Reaction Details
Reaction: Thumb
a lipid II + H2O → a N-acetylglucosamine--N-acetylmuramyl-(tetrapeptide) pyrophosphoryl-undecaprenol + D-alanine
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:3.4.16.4-RXN
References:
  • Frere JM, Joris B (1985). "Penicillin-sensitive enzymes in peptidoglycan biosynthesis." Crit Rev Microbiol 11(4);299-396. PMID: 3888533
  • Ghuysen JM, Frere JM, Leyh-Bouille M, Nguyen-Disteche M, Coyette J, Dusart J, Joris B, Duez C, Dideberg O, Charlier P (1984). "Bacterial wall peptidoglycan, DD-peptidases and beta-lactam antibiotics." Scand J Infect Dis Suppl 42;17-37. PMID: 6597561