Reaction Details
Reaction: Thumb
precorrin-3B + S-adenosyl-L-methionine → precorrin-4 + S-adenosyl-L-homocysteine + 2 H+
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:2.1.1.131-RXN
References:
  • Debussche L, Thibaut D, Cameron B, Crouzet J, Blanche F (1993). "Biosynthesis of the corrin macrocycle of coenzyme B12 in Pseudomonas denitrificans." J Bacteriol 175(22);7430-40. PMID: 8226690
  • Scott AI, Roessner CA, Stolowich NJ, Spencer JB, Min C, Ozaki SI (1993). "Biosynthesis of vitamin B12. Discovery of the enzymes for oxidative ring contraction and insertion of the fourth methyl group." FEBS Lett 331(1-2);105-8. PMID: 8405386