Ribosomal RNA large subunit methyltransferase H (PA4004)

Identification
Name: Ribosomal RNA large subunit methyltransferase H
Synonyms:
  • 23S rRNA m3Psi1915 methyltransferase
  • rRNA (pseudouridine-N3-)-methyltransferase rlmH
Gene Name: rlmH
Enzyme Class:
Biological Properties
General Function: Involved in protein homodimerization activity
Specific Function: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. Specific for fully assembled 70S ribosomes
Cellular Location: Cytoplasm (Potential)
KEGG Pathways:
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
    Complex Reactions: Not Available
    Transports: Not Available
    Metabolites:
    PAMDB IDNameView
    PAMDB000205S-AdenosylhomocysteineMetaboCard
    GO Classification:
    Component
    cell part
    cytoplasm
    intracellular part
    Function
    catalytic activity
    methyltransferase activity
    transferase activity
    transferase activity, transferring one-carbon groups
    Process
    cellular macromolecule metabolic process
    macromolecule metabolic process
    metabolic process
    ncRNA metabolic process
    RNA metabolic process
    rRNA metabolic process
    rRNA methylation
    rRNA modification
    rRNA processing
    Gene Properties
    Locus tag: PA4004
    Strand: -
    Entrez Gene ID: 878973
    Accession: NP_252693.1
    GI: 15599199
    Sequence start: 4485349
    Sequence End: 4485816
    Sequence Length: 467
    Gene Sequence: 
    >PA4004
ATGCGGTTGCGCCTGATCGCGGTTGGCTCGCGCATGCCTCGCTGGGTCGAGGAAGGCTGGCAGGAATACGTCAAGCGCCTGCCGGCCGAGCTGTCCCTCGAACTGGTGGAGATCCCGCTCAACACCCGCGGCAAGAACGCCGACGTGGCGCGCCTGATCCGTCAGGAAGGCGAGGCCATGCTGGCGCGCGTGCAGCCGGGGGAACGGGTGGTGACCCTGGAGGTCGAAGGTCGGCCCTGGAGCACCGAGCAACTGGCTCGCGAACTGGATCGCTGGCGTCTCGACGCACGCACCGTGAATCTCATGGTCGGCGGCCCGGAAGGGCTGGCGCCGGAGGTCTGCGCGCGCAGCGAGCAGCGCTGGTCGCTGTCGCCGTTGACGCTGCCGCACCCGTTGGTGCGGATCCTGGTCGGCGAGCAGATCTACCGGGCCTGGACCGTATTGTCCGGGCACCCCTACCACAAATAG
    Protein Properties
    Protein Residues: 155
    Protein Molecular Weight: 17.8 kDa
    Protein Theoretical pI: 9.17
    Hydropathicity (GRAVY score): -0.35
    Charge at pH 7 (predicted): 2.69
    Protein Sequence: 
    >PA4004
MRLRLIAVGSRMPRWVEEGWQEYVKRLPAELSLELVEIPLNTRGKNADVARLIRQEGEAMLARVQPGERVVTLEVEGRPWSTEQLARELDRWRLDARTVNLMVGGPEGLAPEVCARSEQRWSLSPLTLPHPLVRILVGEQIYRAWTVLSGHPYHK
    References
    External Links:
    Resource Link
    Genome ID: PA4004
    Entrez Gene ID: 878973
    NCBI Protein ID: 15599199
    General Reference: PaperBLAST - Find papers about PA4004 and its homologs