2,4-dienoyl-CoA reductase [NADPH] (PA3092)

Identification
Name: 2,4-dienoyl-CoA reductase [NADPH]
Synonyms:
  • 2,4-dienoyl coenzyme A reductase
Gene Name: fadH
Enzyme Class:
Biological Properties
General Function: Involved in catalytic activity
Specific Function: Catalyzes the NADP-dependent reduction of 2,4-dienoyl- CoA to yield trans-2- enoyl-CoA
Cellular Location: Not Available
KEGG Pathways: Not Available
KEGG Reactions:
Thumb+Thumb ↔ trans,trans-2,3,4,5-Tetradehydroacyl-CoA+Thumb+Thumb
trans-2,3-Dehydroacyl-CoA + NADP ↔ trans,trans-2,3,4,5-Tetradehydroacyl-CoA + NADPH + Hydrogen ion
ReactionCard
SMPDB Reactions:
trans-Delta2, cis-delta4-decadienoyl-CoA+Thumb+Thumb → Thumb+Thumb
trans-Delta2, cis-delta4-decadienoyl-CoA + NADPH + Hydrogen ion → (2E)-Decenoyl-CoA + NADP
ReactionCard
PseudoCyc/BioCyc Reactions:
Thumb+Thumb ↔ Thumb+Thumb+Thumb
(2E)-Decenoyl-CoA + NADP ↔ Hydrogen ion + trans-Delta2, cis-delta4-decadienoyl-CoA + NADPH
ReactionCard
Complex Reactions:
Trans-2,3-didehydroacyl-CoA+Thumb → trans,trans-2,3,4,5-tetradehydroacyl-CoA+Thumb
Trans-2,3-didehydroacyl-CoA + NADP → trans,trans-2,3,4,5-tetradehydroacyl-CoA + NADPH
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000543(2E)-Decenoyl-CoAMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB000089NADPMetaboCard
PAMDB000615NADPHMetaboCard
PAMDB001410trans-Delta2, cis-delta4-decadienoyl-CoAMetaboCard
GO Classification:
Function
binding
catalytic activity
FMN binding
nucleotide binding
oxidoreductase activity
Process
metabolic process
Gene Properties
Locus tag: PA3092
Strand: -
Entrez Gene ID: 879829
Accession: NP_251782.1
GI: 15598288
Sequence start: 3470764
Sequence End: 3472803
Sequence Length: 2039
Gene Sequence: 
>PA3092
ATGACCGCCGCCGTTCCCTATCCGCACCTGCTCGCCCCGTTGGACCTCGGCTTCACCACCCTGCGCAACCGCACCCTGATGGGGTCCATGCACACTGGCCTGGAAGAGAAGCCGCAGGGCTTCGAGCGCATGGCGGCGTACTTCGCCGAACGCGCCCGCGGTGGCGTCGGCCTGATGGTCACCGGCGGCATCGGCCCGAACGAGGAGGGCGGCGTGTATTCCGGCGCGGCCAAGCTGAGCACGCCGGAAGAGGCGGAGAAGCACAGGATCGTGACCCAGGCGGTGCATGAGGCGGGTGGCAAGATCTGCATGCAGATCCTGCATGCCGGCCGCTACGCCTACAGCCCGAAGCAGGTGGCGCCGAGCGCGATCCAGGCGCCGATCAATCCGTTCAAGCCCAAGGAACTCGACGAGGAAGGCATCGAGAAGCAGATCGCCGACTTCGTCAACTGCGCCAGCCTGGCCCAGGTCGCCGGCTACGACGGCGTCGAGATCATGGGATCGGAAGGCTACTTCATCAACCAGTTCCTCGTGCAGCACACCAACCAGCGCACCGACCGCTGGGGCGGCAGCTACGAGAACCGCATGCGCCTGCCGGTGGAGATCGTCCGCCGGGTGCGCGAGGCGGTGGGGCCGAACTTCATCATCATCTATCGCCTGTCGATGCTCGACCTGGTCGAGGGCGGCAGCAGCTGGGACGAGATCGTGCTGCTGGCGAAGGCCGTCGAGAAGGCCGGCGCGACCCTGATCAATACCGGCATCGGCTGGCACGAGGCGCGCATCCCGACCATCGCCACCAAGGTACCGCGCGCGGCCTTCACCAAGGTCACCGCCAAGCTGCGCGGCGAGGTCGGCATCCCGCTGATCACCACCAACCGCATCAACACTCCCGAGGTGGCGGAGAAGGTCCTGGCCGAGGGCGATGCCGACATGGTCTCCATGGCCCGGCCGTTCCTCGCCGACCCCGATTTCGTCAACAAGGCCGCCGCCGGCCACGCCGAACGGATCAACACCTGTATCGGCTGCAACCAGGCCTGCCTCGACCACACCTTCGGCGGCAAGCTGACCAGTTGCCTGGTCAACCCGCGCGCCTGCCACGAAACCGAGCTGAACTACATCCCCACCACCAGGCCGAAGAAGATCGCCGTGGTCGGCGCCGGCCCGGCCGGCCTGGCCGCCGCCACCGTGGCCGCCGAGCGTGGGCACCGGGTCAGCCTGTTCGACGCCGCCGGCGAGATCGGCGGGCAGTTCAACGTGGCCAAGCGGGTTCCCGGCAAGGAAGAGTTCCACGAGACCCTGCGCTACTTCCGCAACAAGCTGGAGAGCACCGGTGTCGAACTGCACCTGAACCGCCGGGTCGGCGTGGACGACCTGGTCGCGGGCGGCTACGACGAGATCGTCCTCGCCACCGGCATCGTTCCGCGCACACCGGCGATCCCCGGCATCGAGCATCCGAAGGTGATCAGCTACCTGGATGCGATCCTCGAGCGCAAGCCGGTGGGTGGCAAGGTGGCGGTGATCGGCGCCGGCGGCATCGGCTTCGACGTCTCCGAATTCATCACCCATGCCGGTCCGTCCACCAGCCTGGAGCGCGAGGCGTTCTGGAAGGAGTGGGGGATCGATACTCGCCTGGAAGCCCGCGGCGGCATCGCCGGGATCAAGGCCGAGGTGCATCCGGCGGCGCGCCAGGTGTTCCTCCTGCAACGCAAGAAGAGCAAGGTCGGCGACGGCCTCGGCAAGACCACCGGCTGGATCCATCGCGCCGGCCTGAAGAACAAGCAGGTGCAGATGGTGAATGCCGTGGAGTATCTCAGGATCGACGACGCCGGCCTGCATATCCGCGTTGCCGAGGGCGAGCCGCAGGTGCTGCCGGTGGATACCGTGATCGTCTGCGCCGGCCAGGACCCGCTGCGCGAGTTGCAGGACGGCCTGCTGGCGGCCGGCCAGAGCGTGCACCTGATCGGTGGCGCCGACGTCGCCGCCGAGCTGGATGCCAAGCGCGCCATCAACCAGGGTTCGCGCCTGGCCGCCGAACTCTGA
Protein Properties
Protein Residues: 679
Protein Molecular Weight: 73 kDa
Protein Theoretical pI: 7.17
Hydropathicity (GRAVY score): -0.104
Charge at pH 7 (predicted): 1.37
Protein Sequence: 
>PA3092
MTAAVPYPHLLAPLDLGFTTLRNRTLMGSMHTGLEEKPQGFERMAAYFAERARGGVGLMVTGGIGPNEEGGVYSGAAKLSTPEEAEKHRIVTQAVHEAGGKICMQILHAGRYAYSPKQVAPSAIQAPINPFKPKELDEEGIEKQIADFVNCASLAQVAGYDGVEIMGSEGYFINQFLVQHTNQRTDRWGGSYENRMRLPVEIVRRVREAVGPNFIIIYRLSMLDLVEGGSSWDEIVLLAKAVEKAGATLINTGIGWHEARIPTIATKVPRAAFTKVTAKLRGEVGIPLITTNRINTPEVAEKVLAEGDADMVSMARPFLADPDFVNKAAAGHAERINTCIGCNQACLDHTFGGKLTSCLVNPRACHETELNYIPTTRPKKIAVVGAGPAGLAAATVAAERGHRVSLFDAAGEIGGQFNVAKRVPGKEEFHETLRYFRNKLESTGVELHLNRRVGVDDLVAGGYDEIVLATGIVPRTPAIPGIEHPKVISYLDAILERKPVGGKVAVIGAGGIGFDVSEFITHAGPSTSLEREAFWKEWGIDTRLEARGGIAGIKAEVHPAARQVFLLQRKKSKVGDGLGKTTGWIHRAGLKNKQVQMVNAVEYLRIDDAGLHIRVAEGEPQVLPVDTVIVCAGQDPLRELQDGLLAAGQSVHLIGGADVAAELDAKRAINQGSRLAAEL
References
External Links:
Resource Link
Genome ID: PA3092
Entrez Gene ID: 879829
NCBI Protein ID: 15598288
General Reference: PaperBLAST - Find papers about PA3092 and its homologs