Reaction 21854

Reaction Details
Reaction: Thumb
2,3-bis[(3R)-3-hydroxymyristoyl]-α-D-glucosaminyl 1-phosphate + UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-α-D-glucosamine → lipid A disaccharide + UDP + H+
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:LIPIDADISACCHARIDESYNTH-RXN
References:
  • Crowell DN, Reznikoff WS, Raetz CR (1987). "Nucleotide sequence of the Escherichia coli gene for lipid A disaccharide synthase." J Bacteriol 169(12);5727-34. PMID: 2824445
  • Ray BL, Painter G, Raetz CR (1984). "The biosynthesis of gram-negative endotoxin. Formation of lipid A disaccharides from monosaccharide precursors in extracts of Escherichia coli." J Biol Chem 259(8);4852-9. PMID: 6370995