| Identification |
| Name: |
5-carboxy-2-hydroxymuconate semialdehyde dehydrogenase |
| Synonyms: |
hpaE |
| Gene Name: |
hpcC |
| Enzyme Class: |
Not Available |
| Biological Properties |
| General Function: |
carbon utilization, 4-hydroxyphenylacetate metabolic process, cellular catabolic process, metabolic process, oxidation-reduction process, 4-hydroxyphenylacetate catabolic process |
| Specific Function: |
oxidoreductase activity, 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase activity, oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| Cellular Location: |
Cytoplasmic |
| KEGG Pathways: |
|
| KEGG Reactions: |
Not Available |
| SMPDB Reactions: |
Not Available |
| PseudoCyc/BioCyc Reactions: |
| 2-hydroxy-5-carboxymethylmuconate semialdehyde + NAD + + H 2O → 5-carboxymethyl-2-hydroxymuconate + NADH + 2 H +ReactionCard |
|
| Complex Reactions: |
Not Available |
| Transports: |
Not Available |
| Metabolites: |
Not Available |
| GO Classification: |
| Function |
|---|
| oxidoreductase activity | | 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase activity | | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | | Process |
|---|
| carbon utilization | | 4-hydroxyphenylacetate metabolic process | | cellular catabolic process | | metabolic process | | oxidation-reduction process | | 4-hydroxyphenylacetate catabolic process |
|
| Gene Properties |
| Locus tag: |
PA4123 |
| Strand: |
+ |
| Entrez Gene ID: |
880100 |
| Accession: |
NP_252812.1 |
| GI: |
15599318 |
| Sequence start: |
4611013 |
| Sequence End: |
4612473 |
| Sequence Length: |
1460 |
| Gene Sequence: |
>PA4123
ATGATCAAACACTGGATCAATGGCCGCGAGGTCGAAAGCAAGGACGTCTTCGAGAACTACAACCCGGCCACCGGCGAGCTGATCGGCGAGGTCGCCAGCGGCGGCGCGGCGGAAATCGACGCGGCGGTGGCGGCGGCCCGGGAAGCCTTCCCGAAATGGGCCAATACCCCGGCCAAGGAGCGCGCGCGCCTGATGCGCCGGCTCGGCGAGCTGATCGACCGGAACGTGCCGCACCTGGCGGAACTTGAGACCCTCGACACCGGCCTGCCGATCCACCAGACGAAGAACGTGCTGATCCCGCGCGCCTCGCACAACTTCGAGTTCTTCGCCGAAGTCTGCACGCGGATGAACGGGCACAGCTATCCGGTCGACGACCAGATGCTCAACTACACCCTGTACCAGCCGGTAGGCGTCTGCGGCCTGGTCTCGCCGTGGAACGTACCGTTCATGACCGCCACCTGGAAGACCGCGCCGTGCCTGGCGCTGGGCAACACGGCGGTGCTGAAGATGTCCGAGCTGTCGCCGCTGACCGCCAACGAGCTGGGCCGCCTGGTGCACGAGGCGGGCATTCCGCCGGGGGTGTTCAACGTGGTCCAGGGCTACGGCGCCAGCGCCGGCGACGCGCTGGTTCGCCACCGCGACGTGCGCGCGGTGTCCTTCACCGGCGGCACCGCCACCGGGCGACGGATCATGGAGGCGGCCGGGATCAAGAAATACTCGATGGAACTGGGCGGCAAGTCGCCGGTGCTGGTCTTCGAAGACGCCGACCTCGAGCGGGCGCTGGACGCCGCTCTGTTCACCATCTTCTCGCTGAACGGCGAGCGCTGCACCGCCGGCAGTCGCATCTTCGTCCAGGAAAGCGTCTACCCGCAGTTCGTCGCCGAGTTCGCCGCGCGCGCCAGGCGCCTGATCGTCGGCGATCCGCAGGACCCGAAGACCCAGGTCGGCTCGATGATCACCCAGGCCCACTACGACAAGGTCACCGGCTACATCCGCATCGGCCTCGAGGAAGGCGCCACCCTGGTGGCCGGCGGCCTGGAGCGTCCGGCCGGCCTGCCGGCGCACCTGAGCAAGGGGCAGTTCATCCAGCCCACGGTGTTCGCCGACGTGGACAACCGCATGCGCATCGCCCAGGAGGAGATCTTCGGCCCGGTGGTCTGCCTGATCCCGTTCAAGGACGAAGCCGAGGCGCTGCGCCTGGCCAACGACGTGGAATACGGCCTGGCCTCCTACATCTGGACCCAGGACATCGGCAAGGCCCATCGCCTGGCACGCGGCATCGAGGCCGGGATGGTCTTCATCAACAGCCAGAACGTGCGCGACCTGCGCCAGCCGTTCGGCGGGGTGAAGGCCTCGGGCACCGGACGCGAAGGCGGGGAATACAGCTTCGAGGTATTCGCCGAGATCAAGAACGTGTGTATATCCATGGGCAGCCATCACATCCCCCGCTGGGGCGTGTAG |
| Protein Properties |
| Protein Residues: |
486 |
| Protein Molecular Weight: |
53 kDa |
| Protein Theoretical pI: |
6.38 |
| Hydropathicity (GRAVY score): |
-0.098 |
| Charge at pH 7 (predicted): |
-4.28 |
| Protein Sequence: |
>PA4123
MIKHWINGREVESKDVFENYNPATGELIGEVASGGAAEIDAAVAAAREAFPKWANTPAKERARLMRRLGELIDRNVPHLAELETLDTGLPIHQTKNVLIPRASHNFEFFAEVCTRMNGHSYPVDDQMLNYTLYQPVGVCGLVSPWNVPFMTATWKTAPCLALGNTAVLKMSELSPLTANELGRLVHEAGIPPGVFNVVQGYGASAGDALVRHRDVRAVSFTGGTATGRRIMEAAGIKKYSMELGGKSPVLVFEDADLERALDAALFTIFSLNGERCTAGSRIFVQESVYPQFVAEFAARARRLIVGDPQDPKTQVGSMITQAHYDKVTGYIRIGLEEGATLVAGGLERPAGLPAHLSKGQFIQPTVFADVDNRMRIAQEEIFGPVVCLIPFKDEAEALRLANDVEYGLASYIWTQDIGKAHRLARGIEAGMVFINSQNVRDLRQPFGGVKASGTGREGGEYSFEVFAEIKNVCISMGSHHIPRWGV |
| References |
| External Links: |
|
| General Reference: |
PaperBLAST - Find papers about PA4123 and its homologs
|
