Reaction Details
Reaction: Thumb
cob(I)yrinate a,c-diamide + ATP → adenosyl-cobyrinate a,c-diamide + PPPi
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:R344-RXN
References:
  • Bauer CB, Fonseca MV, Holden HM, Thoden JB, Thompson TB, Escalante-Semerena JC, Rayment I (2001). "Three-dimensional structure of ATP:corrinoid adenosyltransferase from Salmonella typhimurium in its free state, complexed with MgATP, or complexed with hydroxycobalamin and MgATP." Biochemistry 40(2);361-74. PMID: 11148030
  • Fonseca MV, Escalante-Semerena JC (2001). "An in vitro reducing system for the enzymic conversion of cobalamin to adenosylcobalamin." J Biol Chem 276(34);32101-8. PMID: 11408479
  • Suh S, Escalante-Semerena JC (1995). "Purification and initial characterization of the ATP:corrinoid adenosyltransferase encoded by the cobA gene of Salmonella typhimurium." J Bacteriol 177(4);921-5. PMID: 7860601
  • Vitols E, Walker GA, Huennekens FM (1966). "Enzymatic conversion of vitamin B-12s to a cobamide coenzyme, alpha-(5,6-dimethylbenzimidazolyl)deoxyadenosylcobamide (adenosyl-B-12)." J Biol Chem 241(7);1455-61. PMID: 5946606