tRNA (uracil-5-)-methyltransferase (PA4720)

Identification
Name: tRNA (uracil-5-)-methyltransferase
Synonyms:
  • tRNA(M-5-U54)-methyltransferase
  • RUMT
Gene Name: trmA
Enzyme Class:
Biological Properties
General Function: Involved in tRNA (uracil-5-)-methyltransferase activity
Specific Function: Catalyzes the formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs
Cellular Location: Not Available
KEGG Pathways: Not Available
KEGG Reactions:
Thumb ↔ Thumb
S-Adenosylmethionine ↔ S-Adenosylhomocysteine
ReactionCard
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
Thumb ↔ Thumb
S-Adenosylmethionine ↔ S-Adenosylhomocysteine
ReactionCard
Thumb
a uracil54 in tRNA + S-adenosyl-L-methionine → a 5-methyluracil54 in tRNA + S-adenosyl-L-homocysteine + H+
ReactionCard
Complex Reactions: Not Available
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000205S-AdenosylhomocysteineMetaboCard
GO Classification:
Function
catalytic activity
methyltransferase activity
RNA methyltransferase activity
S-adenosylmethionine-dependent methyltransferase activity
transferase activity
transferase activity, transferring one-carbon groups
tRNA (uracil-5-)-methyltransferase activity
Process
cellular macromolecule metabolic process
macromolecule metabolic process
metabolic process
ncRNA metabolic process
RNA metabolic process
RNA processing
tRNA metabolic process
tRNA processing
Gene Properties
Locus tag: PA4720
Strand: +
Entrez Gene ID: 881587
Accession: NP_253408.1
GI: 15599914
Sequence start: 5299189
Sequence End: 5300280
Sequence Length: 1091
Gene Sequence: 
>PA4720
ATGAGCCGTCCACAGTTCGACCCCAGCGCCTACGCCGCGCAACTGGAAGACAAGAAGTCCCGCCTCGCCGGATTGCTGGCCCCGTTCGCGGCACCCGCGCCGGAGGTCTTCGAGTCGCCGCGCGAGCATTACCGGCTGCGCGCCGAATTCCGCCTGTGGCGGGAAACCGGCAACGAGAAGCGTCACTACGCGATGTTCGAGCAGGGCGACAAGCACACGCCGATCCTGCTCGAGGATTTCCCCATCGCCAGCCGCCGCATCAACGAACTGATGCCGCGCCTGAAGGCGGCCTGGGCCGACCCGGCGCTGGGCTTCAAGCTGTTCCAGGTGGAGTTTCTCACCACCCTGGCCGGCGACGCGCTGATCACCCTCTGCTACCACCGGCCGATCGACGACGCCTGGCGACAGGCAGCGGAAAAGCTCGCGGCGGAACTGGGCGTGAACCTGGTGGGGCGTTCGCGCGGCAAGCGCATCGTCGTCGGACGCGACTATGTGGAGGAGGAACTGTCGGTCGCCGGCCGGCGCTTCCGCTACCGCCAGCCCGAGGGGGCTTTCACCCAGCCCAACGGCGAGGTCAACCAGAAGATGCTCGGCTGGGCCTACGAGGCGCTCGGCCAGCGCGACGACGACCTGCTCGAACTGTACTGCGGCAACGGCAACTTCACCCTGCCCCTGGCCACCCGGGTACGCAAGGTGCTGGCCACCGAGATCAGCAAGTCCTCGGTCAATGCGGCGCTGGCCAACCTGGCCGACAACGCGGTGGACAACGTCAGCCTGGTGCGCCTGTCGGCCGAAGAGCTGACCCAGGCGCTGAACGAGGTTCGCCCGTTCCGCCGCCTGGCCGACATCGACCTGAAGAGCTACGCCTTCGGCAGTGTCTTCGTCGATCCGCCACGAGCCGGCATGGATCCGGACACCTGCGAGCTGGCCCGACGCTTCGAGCGCATCCTGTACATTTCGTGCAACCCGGAAACCCTGGCGCAGAACATCGCCCAACTGCACGACACGCACCGGATCAGCCGCTGCGCGCTGTTCGACCAGTTCCCCTACACCCACCACATGGAAAGCGGCGTCCTGCTCGAACGCCGCTGA
Protein Properties
Protein Residues: 363
Protein Molecular Weight: 41.2 kDa
Protein Theoretical pI: 6.95
Hydropathicity (GRAVY score): -0.379
Charge at pH 7 (predicted): -0.21
Protein Sequence: 
>PA4720
MSRPQFDPSAYAAQLEDKKSRLAGLLAPFAAPAPEVFESPREHYRLRAEFRLWRETGNEKRHYAMFEQGDKHTPILLEDFPIASRRINELMPRLKAAWADPALGFKLFQVEFLTTLAGDALITLCYHRPIDDAWRQAAEKLAAELGVNLVGRSRGKRIVVGRDYVEEELSVAGRRFRYRQPEGAFTQPNGEVNQKMLGWAYEALGQRDDDLLELYCGNGNFTLPLATRVRKVLATEISKSSVNAALANLADNAVDNVSLVRLSAEELTQALNEVRPFRRLADIDLKSYAFGSVFVDPPRAGMDPDTCELARRFERILYISCNPETLAQNIAQLHDTHRISRCALFDQFPYTHHMESGVLLERR
References
External Links:
Resource Link
Genome ID: PA4720
Entrez Gene ID: 881587
NCBI Protein ID: 15599914
General Reference: PaperBLAST - Find papers about PA4720 and its homologs