Reaction Details
Reaction: Thumb
AMP + diphosphate = 5-phospho-α-D-ribose 1-diphosphate + adenine
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:ADENPRIBOSYLTRAN-RXN
References:
  • FLAKS JG, ERWIN MJ, BUCHANAN JM (1957). "Biosynthesis of the purines. XVI. The synthesis of adenosine 5'-phosphate and 5-amino-4-imidazolecarboxamide ribotide by a nucleotide pyrophosphorylase." J Biol Chem 228(1);201-13. PMID: 13475309
  • KORNBERG A, LIEBERMAN I, SIMMS ES (1955). "Enzymatic synthesis of purine nucleotides." J Biol Chem 215(1);417-27. PMID: 14392175
  • LUKENS LN, HERRINGTON KA (1957). "Enzymic formation of 6-mercaptopurine tibo tide." Biochim Biophys Acta 24(2);432-3. PMID: 13436452