Identification
Name: precorrin-3 methylase CobJ
Synonyms: cbiH
Gene Name: cobJ
Enzyme Class: Not Available
Biological Properties
General Function: cofactor biosynthetic process, cobalamin biosynthetic process, metabolic process
Specific Function: methyltransferase activity
Cellular Location: Cytoplasmic
KEGG Pathways:
  • adenosylcobalamin biosynthesis II (late cobalt incorporation) P381-PWY
  • cob(II)yrinate a,c-diamide biosynthesis II (late cobalt incorporation) PWY-7376
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
    Thumb
    precorrin-3B + S-adenosyl-L-methionine → precorrin-4 + S-adenosyl-L-homocysteine + 2 H+
    ReactionCard
    Complex Reactions: Not Available
    Transports: Not Available
    Metabolites: Not Available
    GO Classification:
    Function
    methyltransferase activity
    Process
    cofactor biosynthetic process
    cobalamin biosynthetic process
    metabolic process
    Gene Properties
    Locus tag: PA2903
    Strand: -
    Entrez Gene ID: 882638
    Accession: NP_251593.1
    GI: 15598099
    Sequence start: 3256681
    Sequence End: 3258360
    Sequence Length: 1679
    Gene Sequence:
    >PA2903
    GTGAGTGACACCCAGCAGGTTCCGGCCATCGTCATCCTCGGCCAGGGCGCGCTGGATACCGCGCGGCGGGTCCAGGCGCGCTATCCCGGGGCGCTGGTCCACGGGCTCGCCGGGCGGGTCGAGGCCGACCGTTCCTATACGGACTTCGGCGACACCCTGCGCGAACTGTATTGCGCCGACCGCCCGATCGTCGCCCTGTGCGCCGCCGGCATCGTCATTCGCAGCCTGGCGCCGTTGTTGCAACGCAAGGGAGCGGAGCCGCCGGTGCTGGCCCTGGCCGAGGACGGTAGCGCGGTGGTGCCGCTGCTCGGCGGGCTGGCCGGGGTCAACCGGCTGGCGCGGGAAATCGGCGAGGTGCTGGCCGTGGCGCCGGCGATCACCACCAGCGGCGAGCTGCGCTTCGGCACCTGCGTGCTCAACCCGCCCGCCGGTTATGTCCTGGCCGACCTGGAGCAGGGCAAGCGCTTCGTTGCCGATTTGCTCGGTGGCCAGCCGGTGCGCGTCGAGGGTGCCGCCGACTGGCTCGACGCGGCCCGTTTGCCGCGCGACCCGGAGGCAGCGCTGGCGATTCACGTAACGCCCTCGGCGCGTGCGCCGCGGGCCGAGGAACTGCTGATCCATCCGCGCTGCGTGCTGGCGGCGCTCGAACCTGCCGACGCGGCGGCGGACGCGGTGCGCCAGGCGCTGGTCGATGCCGGCCTGGCCGCGGCGGCGCTCGGCGGCTTGCTGGCCGACAGCGCGCGGATGGCCGATCCGCGCCTGCAGGCCGCCGCCGATGCGCTCGGCGTACCGCTGCGCTTCCTGCCGCAGGCCGATCCCGCTGCGCGCCTGCGCCAGGCCTTGCCCGCCGCCGAGCAGGTCGGCGACCGGCTGGCGGTGGCCGCCGCGCCCTTGGCGATGGACCGCATCGGCCAGCGTCGCGGCCGACTCACAGTGATCGGCCTGGGGCCCGGCTGCGCCGAGCTGATGGTGCCTGCGGCGCGGCGGGCACTGGACGAGGCCGAGGACATCCTCGGCTACCAGACCTACGTCGACATGGCCGGACCCTTCCGCGCCGGACAGGTGCTGCATGGCAGCGACAACCGCGAGGAATTGCAGCGCGCCCGGCATGCCTTCGAACTGGCGGCGACGGGCAGGGCGGTGGTGCTGGTATCGTCCGGCGACCCCGGCGTGTTCGCCATGGCCGCCGCGGTGCTGGAAGCCCTGCATGGCGCTGGCGAGCCGGCCTGGGACGCGGTCGAGCTGCGGATCTTCCCTGGCGTCTCGGCGGCCCTGGCCACCGCGGCCAGGGCGGGGGCGCCTCTGGGCCACGATTTCTGCGTGCTGTCGCTGTCCGACAACCTCAAGCCCTGGGAGGTGATCGAGCGGCGCCTGGACCTGGCCGGCGCCGCCGACCTGGCGATGGCTTTCTACAATCCGATCTCGCGGGCGCGGCCCTGGCAACTGGGACGGGCGCTGGAGATCGTCGCCCGCCATCGTTCGCCGCAGACCCTGGTGGTGCTCGGTCGCGACATCGGGCGGCCCGGTGAGCGCCTGCTGCGCACCACCCTGGGCGAGCTGCGTGCGGAGCAGGTGGACATGCGCACCCTGGTGATCATCGGCTCGTCCACTACCCGCAGCTTCCCGCGCGCCGACGGCGAAGCCTGGGTCTACACGCCGCGCTGGTACCCATCGGAATAG
    Protein Properties
    Protein Residues: 559
    Protein Molecular Weight: 58.9 kDa
    Protein Theoretical pI: 5.94
    Hydropathicity (GRAVY score): 0.125
    Charge at pH 7 (predicted): -5.23
    Protein Sequence:
    >PA2903
    MSDTQQVPAIVILGQGALDTARRVQARYPGALVHGLAGRVEADRSYTDFGDTLRELYCADRPIVALCAAGIVIRSLAPLLQRKGAEPPVLALAEDGSAVVPLLGGLAGVNRLAREIGEVLAVAPAITTSGELRFGTCVLNPPAGYVLADLEQGKRFVADLLGGQPVRVEGAADWLDAARLPRDPEAALAIHVTPSARAPRAEELLIHPRCVLAALEPADAAADAVRQALVDAGLAAAALGGLLADSARMADPRLQAAADALGVPLRFLPQADPAARLRQALPAAEQVGDRLAVAAAPLAMDRIGQRRGRLTVIGLGPGCAELMVPAARRALDEAEDILGYQTYVDMAGPFRAGQVLHGSDNREELQRARHAFELAATGRAVVLVSSGDPGVFAMAAAVLEALHGAGEPAWDAVELRIFPGVSAALATAARAGAPLGHDFCVLSLSDNLKPWEVIERRLDLAGAADLAMAFYNPISRARPWQLGRALEIVARHRSPQTLVVLGRDIGRPGERLLRTTLGELRAEQVDMRTLVIIGSSTTRSFPRADGEAWVYTPRWYPSE
    References
    External Links:
    Resource Link
    Genome ID: PA2903
    Entrez Gene ID: 882638
    NCBI Protein ID: 15598099
    General Reference: PaperBLAST - Find papers about PA2903 and its homologs