Reaction Details
Reaction: Thumb
a [glutamine-synthetase]-L-tyrosine + ATP = a [glutamine synthetase]-O4-(5'-adenylyl)-L-tyrosine + diphosphate
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:GSADENYLATION-RXN
References:
  • Ebner E, Wolf D, Gancedo C, Elsasser S, Holzer H (1970). "ATP: glutamine synthetase adenylyltransferase from Escherichia coli B. Purification and properties." Eur J Biochem 1970;14(3);535-44. PMID: 4920894
  • Kingdon HS, Shapiro BM, Stadtman ER (1967). "Regulation of glutamine synthetase. 8. ATP: glutamine synthetase adenylyltransferase, an enzyme that catalyzes alterations in the regulatory properties of glutamine synthetase." Proc Natl Acad Sci U S A 1967;58(4);1703-10. PMID: 4867671
  • Mecke D, Wulff K, Liess K, Holzer H (1966). "Characterization of a glutamine synthetase inactivating enzyme from Escherichia coli." Biochem Biophys Res Commun 24(3);452-8. PMID: 5338440
  • Shapiro BM, Stadtman ER (1968). "5'-adenylyl-O-tyrosine. The novel phosphodiester residue of adenylylated glutamine synthetase from Escherichia coli." J Biol Chem 243(13);3769-71. PMID: 4298074
  • Wolf D, Ebner E, Hinze H (1972). "Inactivation, stabilization and some properties of ATP: glutamine synthetase adenylyltransferase from Escherichia coli B." Eur J Biochem 25(2);239-44. PMID: 4402680