| Identification |
| Name: |
L-seryl-tRNA(Sec) selenium transferase |
| Synonyms: |
- Selenocysteine synthase
- Sec synthase
- Selenocysteinyl-tRNA(Sec) synthase
|
| Gene Name: |
selA |
| Enzyme Class: |
|
| Biological Properties |
| General Function: |
Involved in catalytic activity |
| Specific Function: |
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. Requires selenophosphate as the selenium-donor molecule |
| Cellular Location: |
Cytoplasm |
| KEGG Pathways: |
|
| KEGG Reactions: |
|
L-Seryl-tRNA(Sec) | + |  | + | L-Seryl-tRNA(Sec) | ↔ | L-Selenocysteinyl-tRNA(Sec) | + |  | + | L-Selenocysteinyl-tRNA(Sec) |
| |
|
| SMPDB Reactions: |
Not Available |
| PseudoCyc/BioCyc Reactions: |
|
| Complex Reactions: |
|
| → |  | + | | + | L-Selenocysteinyl-tRNA(Sec) |
| | |
L-seryl-tRNA(Sec) | + | | → | L-selenocysteinyl-tRNA(Sec) | + |  |
| |
|
| Transports: |
Not Available |
| Metabolites: |
|
| GO Classification: |
| Component |
|---|
| cell part | | cytoplasm | | intracellular part | | Function |
|---|
| catalytic activity | | L-seryl-tRNASec selenium transferase activity | | selenotransferase activity | | transferase activity | | transferase activity, transferring selenium-containing groups | | Process |
|---|
| biosynthetic process | | cellular macromolecule biosynthetic process | | macromolecule biosynthetic process | | metabolic process | | selenocysteine incorporation | | translational elongation | | translational readthrough |
|
| Gene Properties |
| Locus tag: |
PA4808 |
| Strand: |
- |
| Entrez Gene ID: |
880198 |
| Accession: |
NP_253496.1 |
| GI: |
15600002 |
| Sequence start: |
5394445 |
| Sequence End: |
5395851 |
| Sequence Length: |
1406 |
| Gene Sequence: |
>PA4808
ATGAGTTCCGTTCGCTTGCCTTCGGTCGACCGCCTGCTGCGCAGCGCGGCGGCCGCTCCCCTGCACCAGCGCTATGGCCGCGAGGCGTTGCTGGCGACCCTCCGCGACCTGCTCGACGAACTGCGCGAGCCGGCCCGACACGGTGCCCTCGCCGAGATCGAACTGAGCGAGGCGGTGCTCGCCGGGCGCGCCGGCGAACGCCTCGCCGCGCAGCATGCCAGCCGCGTGCGGCGGGTGTTCAACCTGACCGGCACGGTGTTGCATACCAACCTCGGCCGCGCCCTGCTGCCGGACGAAGCCATCGAGGCGATCACCCTGGCCGCGCGCTACCCGCTGAACCTGGAGTTCGACCTGGCCAGCGGCAAGCGCGGCGACCGCGACGACCTGATCGCCGGGCTGATCCGCGAACTCACCGGCGCCGAGGCGGTCACCGTGGTCAACAACAACGCGGCGGCGGTGCTGCTGGCGCTGAACAGCCTGGGGGCGCGCAAGGAAGGGATCATCTCGCGCGGCGAGCTGATCGAGATCGGCGGCGCCTTCCGCATTCCCGACATCATGGCCCGCGCCGGCGTGCGCTTGCACGAGGTGGGCACCACCAACCGCACCCACGCCAAGGACTACGAAGCCGCCATCGGCCCGCGCAGCGGCCTGCTGATGCGCGTGCACACCAGCAACTACAGCGTCCAGGGCTTCACCGCCAGCGTGCCCACCGCGCAACTGGCGGCCATCGCCCATGGCCACGGCCTGCCGCTGCTGGAAGACCTCGGCAGCGGCACCCTGGTGGACCTGACCCGCTGGGGCTTGCCCAAGGAACCGACGGTGCAGGAAGCCCTGGCCGACGGCGCCGACATCGTTACCTTCAGCGGCGACAAATTGCTCGGCGGGCCCCAGGCCGGGCTGATCCTCGGCAACCGCGAACTGATCGGGCGGATCAAGAAGAACCCGCTCAAGCGCGCTCTGCGCGTCGACAAGCTGACCCTCGCCGCCCTCGAGGCGGTGCTCGGCCTGTACCGCGATCCGGACCGCCTCGCCGAACGCCTGACCACCCTGCGCCTGCTCAGCCGCCCGGCGGCGGAGATCCGCGCCCAGGCCGAGCGTCTGGCGCCGGCGCTGGGCGAGGCGCTCGGCGAGGGCTGGGAGGTCGCTGTGGTCGACGCCCTGGGCATGATCGGCAGCGGCGCGCAGCCGGTGGCGCGGCTGGCCAGCGCCGCGCTGTGCCTGCGTCCGCGGCAGCCCAGGCGCCTGCGCGGACGCGCCCTGCGCAACCTCGAGGAAGCCCTGCGCGGGCTGCCGCTGCCGGTGATCGGTCGGCTCGACGACGACGCCCTCTGGCTCGATCTGCGCCAGCTCGACGACGAGCCGGCGTTCCTCGCCCAGTTGCCGCGACTGCGGAGCGAGCTGTCGTGA |
| Protein Properties |
| Protein Residues: |
468 |
| Protein Molecular Weight: |
50.3 kDa |
| Protein Theoretical pI: |
9.41 |
| Hydropathicity (GRAVY score): |
-0.022 |
| Charge at pH 7 (predicted): |
5.16 |
| Protein Sequence: |
>PA4808
MSSVRLPSVDRLLRSAAAAPLHQRYGREALLATLRDLLDELREPARHGALAEIELSEAVLAGRAGERLAAQHASRVRRVFNLTGTVLHTNLGRALLPDEAIEAITLAARYPLNLEFDLASGKRGDRDDLIAGLIRELTGAEAVTVVNNNAAAVLLALNSLGARKEGIISRGELIEIGGAFRIPDIMARAGVRLHEVGTTNRTHAKDYEAAIGPRSGLLMRVHTSNYSVQGFTASVPTAQLAAIAHGHGLPLLEDLGSGTLVDLTRWGLPKEPTVQEALADGADIVTFSGDKLLGGPQAGLILGNRELIGRIKKNPLKRALRVDKLTLAALEAVLGLYRDPDRLAERLTTLRLLSRPAAEIRAQAERLAPALGEALGEGWEVAVVDALGMIGSGAQPVARLASAALCLRPRQPRRLRGRALRNLEEALRGLPLPVIGRLDDDALWLDLRQLDDEPAFLAQLPRLRSELS |
| References |
| External Links: |
|
| General Reference: |
PaperBLAST - Find papers about PA4808 and its homologs
|
