Identification
Name: Aconitate hydratase 1
Synonyms:
  • Aconitase 1
  • Citrate hydro-lyase 1
Gene Name: acnA
Enzyme Class:
Biological Properties
General Function: Involved in metabolic process
Specific Function: May have an iron-responsive regulatory function
Cellular Location: Not Available
KEGG Pathways:
KEGG Reactions:
Thumb+ThumbThumb
ThumbThumb+Thumb
ThumbThumb
Thumb+Thumb+ThumbThumb
SMPDB Reactions:
ThumbThumb+Thumb
Thumb+ThumbThumb
Thumb+ThumbThumb
Thumb+ThumbThumb
PseudoCyc/BioCyc Reactions:
Thumb+ThumbThumb
ThumbThumb+Thumb
Complex Reactions:
ThumbThumb
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000025cis-Aconitic acidMetaboCard
PAMDB000034Citric acidMetaboCard
PAMDB006191D-threo-Isocitric acidMetaboCard
PAMDB000604Isocitric acidMetaboCard
PAMDB000142WaterMetaboCard
GO Classification:
Function
4 iron, 4 sulfur cluster binding
binding
iron-sulfur cluster binding
metal cluster binding
Process
metabolic process
Gene Properties
Locus tag: PA1562
Strand: -
Entrez Gene ID: 879412
Accession: NP_250253.1
GI: 15596759
Sequence start: 1700320
Sequence End: 1703052
Sequence Length: 2732
Gene Sequence:
>PA1562
ATGCCTGCTTTGGACAGCCTGAAAACCCTTCGCAGTCTCGCTGTGGACGGCAAGACCTACCACTACTACAGCCTCCCGGAAGCCGCCCGGACCCTGGGCGATCTCGGCAAGCTGCCGATGTCGCTGAAGGTCCTGCTGGAAAACCTCCTGCGCTGGGAGGACGGCAGCACCGTCACCGGCGACGACCTCAAGGCCCTCGCCGGCTGGCTCAGGGAGCGCCGTTCCGACCGCGAGATCCAGTACCGCCCGGCGCGGGTCCTGATGCAGGACTTCACCGGGGTTCCCGCGGTGGTCGACCTGGCCGCCATGCGCGCGGCCATGGCCAAGGCCGGCGGCGACCCGCAGAAGATCAACCCGCTGTCGCCGGTGGACCTGGTCATCGACCACTCGGTGATGGTCGACAAGTTCGCCAGCGAATCGGCCTTCGAACAGAACGTCGAGATCGAGATGCAGCGCAACGGCGAACGCTACGCCTTCCTGCGCTGGGGCCAGAACGCCTTCGACAACTTCAGCGTGGTACCGCCGGGCACCGGCATCTGCCACCAGGTCAACCTGGAGTACCTGGGCCGCACGGTCTGGACCAAGGACGAGGATGGCAGGACCTACGCCTTCCCCGACACCCTGGTCGGCACCGACTCCCACACCACCATGATCAACGGCCTCGGCGTGCTCGGCTGGGGCGTCGGCGGCATCGAGGCGGAAGCCGCCATGCTCGGCCAGCCGGTATCGATGCTGATCCCCGAGGTCATCGGCTTCAAGCTCACCGGCAAGCTGCGCGAGGGCATCACCGCCACCGACCTGGTGCTGACCGTCACGCAGATGCTGCGCAAGAAGGGCGTGGTGGGGAAATTCGTCGAGTTCTACGGCGACGGCCTGGCCGACCTGCCCCTGGCGGACCGCGCCACCATCGCCAACATGGCCCCGGAATACGGCGCCACCTGCGGCTTCTTCCCGGTGGACGAGATCACCCTCGGCTACCTGCGCCTGTCCGGACGTCCGGAAAGCACGGTCAAGCTGGTCGAGGCCTACAGCAAGGAACAGGGCCTGTGGCGCGAGAAGGGCCACGAGCCGGTGTTCACCGACACCCTGCACCTGGACATGGGCGAAGTCGAGGCCAGCCTGGCCGGACCGAAGCGCCCGCAGGACCGCGTGGCCCTGCAGAACGTCGCCAGCGCCTTCAACGAGTTCCTCGGCCTGCAACTGCATCCCTCCAGCACCGAAGAAGGCCGCCTGCTCAGCGAGGGCGGCGGCGGCACCGCGGTCGGCGCCAACGCCGCCTTCGGCGAGATCGACTACCAGCACGACGGCCAGACCCACCGCCTGAAGAACGGCGCGGTGGTGATCGCCGCCATCACCTCCTGCACCAACACCTCCAACCCCAGCGTGATGATGGCCGCCGGCCTGCTGGCGAAGAAGGCAGTGGAGAAAGGCCTGCAACGCAAGCCCTGGGTGAAGAGTTCGCTGGCGCCGGGCTCCAAGGTGGTCACCGACTACTTCAAGGCCGCCGGCCTGACCCGCTACCTCGACGAACTCGGCTTCGATCTGGTCGGCTACGGCTGCACCACCTGCATCGGCAACTCCGGCCCGCTGCTGGAGCCGATCGAGAAAGCCATCCAGCAGGCCGACCTGACCGTCGCCTCGGTACTCTCCGGCAACCGCAACTTCGAAGGCCGCGTGCACCCGTTGGTGAAGACCAACTGGCTGGCCTCGCCGCCGCTGGTGGTGGCCTACGCCCTGGCCGGCAGCGTGCGGATCAACCTCAGCGAGGAACCGCTGGGCACCGGCAAGGACGGCCAGCCGGTCTACCTGAAGGACATCTGGCCGAGCCAGAAGGAAATCGCCGAGGCGATCCAGAAGGTCGACACCGAGATGTTCCACAAGGAGTACGCCGAGGTCTTCGCCGGCGACGAGAAATGGCAGGCGATCCAGGTGCCGCAGTCGGACACCTACGAGTGGCAGGCCGACTCCACCTACATCCAGCATCCACCCTTCTTCGAACACATCGCCGAGGCGCCGCCGGCCATCGCCGACGTCGAGCAGGCGCGGGTGCTGGCGGTGCTGGGCGACTCGGTGACCACCGACCACATCTCCCCTGCCGGCAACATCAAGGCCGACAGCCCGGCCGGCCGCTACCTGCGCGAGCACGGCGTGGAACCGAAGGACTTCAACTCCTACGGCTCCCGTCGCGGCAACCATGAGGTGATGATGCGCGGCACCTTCGCCAACATCCGCATCAAGAACGAGATGCTCGGCGGCGAGGAAGGCGGCAATACCCTGTACGTGCCCAGCGGCGAGAAACTGGCGATCTACGACGCGGCCATGCGTTACCAGGAGGACGGCACCCCGCTGGTGATCGTCGCCGGCAAGGAATACGGCACCGGCTCGTCGCGCGACTGGGCGGCCAAGGGTACCAACCTGCTGGGCGTGAAGGCGGTGATCGCGGAGAGCTTCGAGCGCATCCACCGCTCCAACCTGGTCGGCATGGGCGTGCTGCCGTTGCAGTTCGAGAACGGCCAGGACCGCAAGAGCCTGAAGCTGACCGGCAAGGAGGTGCTGAACATCCGCGGCCTCGGCGGCGAACTCAAACCACACATGCCGCTCAGCGTGGAAGTGACCCGCGAGGACGGCAGCCAGGACAGCTTCAAGGTCCTCTGCCGCATCGACACCCTCAACGAGGTCGAGTATTTCAAGGCCGGCGGCATCCTCCACTACGTGCTGCGCAGCATGCTCTGA
Protein Properties
Protein Residues: 910
Protein Molecular Weight: 99.1 kDa
Protein Theoretical pI: 5.35
Hydropathicity (GRAVY score): -0.218
Charge at pH 7 (predicted): -18.55
Protein Sequence:
>PA1562
MPALDSLKTLRSLAVDGKTYHYYSLPEAARTLGDLGKLPMSLKVLLENLLRWEDGSTVTGDDLKALAGWLRERRSDREIQYRPARVLMQDFTGVPAVVDLAAMRAAMAKAGGDPQKINPLSPVDLVIDHSVMVDKFASESAFEQNVEIEMQRNGERYAFLRWGQNAFDNFSVVPPGTGICHQVNLEYLGRTVWTKDEDGRTYAFPDTLVGTDSHTTMINGLGVLGWGVGGIEAEAAMLGQPVSMLIPEVIGFKLTGKLREGITATDLVLTVTQMLRKKGVVGKFVEFYGDGLADLPLADRATIANMAPEYGATCGFFPVDEITLGYLRLSGRPESTVKLVEAYSKEQGLWREKGHEPVFTDTLHLDMGEVEASLAGPKRPQDRVALQNVASAFNEFLGLQLHPSSTEEGRLLSEGGGGTAVGANAAFGEIDYQHDGQTHRLKNGAVVIAAITSCTNTSNPSVMMAAGLLAKKAVEKGLQRKPWVKSSLAPGSKVVTDYFKAAGLTRYLDELGFDLVGYGCTTCIGNSGPLLEPIEKAIQQADLTVASVLSGNRNFEGRVHPLVKTNWLASPPLVVAYALAGSVRINLSEEPLGTGKDGQPVYLKDIWPSQKEIAEAIQKVDTEMFHKEYAEVFAGDEKWQAIQVPQSDTYEWQADSTYIQHPPFFEHIAEAPPAIADVEQARVLAVLGDSVTTDHISPAGNIKADSPAGRYLREHGVEPKDFNSYGSRRGNHEVMMRGTFANIRIKNEMLGGEEGGNTLYVPSGEKLAIYDAAMRYQEDGTPLVIVAGKEYGTGSSRDWAAKGTNLLGVKAVIAESFERIHRSNLVGMGVLPLQFENGQDRKSLKLTGKEVLNIRGLGGELKPHMPLSVEVTREDGSQDSFKVLCRIDTLNEVEYFKAGGILHYVLRSML
References
External Links:
Resource Link
Genome ID: PA1562
Entrez Gene ID: 879412
NCBI Protein ID: 15596759
General Reference: PaperBLAST - Find papers about PA1562 and its homologs