| Identification |
| Name: |
Protein methyltransferase hemK |
| Synonyms: |
- M.EcoKHemKP
- Protein-(glutamine-N(5)) MTase hemK
- Protein-glutamine N-methyltransferase hemK
|
| Gene Name: |
hemK |
| Enzyme Class: |
|
| Biological Properties |
| General Function: |
Translation, ribosomal structure and biogenesis |
| Specific Function: |
Methylates the translation termination release factor RF1/PrfA on 'Gln-235' and RF2/PrfB on 'Gln-252' |
| Cellular Location: |
Cytoplasmic |
| KEGG Pathways: |
- reductive acetyl coenzyme A pathway CODH-PWY
|
| KEGG Reactions: |
Not Available |
| SMPDB Reactions: |
Not Available |
| PseudoCyc/BioCyc Reactions: |
| a tetrahydrofolate + a [methyl-Co(III) corrinoid Fe-S protein] ← an N5-methyl-tetrahydrofolate + a [Co(I) corrinoid Fe-S protein] + H +ReactionCard |
|
| Complex Reactions: |
Not Available |
| Transports: |
Not Available |
| Metabolites: |
| PAMDB ID | Name | View |
|---|
| PAMDB000205 | S-Adenosylhomocysteine | MetaboCard | | PAMDB000289 | S-Adenosylmethionine | MetaboCard |
|
| GO Classification: |
| Function |
|---|
| binding | | catalytic activity | | methyltransferase activity | | nucleic acid binding | | protein methyltransferase activity | | transferase activity | | transferase activity, transferring one-carbon groups | | Process |
|---|
| cellular metabolic process | | macromolecule metabolic process | | macromolecule modification | | metabolic process | | methylation | | one-carbon metabolic process | | post-translational protein modification | | protein amino acid alkylation | | protein amino acid methylation | | protein modification process |
|
| Gene Properties |
| Locus tag: |
PA4664 |
| Strand: |
- |
| Entrez Gene ID: |
881353 |
| Accession: |
NP_253353.1 |
| GI: |
15599859 |
| Sequence start: |
5231653 |
| Sequence End: |
5232483 |
| Sequence Length: |
830 |
| Gene Sequence: |
>PA4664
ATGACCACTATCTGTACCCTTCTCAAGGATTCCCAACTGCCCGATTCGCCCAGCGCCCGGCTCGACACCGAGTTGCTGCTGGCGGCGGCGATGGGCAAGCCGCGCAGCTTCCTGCGTACCTGGCCGGAGCGCATCGTGCCGCGCGAGGCCAACGAGCGGTTCGACGACTGGATCGCCCGTCGGCGCAACGGCGAGCCGGTGGCCTACATACTTGGCCACCAGGGCTTCTGGAGCCTGGACCTGGAGGTCGCGCCACACACCCTGATCCCGCGCCCGGACACCGAACTGCTGGTGGAAACCGCGCTGGCGACCCTCGCGGCGGACACCGCTACCGTGCTCGACCTGGGCACCGGCACCGGCGCCATCGCCCTGGCCCTGGCCAGCGAACGGCCGCTGTGGACGGTGACTGCGGTGGACCGCGTGGAAGAGGCCGTGGCGTTGGCCGAGCGCAATCGCCAGCGGCTGCTCCTGGAGAACGTCGAGGTGCGCCGCAGCCACTGGTTCTCCGCTCTCGATGGCCGACGCTTCCGGATGATCGTCGGCAATCCGCCGTATATCCCTGCCAGCGATCCGCACCTGAGCGAGGGCGACGTGCGTTTCGAGCCGAAGAGCGCGCTGGTCGCGGGTAGCGATGGCCTCGACGATATCCGCCAGATCGTCGCCCAGGCGCCGCGGCATTTGCTGGACGAAGGCTGGCTGCTGCTCGAGCACGGCTATGATCAAGGGGCGGCGGTGCGCGAACTGCTCGGCGCCCGCGGCTTCGCCGGGGTACATACGTTGCGCGACCTCGGCGGCAACGAGCGGATCACACTCGGACAATGGGCATGCTGA |
| Protein Properties |
| Protein Residues: |
276 |
| Protein Molecular Weight: |
30.5 kDa |
| Protein Theoretical pI: |
5.21 |
| Hydropathicity (GRAVY score): |
-0.168 |
| Charge at pH 7 (predicted): |
-7.37 |
| Protein Sequence: |
>PA4664
MTTICTLLKDSQLPDSPSARLDTELLLAAAMGKPRSFLRTWPERIVPREANERFDDWIARRRNGEPVAYILGHQGFWSLDLEVAPHTLIPRPDTELLVETALATLAADTATVLDLGTGTGAIALALASERPLWTVTAVDRVEEAVALAERNRQRLLLENVEVRRSHWFSALDGRRFRMIVGNPPYIPASDPHLSEGDVRFEPKSALVAGSDGLDDIRQIVAQAPRHLLDEGWLLLEHGYDQGAAVRELLGARGFAGVHTLRDLGGNERITLGQWAC |
| References |
| External Links: |
|
| General Reference: |
PaperBLAST - Find papers about PA4664 and its homologs
|
