Identification |
Name: |
Nitrate/nitrite sensor protein narX |
Synonyms: |
Not Available |
Gene Name: |
narX |
Enzyme Class: |
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Biological Properties |
General Function: |
Signal transduction mechanisms |
Specific Function: |
Acts as a sensor for nitrate/nitrite and transduces signal of nitrate availability to the narL protein and of both nitrate/nitrite to the narP protein. NarX probably activates narL and narP by phosphorylation in the presence of nitrate. NarX also plays a negative role in controlling narL activity, probably through dephosphorylation in the absence of nitrate |
Cellular Location: |
Cell inner membrane; Multi-pass membrane protein |
KEGG Pathways: |
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KEGG Reactions: |
Not Available |
SMPDB Reactions: |
Not Available |
PseudoCyc/BioCyc Reactions: |
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| + | protein L-histidine | → | | + | protein N-phospho-L-histidine |
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Complex Reactions: |
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| + | protein L-histidine | → | | + | protein N-phospho-L-histidine |
| |
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Transports: |
Not Available |
Metabolites: |
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GO Classification: |
Component |
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cell part | integral to membrane | intrinsic to membrane | membrane | membrane part | Function |
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adenyl nucleotide binding | adenyl ribonucleotide binding | ATP binding | binding | catalytic activity | kinase activity | molecular transducer activity | nucleoside binding | protein binding | protein dimerization activity | protein histidine kinase activity | protein kinase activity | purine nucleoside binding | signal transducer activity | transferase activity | transferase activity, transferring phosphorus-containing groups | two-component sensor activity | Process |
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biological regulation | cellular metabolic process | metabolic process | peptidyl-histidine phosphorylation | phosphate metabolic process | phosphorus metabolic process | phosphorylation | protein amino acid phosphorylation | regulation of biological process | regulation of cellular process | signal transduction | signal transmission | signaling process | two-component signal transduction system (phosphorelay) |
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Gene Properties |
Locus tag: |
PA3878 |
Strand: |
+ |
Entrez Gene ID: |
878321 |
Accession: |
NP_252567.1 |
GI: |
15599073 |
Sequence start: |
4345010 |
Sequence End: |
4346878 |
Sequence Length: |
1868 |
Gene Sequence: |
>PA3878
