Ribosomal RNA large subunit methyltransferase E (PA4752)

Identification
Name: Ribosomal RNA large subunit methyltransferase E
Synonyms:
  • 23S rRNA Um2252 methyltransferase
  • Cell division protein ftsJ
  • rRNA (uridine-2'-O-)-methyltransferase
Gene Name: rlmE
Enzyme Class:
Biological Properties
General Function: Translation, ribosomal structure and biogenesis
Specific Function: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
Cellular Location: Cytoplasm (Probable)
KEGG Pathways:
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
    Complex Reactions: Not Available
    Transports: Not Available
    Metabolites:
    PAMDB IDNameView
    PAMDB000205S-AdenosylhomocysteineMetaboCard
    GO Classification:
    Function
    binding
    catalytic activity
    methyltransferase activity
    nucleic acid binding
    RNA methyltransferase activity
    rRNA (uridine) methyltransferase activity
    rRNA methyltransferase activity
    transferase activity
    transferase activity, transferring one-carbon groups
    Process
    cellular macromolecule metabolic process
    cellular metabolic process
    macromolecule metabolic process
    metabolic process
    methylation
    ncRNA metabolic process
    one-carbon metabolic process
    RNA metabolic process
    rRNA metabolic process
    rRNA methylation
    rRNA modification
    rRNA processing
    Gene Properties
    Locus tag: PA4752
    Strand: -
    Entrez Gene ID: 881725
    Accession: NP_253440.1
    GI: 15599946
    Sequence start: 5337900
    Sequence End: 5338523
    Sequence Length: 623
    Gene Sequence: 
    >PA4752
GTGGCCCGCTCCAAAACCAGCCAGCGTTGGCTGAAAGAACATTTCGACGATCCCTACGTGAAGATGGCCCAGCGCGATGGCTATCGCTCGCGTGCCAGCTACAAGCTGCTGGAGATCCAGGAGAAGGACCGCATCCTGCGTCCGGGCATGACCGTGGTCGACCTGGGCGCCGCGCCGGGCGGGTGGTCGCAGGTCACCAGCCGGGTGATCGGCGACCGTGGCCGGCTGATCGCTTCGGACATCCTCGAGATGGACAGCATCCCCGACGTCACCTTCATCCAGGGCGACTTCACCGAGGACGCGGTGTTCGCGCGGATCCTCGAGGCGATCGGCGATCATCCGGTAGACCTTGTGATTTCCGATATGGCCCCCAATATGAGTGGAGTGCGGGCCGCCGACCAGCCGCGCGCCATGTATCTCTGCGAACTGGCGCTGGACCTGGCCGGCCGTGTGCTGCGGCCGGGCGGCGATTTCCTGATCAAGATCTTCCAGGGCGAAGGTTTCGACCAGTACCACAAGCAGGCCCGGGAAATGTTCGACAAGGTACAGATGCGCAAGCCCCTGTCGTCGCGTGATCGTTCGCGGGAACAGTATCTGCTCGCACGCGGCTTTCGCGGGGAATAG
    Protein Properties
    Protein Residues: 207
    Protein Molecular Weight: 23.5 kDa
    Protein Theoretical pI: 7.59
    Hydropathicity (GRAVY score): -0.427
    Charge at pH 7 (predicted): 0.69
    Protein Sequence: 
    >PA4752
MARSKTSQRWLKEHFDDPYVKMAQRDGYRSRASYKLLEIQEKDRILRPGMTVVDLGAAPGGWSQVTSRVIGDRGRLIASDILEMDSIPDVTFIQGDFTEDAVFARILEAIGDHPVDLVISDMAPNMSGVRAADQPRAMYLCELALDLAGRVLRPGGDFLIKIFQGEGFDQYHKQAREMFDKVQMRKPLSSRDRSREQYLLARGFRGE
    References
    External Links:
    Resource Link
    Genome ID: PA4752
    Entrez Gene ID: 881725
    NCBI Protein ID: 15599946
    General Reference: PaperBLAST - Find papers about PA4752 and its homologs