Reaction 21848

Reaction Details
Reaction: Thumb
4'-phosphopantetheine + ATP + H+ → 3'-dephospho-CoA + diphosphate
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:PANTEPADENYLYLTRAN-RXN
References:
  • Geerlof A, Lewendon A, Shaw WV (1999). "Purification and characterization of phosphopantetheine adenylyltransferase from Escherichia coli." J Biol Chem 274(38);27105-11. PMID: 10480925
  • HOAGLAND MB, NOVELLI GD (1954). "Biosynthesis of coenzyme A from phospho-pantetheine and of pantetheine from pantothenate." J Biol Chem 207(2);767-73. PMID: 13163064
  • Izard T, Geerlof A, Lewendon A, Barker JJ (1999). "Cubic crystals of phosphopantetheine adenylyltransferase from Escherichia coli." Acta Crystallogr D Biol Crystallogr 1999;55 ( Pt 6);1226-8. PMID: 10329792
  • Martin DP, Drueckhammer DG (1993). "Separate enzymes catalyze the final two steps of coenzyme A biosynthesis in Brevibacterium ammoniagenes: purification of pantetheine phosphate adenylyltransferase." Biochem Biophys Res Commun 192(3);1155-61. PMID: 8389542
  • NOVELLI GD (1953). "Enzymatic synthesis and structure of CoA." Fed Proc 12(3);675-81. PMID: 13107738