Reaction 21731

Reaction Details
Reaction: Thumb
3-deoxy-D-arabino-heptulosonate-7-phosphate → 3-dehydroquinate + phosphate
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:3-DEHYDROQUINATE-SYNTHASE-RXN
References:
  • Bender SL, Mehdi S, Knowles JR (1989). "Dehydroquinate synthase: the role of divalent metal cations and of nicotinamide adenine dinucleotide in catalysis." Biochemistry 28(19);7555-60. PMID: 2514789
  • Carpenter EP, Hawkins AR, Frost JW, Brown KA (1998). "Structure of dehydroquinate synthase reveals an active site capable of multistep catalysis." Nature 394(6690);299-302. PMID: 9685163
  • Rotenberg SL, Sprinson DB (1970). "Mechanism and stereochemistry of 5-dehydroquinate synthetase." Proc Natl Acad Sci U S A 67(4);1669-72. PMID: 5275368
  • Srinivasan PR, Rothschild J, Sprinson DB (1963). "The enzymic conversion of 3-deoxy-d-arabino-heptulosonic acid 7-phosphate to 5-dehydroquinate." J Biol Chem 238;3176-82. PMID: 14085358