| Identification |
| Name: |
Holliday junction ATP-dependent DNA helicase ruvB |
| Synonyms: |
Not Available |
| Gene Name: |
ruvB |
| Enzyme Class: |
|
| Biological Properties |
| General Function: |
Replication, recombination and repair |
| Specific Function: |
The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday junction migration by localized denaturation and reannealing |
| Cellular Location: |
Cytoplasmic |
| KEGG Pathways: |
|
| KEGG Reactions: |
Not Available |
| SMPDB Reactions: |
Not Available |
| PseudoCyc/BioCyc Reactions: |
|
| Complex Reactions: |
|
| Transports: |
Not Available |
| Metabolites: |
|
| GO Classification: |
| Function |
|---|
| adenyl nucleotide binding | | adenyl ribonucleotide binding | | ATP binding | | binding | | catalytic activity | | DNA binding | | DNA helicase activity | | four-way junction helicase activity | | helicase activity | | hydrolase activity | | hydrolase activity, acting on acid anhydrides | | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | | nucleic acid binding | | nucleoside binding | | nucleoside-triphosphatase activity | | nucleotide binding | | purine nucleoside binding | | pyrophosphatase activity | | Process |
|---|
| cellular macromolecule metabolic process | | DNA metabolic process | | DNA recombination | | DNA repair | | macromolecule metabolic process | | metabolic process |
|
| Gene Properties |
| Locus tag: |
PA0967 |
| Strand: |
+ |
| Entrez Gene ID: |
882028 |
| Accession: |
NP_249658.1 |
| GI: |
15596164 |
| Sequence start: |
1052289 |
| Sequence End: |
1053347 |
| Sequence Length: |
1058 |
| Gene Sequence: |
>PA0967
ATGATCGAGCCTGATCGCCTCATATCCGCCGTTTCCGGTCGCGAACGCGATGAGCAGCTGGACCGCGCCATTCGCCCGCTGAAGCTGGCCGACTACATCGGCCAGCCCAGCGTGCGCGAGCAGATGGAGCTGTTCATCCATGCCGCGCGCGGCCGCCAGGAGGCGCTCGACCATACGCTGATCTTCGGTCCGCCGGGGCTGGGCAAGACGACCCTGGCGAATATCATCGCCCAGGAAATGGGCGTTTCCATCAAGAGTACTTCCGGGCCGGTGCTCGAGCGTCCCGGCGATCTCGCCGCGTTGCTGACCAACCTGGAGGCCGGCGACGTCCTGTTCGTCGACGAGATCCACCGTCTTTCGCCCATCGTCGAAGAAGTGCTGTATCCGGCCATGGAAGATTTCCAGCTGGACATCATGATCGGCGAAGGGCCCGCGGCCCGCTCCATCAAGCTGGACCTGCCGCCGTTCACCCTGGTCGGCGCGACCACCCGTGCCGGCATGCTGACCAATCCACTGCGCGATCGCTTCGGTATCGTCCAGCGCCTGGAGTTCTACAACGTCGAGGACCTGGCGACCATCGTCAGTCGGTCGGCCGGCATTCTCGGCCTGGAGATCGAGCCGCAGGGCGCGGCGGAAATCGCCAAGCGCGCCCGCGGTACGCCGCGAATCGCCAATCGCCTGCTGCGCCGGGTACGCGACTTCGCCGAGGTCCGGGGGCAGGGCGACATTACCCGGGTGATCGCCGACAAGGCATTGAACCTGCTCGATGTGGACGAGCGTGGCTTCGACCACCTCGACCGTCGTCTGTTGCTGACCATGATCGACAAGTTCGATGGCGGGCCTGTAGGAATCGACAACTTGGCTGCGGCGTTGAGCGAGGAGCGGCACACGATCGAAGATGTACTGGAGCCCTATCTGATCCAGCAGGGCTACATCATGCGGACACCGCGGGGGCGCGTGGTAACACGCCATGCGTACCTGCACTTTGGCCTGAATATTCCGAAAAGGTTGGGGCCGGGGGTGACGACGGATCTGTTCACGTCTGAAGATGGTAATTAA |
| Protein Properties |
| Protein Residues: |
352 |
| Protein Molecular Weight: |
38.9 kDa |
| Protein Theoretical pI: |
5.18 |
| Hydropathicity (GRAVY score): |
-0.141 |
| Charge at pH 7 (predicted): |
-8.3 |
| Protein Sequence: |
>PA0967
MIEPDRLISAVSGRERDEQLDRAIRPLKLADYIGQPSVREQMELFIHAARGRQEALDHTLIFGPPGLGKTTLANIIAQEMGVSIKSTSGPVLERPGDLAALLTNLEAGDVLFVDEIHRLSPIVEEVLYPAMEDFQLDIMIGEGPAARSIKLDLPPFTLVGATTRAGMLTNPLRDRFGIVQRLEFYNVEDLATIVSRSAGILGLEIEPQGAAEIAKRARGTPRIANRLLRRVRDFAEVRGQGDITRVIADKALNLLDVDERGFDHLDRRLLLTMIDKFDGGPVGIDNLAAALSEERHTIEDVLEPYLIQQGYIMRTPRGRVVTRHAYLHFGLNIPKRLGPGVTTDLFTSEDGN |
| References |
| External Links: |
|
| General Reference: |
PaperBLAST - Find papers about PA0967 and its homologs
|
