Reaction 21808

Reaction Details
Reaction: Thumb
methylmalonate semialdehyde + coenzyme A + NAD+ + H2O = propanoyl-CoA + hydrogen carbonate + NADH + H+
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:1.2.1.27-RXN
References:
  • Dubourg H, Stines-Chaumeil C, Didierjean C, Talfournier F, Rahuel-Clermont S, Branlant G, Aubry A (2004). "Expression, purification, crystallization and preliminary X-ray diffraction data of methylmalonate-semialdehyde dehydrogenase from Bacillus subtilis." Acta Crystallogr D Biol Crystallogr 60(Pt 8);1435-7. PMID: 15272169
  • Sokatch JR, Sanders LE, Marshall VP (1968). "Oxidation of methylmalonate semialdehyde to propionyl coenzyme A in Pseudomonas aeruginosa grown on valine." J Biol Chem 243(10);2500-6. PMID: 4297649
  • Stines-Chaumeil C, Talfournier F, Branlant G (2006). "Mechanistic characterization of the MSDH (methylmalonate semialdehyde dehydrogenase) from Bacillus subtilis." Biochem J 395(1);107-15. PMID: 16332250