCCATCGCCAAGCTGGTCCTGCGCGACATGCTGGAGCGCCAGCAGGAAGAAGAGGAAGGCGCCGAAGGCGTGCAGATGATGACCCTGCACGCGTCGAAGGGGCTGGAGTTCCCCTACGTGTTCATCATGGGCATGGAGGAAGAGATCCTGCCCCACCGTTCCAGCATCGAGGCCGACACGGTGGAAGAGGAGCGCCGCCTGGCCTACGTCGGCATCACCCGCGCGCGGCAGAACCTGGCGATGACCTTCGCCGCCAAGCGCAAGCAATACGGCGAGATCATCGACTGCTCGCCGAGCCGCTTCCTCGACGAACTGCCCCCCGAAGACCTCGAATGGGAAGGCATGGAAGACGCCCCGCAAGAGGTCAAGGCGGCCAAGGGCAACGCCGCCCTCGCCGACATCCGCGCCATGCTCAAGCGCTGA
    Protein Properties
    Protein Residues: 669
    Protein Molecular Weight: 77 kDa
    Protein Theoretical pI: 5.96
    Hydropathicity (GRAVY score): -0.462
    Charge at pH 7 (predicted): -8.76
    Protein Sequence:
    >PA5296
    MSRLNPRQQEAVNYVGGPLLVLAGAGSGKTSVITRKIAYLVQQCGIRAQYIVAVTFTNKAAREMKERVGTLLRGGEGKGLTVSTFHNLGLNIIRKEHERLGYKPGFSIFDESDIKALLTDIMQKEYSGDDGVDEIKNYIGAWKNDLILPEEALEKARNPKEQTAAIVYLHYQRTLRAYNAVDFDDLILQPVKLFQEHPDVLQKWQNKVRYMLVDEYQDTNASQYLLVKLLVKDRAQFTVVGDDDQSIYAWRGARPENLMQLKEDFPSLKVVMLEQNYRSTSRILKCANVLIANNPHVFEKQLWSEMGHGDPIRVIRCRNEDAEAERIAMEILTLHLRTERPYSEFAILYRGNHQAKLMELKLQHHQIPYRLSGGTSFFGRQEVKDLMSYFRLLVNPDDDNAFLRVINVPRREIGSATLEKLGNYATQRKISMYAACDEMGLAEHLDSRFHERLQRFKRWMDGIRRQCAENEPIAVLRSMVMDIDYENWLRQNASSDKVAEFRMSNVWFLIEALKNTLERDEEGDMTIEQAIAKLVLRDMLERQQEEEEGAEGVQMMTLHASKGLEFPYVFIMGMEEEILPHRSSIEADTVEEERRLAYVGITRARQNLAMTFAAKRKQYGEIIDCSPSRFLDELPPEDLEWEGMEDAPQEVKAAKGNAALADIRAMLKR
    References
    External Links:
    Resource Link
    Genome ID: PA5296
    Entrez Gene ID: 881391
    NCBI Protein ID: 15600489
    General Reference: PaperBLAST - Find papers about PA5296 and its homologs