Reaction 21734

Reaction Details
Reaction: Thumb
a 5,10-methylene-tetrahydrofolate + 3-methyl-2-oxobutanoate + H2O → 2-dehydropantoate + a tetrahydrofolate
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:3-CH3-2-OXOBUTANOATE-OH-CH3-XFER-RXN
References:
  • Powers SG, Snell EE (1976). "Ketopantoate hydroxymethyltransferase. II. Physical, catalytic, and regulatory properties." J Biol Chem 1976;251(12);3786-93. PMID: 6463
  • Teller JH, Powers SG, Snell EE (1976). "Ketopantoate hydroxymethyltransferase. I. Purification and role in pantothenate biosynthesis." J Biol Chem 251(12);3780-5. PMID: 776976