ATGAACAAGGCGACCGCGCCGGACGCTGACCAGCGGGACAGATTCTTTGGAGGTAGTGACAGGGCCGGAAAGCCGATCCTGCGCCGCTCCCTGGTAGTCCGCTTCGGCTGCTACCTCACCCTGCTGGTATCGCTGGCGCTGATCGGGATGTTCAGCGCCCTGCTCTTCGCCGACTACACGCACCAGGACGCCGCGGTGATCAACCACGCCGGCTCGTTGCGCATGCTCACCTACCGGGTCGCCCTGGAGCCCAGCCTGGAAGGCCGCCAGGCGCTGCTCGGGACCCTCGGCGAACGCCTCGACAGCGGCGACATCCGCCGCCTGCTGCAACGCCAGGACGCCGACGACCCGATCCGCCAGTTGCACCAGGAGCTGCGCGAGGGCCTCGCGCGCCTGGACCCGCGCGCGCTGCCCGGACGCGCCGTGCTGGACGCCTACGTCGGCGACATCGACCGTTTCGTCGGCATCCTCCAGGCCAAGGCCGAGCGCCGCTCGCAACTGCTCAGCACGGTGCAGGGCCTGTGCCTGTTCCTCAGCCTGCTGGTGGTGTTCGTCACCCTCTACGACCTCAGCTATCACGTCATCGGCCCGCTGCGCGAACTCACCAGCACCGCCCGCCGCCTGGGCCGCGGCGAGCTGGACGCGCGGGTCACCTACAGCGGCGAGGACGAACTGGCGCAACTGGGCGAGCGCTTCAACCAGATGGCCGGCGAGCTGAAGAGCATCTACGGCGACCTGGAAGAGCGCGTGGAGGACAAGACCCGCGCCCTCTCGCAGAGCCACCAGCGCCTCGAACTGCTCTACGCCAGCGCCCGCCGGCTGGGCGAGAACCCCTACGACAGCCGCACCCTGCAACCGCTGCTGAACCAGTTGGAGAAAGTGCTCGACGCCGGCCGCGTGACCCTCTGCCTGAACAAGGACGGGGTCGAGCGCGCCTACAGTTCGCTGACCACCACCGAGCGCCCGGCGGACTTCTGCCTGCAGGGCGACTGCGGTAGCTGCCGCGAGCAGGCCAGCGCCTGCGACCAACCCTCGTCCCTGGCCCAGCCATTGCTGATGCAGCCCCTGTCCATCGCCGGCCACCGTTTCGGCGAACTGTTCATCGAAAGCCGCAGCGGCCGCCTGGAGAACTGGCAGCAGCAACTGATCGAGACCTTCTGCGACAACATCGCCCGCACCTTCGCCCTGTCCCTGCAACAGGAACAGGAAAGCCGCCTGGCCCTGTTCGCCGAGCGCGGCACCATCGCCCGCGAACTGCACGATTCGCTGGCACAGTCGCTGTCCTACCTGAAGATCCAGGTCAGCCGCCTGGGCACCCTGCTCAAGCGCGAGGCGCCGGCGGAGAAGATCGAGGACACCCTCGACGAACTGCGCGAAGGCCTCAACGGCGCCTACCGGCAACTGCGCGAACTGCTCACCACCTTCCGCCTCAGCCTCGACGAGCCGAGCCTGGAAGCCGCGCTGGGGAACGCCGTGGCCGAGTTCGGCGAGCGCGGCGAGGTGACGATCGAACTGGACAACCGCCTGCAACACGTGCCGCTGAGCCCCAACGAGGAAATCCACGTCCTGCAGATCGTCCGCGAGGCGCTCTCCAACGTGGTTCGCCATTCGCAGGCGCAACGGGCCTGGGTGCGCCTGAGCAGCCAGGCCGACGGCCAGGTGAGCATCGCCGTCGAGGACGATGGCGTCGGCTTTGATCCGCAGCAGAACCGCAGCGGCCATTATGGGCTTACCATCATGCAGGAGCGCGGCCAGACCCTCGGCAGCCAGTTGCGCTTCGAAGCGCGCGCGCCCCACGGCACGCGAGTGCTCTTCAGCTTCGTGCCGACCGCCCTGCAACCCTCCGCCGCCAAGGAGCCGACCCCATGA |
Protein Properties |
Protein Residues: |
622 |
Protein Molecular Weight: |
69.3 kDa |
Protein Theoretical pI: |
5.71 |
Hydropathicity (GRAVY score): |
-0.309 |
Charge at pH 7 (predicted): |
-9.31 |
Protein Sequence: |
>PA3878
MNKATAPDADQRDRFFGGSDRAGKPILRRSLVVRFGCYLTLLVSLALIGMFSALLFADYTHQDAAVINHAGSLRMLTYRVALEPSLEGRQALLGTLGERLDSGDIRRLLQRQDADDPIRQLHQELREGLARLDPRALPGRAVLDAYVGDIDRFVGILQAKAERRSQLLSTVQGLCLFLSLLVVFVTLYDLSYHVIGPLRELTSTARRLGRGELDARVTYSGEDELAQLGERFNQMAGELKSIYGDLEERVEDKTRALSQSHQRLELLYASARRLGENPYDSRTLQPLLNQLEKVLDAGRVTLCLNKDGVERAYSSLTTTERPADFCLQGDCGSCREQASACDQPSSLAQPLLMQPLSIAGHRFGELFIESRSGRLENWQQQLIETFCDNIARTFALSLQQEQESRLALFAERGTIARELHDSLAQSLSYLKIQVSRLGTLLKREAPAEKIEDTLDELREGLNGAYRQLRELLTTFRLSLDEPSLEAALGNAVAEFGERGEVTIELDNRLQHVPLSPNEEIHVLQIVREALSNVVRHSQAQRAWVRLSSQADGQVSIAVEDDGVGFDPQQNRSGHYGLTIMQERGQTLGSQLRFEARAPHGTRVLFSFVPTALQPSAAKEPTP |
References |
External Links: |
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General Reference: |
PaperBLAST - Find papers about PA3878 and its homologs
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