Identification
Name: Aerobic C4-dicarboxylate transport protein
Synonyms: Not Available
Gene Name: dctA
Enzyme Class: Not Available
Biological Properties
General Function: Involved in symporter activity
Specific Function: Responsible for the aerobic transport of the dicarboxylates fumarate, L- and D-malate and to a lesser extent succinate, from the periplasm across the inner membrane
Cellular Location: Cell inner membrane; Multi-pass membrane protein
KEGG Pathways:
KEGG Reactions: Not Available
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
Thumb
C4-dicarboxylate[periplasm] → C4-dicarboxylate[cytosol]
ReactionCard
Complex Reactions: Not Available
Transports:
Metabolites:
PAMDB IDNameView
PAMDB000864(R)-MalateMetaboCard
PAMDB000073Fumaric acidMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB000080L-Aspartic acidMetaboCard
PAMDB000058L-Malic acidMetaboCard
PAMDB000094Orotic acidMetaboCard
PAMDB000107Succinic acidMetaboCard
GO Classification:
Component
cell part
membrane
Function
carboxylic acid transmembrane transporter activity
dicarboxylic acid transmembrane transporter activity
organic acid transmembrane transporter activity
sodium:dicarboxylate symporter activity
substrate-specific transmembrane transporter activity
transmembrane transporter activity
transporter activity
Process
carboxylic acid transport
dicarboxylic acid transport
establishment of localization
organic acid transport
transport
Gene Properties
Locus tag: PA1183
Strand: +
Entrez Gene ID: 880848
Accession: NP_249874.1
GI: 15596380
Sequence start: 1284513
Sequence End: 1285823
Sequence Length: 1310
Gene Sequence:
>PA1183
ATGACCAAACAACCCTTCTACAAGAGCCTGTACGTGCAGGTTCTGGTCGCCATCGCCATCGGTATCGCGCTCGGCCACTGGTACCCGGAAACGGCGGTGGCGATGAAGCCGTTCGGCGACGGCTTCGTCAAACTGATCAAGATGGCCATCGCGCCGATCATCTTCTGCACCGTGGTCACCGGCATCGCCGGCATGCAGAGCATGAAGTCGGTCGGCAAGACCGGCGGCATGGCGCTGCTGTACTTCGAGGTCGTCTCCACCGTGGCCCTGATCATCGGCCTGGTAGTGGTCAACGTGGTCCAGCCGGGCGCCGGCATGCACGTCGACCCGAACACCCTCGACACCAGCAAGATCGCTGCCTACGCCGCTGCCGGCGAGAAGCAGAGCACCGTCGACTTCCTGATGAACGTGATCCCCGGCACCGTGGTCGGCGCGTTCGCCAACGGCGACATCCTCCAGGTCCTGTTCTTCTCCGTGCTCTTCGGCTACGCCCTGCATCGCCTGGGCAGCTACGGCAAGCCGGTGTTCGAGTTCATCGAGCGCGTCTCCCACGTGATGTTCAACATCATCAACGTGATCATGAAGGTCGCCCCGATCGGCGCGTTCGGCGCCATGGCCTTCACCATCGGCGCCTACGGCGTGGGTTCGCTGGTGCAGCTCGGCCAACTGATGCTGTGCTTCTACATCACCTGCATCCTGTTCGTGCTCATCGTCCTCGGCGGCATCGCCCGCGCCCACGGCTTCAGCATCCTGCGCTTCATCAGGTACATCCGCGAGGAACTGCTGATCGTGCTGGGCACCTCGTCTTCCGAGTCGGCTCTGCCGCGGATGATCGACAAGATGGAGAAGCTCGGCTGCAACAAGTCGGTGGTCGGCCTGGTGATTCCCACCGGTTACTCCTTCAACCTCGACGGCACCTCGATCTACCTGACCATGGCCGCGGTGTTCATCGCCCAGGCCACCGATACGCCGATGGACATCACCCACCAGATCACCCTGCTGCTGGTGCTGCTGATCGCTTCCAAGGGCGCCGCCGGCGTCACCGGCAGCGGCTTCATCGTGCTCGCCGCGACCCTTTCCGCCGTCGGCCACCTGCCGGTCGCCGGCCTGGCGCTGATCCTCGGCATCGACCGCTTCATGTCCGAAGCCCGCGCGCTGACCAACCTGGTCGGCAACGGCGTGGCCACGGTAGTGGTTTCCAAGTGGTGCAAGCAGCTCGACGAGGGCACCTTGCAGCGCGAACTGGCCGGCGAGGGCAACGCTTCGTCGCCTGCCAGCGATATTCCGGTGGGCGGCCGCGAAGCGGTCTAA
Protein Properties
Protein Residues: 436
Protein Molecular Weight: 46 kDa
Protein Theoretical pI: 8.2
Hydropathicity (GRAVY score): 0.778
Charge at pH 7 (predicted): 3.52
Protein Sequence:
>PA1183
MTKQPFYKSLYVQVLVAIAIGIALGHWYPETAVAMKPFGDGFVKLIKMAIAPIIFCTVVTGIAGMQSMKSVGKTGGMALLYFEVVSTVALIIGLVVVNVVQPGAGMHVDPNTLDTSKIAAYAAAGEKQSTVDFLMNVIPGTVVGAFANGDILQVLFFSVLFGYALHRLGSYGKPVFEFIERVSHVMFNIINVIMKVAPIGAFGAMAFTIGAYGVGSLVQLGQLMLCFYITCILFVLIVLGGIARAHGFSILRFIRYIREELLIVLGTSSSESALPRMIDKMEKLGCNKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATDTPMDITHQITLLLVLLIASKGAAGVTGSGFIVLAATLSAVGHLPVAGLALILGIDRFMSEARALTNLVGNGVATVVVSKWCKQLDEGTLQRELAGEGNASSPASDIPVGGREAV
References
External Links:
Resource Link
Genome ID: PA1183
Entrez Gene ID: 880848
NCBI Protein ID: 15596380
General Reference: PaperBLAST - Find papers about PA1183 and its homologs