Argininosuccinate lyase (PA5263)

Identification
Name: Argininosuccinate lyase
Synonyms:
  • ASAL
  • Arginosuccinase
Gene Name: argH
Enzyme Class:
Biological Properties
General Function: Involved in argininosuccinate lyase activity
Specific Function: 2-(N(omega)-L-arginino)succinate = fumarate + L-arginine
Cellular Location: Cytoplasm (Probable)
KEGG Pathways:
KEGG Reactions:
Thumb ↔ Thumb+Thumb
Argininosuccinic acid ↔ L-Arginine + Fumaric acid
ReactionCard
SMPDB Reactions:
Thumb → Thumb+Thumb
Argininosuccinic acid → Fumaric acid + L-Arginine
ReactionCard
PseudoCyc/BioCyc Reactions:
L-arginino-succinate ↔ Thumb+Thumb
L-arginino-succinate ↔ L-Arginine + Fumaric acid
ReactionCard
Complex Reactions: Not Available
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000224Argininosuccinic acidMetaboCard
PAMDB000073Fumaric acidMetaboCard
PAMDB000146L-ArginineMetaboCard
GO Classification:
Function
amidine-lyase activity
argininosuccinate lyase activity
carbon-nitrogen lyase activity
catalytic activity
lyase activity
Process
arginine biosynthetic process
arginine biosynthetic process via ornithine
arginine metabolic process
cellular amino acid and derivative metabolic process
cellular amino acid metabolic process
cellular metabolic process
glutamine family amino acid metabolic process
metabolic process
Gene Properties
Locus tag: PA5263
Strand: +
Entrez Gene ID: 879636
Accession: NP_253950.1
GI: 15600456
Sequence start: 5924596
Sequence End: 5925990
Sequence Length: 1394
Gene Sequence: 
>PA5263
ATGAGCGTAGAGAAGACCAACCAGTCCTGGGGCGGCCGCTTCAGCGAGCCCGTCGACGCCTTCGTCGCCCGTTTCACCGCCTCCGTCGACTTCGACAAGCGTCTCTACCGCCACGACATCATGGGTTCCATCGCCCACGCCACGATGCTGGCCAAGGTCGGCGTGCTGAGCGACGCCGAGCGCGATGCGATCGTCGACGGCCTGCAACAGATCCAGGCGGAAATCGAAGCCGGCAGCTTCGACTGGCGCGTCGACCTGGAAGACGTGCACATGAACATCGAGGCGCGCCTGACCGACCGCATCGGCGTCACCGGCAAGAAGCTCCACACCGGCCGCTCGCGCAACGACCAGGTGGCCACCGACATCCGCCTCTGGCTACGCGACGAGATCGACACCATCCTCGCCGAGATCACCCGCCTGCAGGAGGGCCTGCTGGGCCTGGCCGAAGCGGAAGCCGACACCATCATGCCCGGTTTCACCCACCTGCAGACCGCCCAGCCGGTGACCTTCGGCCACCACCTGCTGGCCTGGTTCGAGATGCTCGGCCGCGACTACGAGCGCCTGGTCGACTGCCGCAAGCGGGTCAACCGCATGCCGCTCGGCTCGGCGGCCCTGGCCGGCACCACCTACCCGATCCAGCGCGAGATCACCTGCCAGTTGCTGGGCTTCGACGCGGTTGGCGGCAACTCCCTGGACGGCGTCTCCGACCGCGACTTCGCCATCGAATTCTGCGCCGCCGCCAGCCTGGCGATGATGCACCTGTCGCGCTTCTCGGAAGAGCTGGTGCTATGGACCAGCGCGCAGTTCCAGTTCATCGACCTGCCCGACCGCTTCTGCACCGGCTCCTCGATCATGCCGCAGAAGAAGAACCCCGACGTGCCGGAGCTGGTACGCGGCAAGTCCGGCCGGGTGTTCGGCGCCCTCACCGGCTTGCTGACCCTGATGAAGGGCCAGCCGCTGGCCTACAACAAGGACAACCAGGAAGACAAGGAACCGCTGTTCGACGCCGCCGACACCCTGCGCGATAGCCTGCGCGCCTTCGCCGACATGGTCCCGGCGATCCGGCCCCGGCGCGAGATCATGCGCGAGGCGGCACGCCGCGGTTTCTCCACCGCCACCGACCTGGCGGACTACCTGGTGCGCAAGGGCCTGCCGTTCCGCGACTGCCACGAGATCGTCGGCCACGCAGTGAAGTACGGCGTAGACAGCGGCAAGGACCTCGCCGAGATGAGCCTCGACGAACTGCGCCGCTTCAGCGAGCAGATCGACGCCGACGTCTTCGACGTGCTGACCCTGGAAGGCTCGGTCAACGCCCGCGACCATATCGGCGGCACCGCGCCGAACCAGGTCCGTGCCGCCGTCGCCCGCGGCAGAAAACTGCTGGCACAGCGCTGA
Protein Properties
Protein Residues: 464
Protein Molecular Weight: 51.6 kDa
Protein Theoretical pI: 5.51
Hydropathicity (GRAVY score): -0.246
Charge at pH 7 (predicted): -9.47
Protein Sequence: 
>PA5263
MSVEKTNQSWGGRFSEPVDAFVARFTASVDFDKRLYRHDIMGSIAHATMLAKVGVLSDAERDAIVDGLQQIQAEIEAGSFDWRVDLEDVHMNIEARLTDRIGVTGKKLHTGRSRNDQVATDIRLWLRDEIDTILAEITRLQEGLLGLAEAEADTIMPGFTHLQTAQPVTFGHHLLAWFEMLGRDYERLVDCRKRVNRMPLGSAALAGTTYPIQREITCQLLGFDAVGGNSLDGVSDRDFAIEFCAAASLAMMHLSRFSEELVLWTSAQFQFIDLPDRFCTGSSIMPQKKNPDVPELVRGKSGRVFGALTGLLTLMKGQPLAYNKDNQEDKEPLFDAADTLRDSLRAFADMVPAIRPRREIMREAARRGFSTATDLADYLVRKGLPFRDCHEIVGHAVKYGVDSGKDLAEMSLDELRRFSEQIDADVFDVLTLEGSVNARDHIGGTAPNQVRAAVARGRKLLAQR
References
External Links:
Resource Link
Genome ID: PA5263
Entrez Gene ID: 879636
NCBI Protein ID: 15600456
General Reference: PaperBLAST - Find papers about PA5263 and its homologs