Identification
Name: cob(I)alamin adenosyltransferase
Synonyms: cobA; btuR
Gene Name: cobO
Enzyme Class: Not Available
Biological Properties
General Function: Not Available
Specific Function: ATP binding, cob(I)yrinic acid a,c-diamide adenosyltransferase activity
Cellular Location: Cytoplasmic
KEGG Pathways:
  • adenosylcobalamin biosynthesis II (late cobalt incorporation) P381-PWY
  • adenosylcobalamin biosynthesis from cobyrinate a,c-diamide I PWY-5509
  • adenosylcobalamin biosynthesis from cobyrinate a,c-diamide II PWY-5508
  • adenosylcobalamin salvage from cobalamin PWY-6268
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
    Thumb
    cob(I)yrinate a,c-diamide + ATP → adenosyl-cobyrinate a,c-diamide + PPPi
    ReactionCard
    PAMDB110477+PAMDB120269PAMDB110425+PAMDB000496
    Complex Reactions: Not Available
    Transports: Not Available
    Metabolites: Not Available
    GO Classification:
    Function
    ATP binding
    cob(I)yrinic acid a,c-diamide adenosyltransferase activity
    Gene Properties
    Locus tag: PA1272
    Strand: +
    Entrez Gene ID: 881408
    Accession: NP_249963.1
    GI: 15596469
    Sequence start: 1383718
    Sequence End: 1384329
    Sequence Length: 611
    Gene Sequence:
    >PA1272
    ATGAACGAATCCCCCGAGAAGGACCAGCGCCACCGCGAGCGGATGGAGCGCAAGAAGGCCGTGGTCGACGAGAAGATCGCCCAGGCCCGCGACGAACGCGGCGTGCTCCTGGTGCATAGCGGCAACGGCAAGGGCAAGAGCAGCTCGGCCTTCGGCATGGTCGCGCGGGCCCTGGGCCATGGCATGAAGGTCGGTGTCGTGCAGTTCATCAAGGGCGCCGCCAGCACCGGCGAGGAAGCCTTCTTCCGGCGCTTCCCCGAGGAAGTCAGCTATCACGTGATGGGCGAGGGCTTCACCTGGGAGACCCAGGACCGCCAGCGCGACATCGCCAAGGCCGAGGCGGCCTGGAAGGTCGCCGCGCAATTGCTGGCCGACCCGGACGTTGGCCTGGTGGTGCTGGACGAACTGAACATCGCCCTCAAGCACGGCTACCTGGAACTGGACAGGGTCCTCGCCGACATCCAGGCGCGCCCGGCCATGCAGCATGTGGTGGTGACCGGTCGCGGCGCGCAGCCGGGGATGATCGAGGCCGCCGACACGGTGACCGAGATGAGCCTGGTCAAGCACGCGTTCAAGGCCGGGATCAAGGCGCAGAAAGGAGTGGAGTTCTGA
    Protein Properties
    Protein Residues: 203
    Protein Molecular Weight: 22.3 kDa
    Protein Theoretical pI: 7.98
    Hydropathicity (GRAVY score): -0.335
    Charge at pH 7 (predicted): 1.69
    Protein Sequence:
    >PA1272
    MNESPEKDQRHRERMERKKAVVDEKIAQARDERGVLLVHSGNGKGKSSSAFGMVARALGHGMKVGVVQFIKGAASTGEEAFFRRFPEEVSYHVMGEGFTWETQDRQRDIAKAEAAWKVAAQLLADPDVGLVVLDELNIALKHGYLELDRVLADIQARPAMQHVVVTGRGAQPGMIEAADTVTEMSLVKHAFKAGIKAQKGVEF
    References
    External Links:
    Resource Link
    Genome ID: PA1272
    Entrez Gene ID: 881408
    NCBI Protein ID: 15596469
    General Reference: PaperBLAST - Find papers about PA1272 and its homologs