Apolipoprotein N-acyltransferase (PA3984)

Identification
Name: Apolipoprotein N-acyltransferase
Synonyms:
  • ALP N-acyltransferase
  • Copper homeostasis protein cutE
Gene Name: lnt
Enzyme Class: Not Available
Biological Properties
General Function: Involved in N-acyltransferase activity
Specific Function: Transfers the fatty acyl group on membrane lipoproteins
Cellular Location: Cell inner membrane; Multi-pass membrane protein
KEGG Pathways:
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
    Complex Reactions:
    applipoprotein+Thumb → Thumb+lipoprotein
    applipoprotein + PE(14:0/14:0) → 2-Acyl-sn-glycero-3-phosphoethanolamine (N-C16:0) + lipoprotein
    ReactionCard
    applipoprotein+Thumb → Thumb+lipoprotein
    applipoprotein + PG(16:0/16:0) → 2-Acyl-sn-glycero-3-phosphoglycerol (N-C16:0) + lipoprotein
    ReactionCard
    Transports: Not Available
    Metabolites:
    PAMDB IDNameView
    PAMDB0015512-Acyl-sn-glycero-3-phosphoethanolamine (N-C16:0)MetaboCard
    PAMDB0015582-Acyl-sn-glycero-3-phosphoglycerol (N-C16:0)MetaboCard
    PAMDB000751PE(14:0/14:0)MetaboCard
    PAMDB000791PG(16:0/16:0)MetaboCard
    GO Classification:
    Component
    cell part
    integral to membrane
    intrinsic to membrane
    membrane part
    Function
    acyltransferase activity
    catalytic activity
    hydrolase activity
    hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
    N-acyltransferase activity
    transferase activity
    transferase activity, transferring acyl groups
    transferase activity, transferring acyl groups other than amino-acyl groups
    Process
    biosynthetic process
    cellular macromolecule biosynthetic process
    lipoprotein biosynthetic process
    macromolecule biosynthetic process
    metabolic process
    nitrogen compound metabolic process
    Gene Properties
    Locus tag: PA3984
    Strand: +
    Entrez Gene ID: 878907
    Accession: NP_252673.1
    GI: 15599179
    Sequence start: 4463904
    Sequence End: 4465439
    Sequence Length: 1535
    Gene Sequence: 
    >PA3984
ATGCGTTGGATTTCTCGTCCCGGCTGGCCCGGACACCTGCTGGCACTCGCCGCAGGCGCGCTCACACCCCTGGCCCTGGCGCCCTTCGACTACTGGCCGCTGGCGATCCTCTCGATCGCCCTGCTCTATCTCGGCTTGCGCGGCCTTCCCGGCAAGTCCGCCCTGTGGCGCGGCTGGTGGTACGGTTTCGGCGCGTTCGGCGCCGGCACCAGCTGGATCTACGTCAGTATCCATGACTACGGCGCCGCCTCGGTGCCGCTGGCAAGCCTCCTCATGCTCGGCTTCACCGCCGGCGTCGCCTTCTTCTTCGCCCTGCCGGCCTGGCTGTGGGCGCGCTGCCTGCGCCGCGACAACGCGCCGCTGGGCGACGCCCTGGCGTTCGCCGCCCTGTGGCTGGCACTGGAGCTGTTCCGCAGTTGGTTCCTTACCGGTTTCCCCTGGCTCTACGCCGGCTATAGCCAGTTGCAGGGACCGCTGGCCGGGCTGGTACCGGTGGGCGGCGTATGGCTGTCCTCCTTCGTCATCGCCCTCAGCGCGGCCCTGCTGGTGAACCTGCCGCGCCTCTTCCCGCACGGTGCCAGCCTGCTTCTGGGGCTGGTCCTGCTGCTCGGCCCGTGGGCGGCCGGCCTCTATCTCAAGGGCCACGCCTGGACCCATTCGGCCGGCGAACCGCTGAGGGTAGTGGCGATCCAGGGCAACATCGCCCAGGAGCTGAAATGGGACCCGAATCAGGTCCGCGCGCAACTCGACCTCTACCGCGACCTGAGCCTGCCGCAGCAGGACGTCGACCTGATCGTCTGGCCGGAAACCGCGGTGCCGATTCTCCAGGACATGGCCAGCGGCTACCTCGGCGCCATGGGCCAGGTCGCCGACGAGAAGAACGCCGCGCTGATCACCGGGGTCCCGGTGCGTGAACGTCTCGCCGACGGCAAGAGTCGCTACTTCAACGGCATCACCGTGGTCGGCGAAGGCGCGGGCACCTACCTCAAGCAGAAGCTGGTGCCGTTCGGCGAGTACGTGCCGCTGCAGGACCTGCTGCGCGGCCTGATCGCCTTCTTCGACCTGCCGATGTCCGACTTCGCTCGCGGTCCGGCCGACCAGCCGCTGCTCAAGGCCAAGGGCTACCAGATCGCCCCGTACATCTGCTACGAAGTGGTCTACCCGGAGTTCGCCGCCGCGCTCGCGGCGCAGAGCCAGGTGTTGCTGACAGTGAGCAACGACACCTGGTTCGGCACTTCCATAGGCCCTTTGCAGCACCTGCAGATGGCACAGATGCGCGCCCTGGAAAGCGGTCGCTGGATGATCCGCGCGACCAACAACGGCGTCACCGGCCTGATCGATCCCTATGGCCGGATCGTCCGGCAGATCCCGCAGTTCCAGCAGGGCATCCTGCGCGGCGAGGTGATTCCCATGCAGGGCCTGACGCCCTATCTGCAATACCGCGTCTGGCCGCTGGCCGGGTTGGCCGGCGTGCTGCTGCTATGGGCTCTGCTCGGCCGCCAGTTGCGTCCGCAGGAGCGACGCCTGTTCGGCTGA
    Protein Properties
    Protein Residues: 511
    Protein Molecular Weight: 56 kDa
    Protein Theoretical pI: 9.36
    Hydropathicity (GRAVY score): 0.364
    Charge at pH 7 (predicted): 7.37
    Protein Sequence: 
    >PA3984
MRWISRPGWPGHLLALAAGALTPLALAPFDYWPLAILSIALLYLGLRGLPGKSALWRGWWYGFGAFGAGTSWIYVSIHDYGAASVPLASLLMLGFTAGVAFFFALPAWLWARCLRRDNAPLGDALAFAALWLALELFRSWFLTGFPWLYAGYSQLQGPLAGLVPVGGVWLSSFVIALSAALLVNLPRLFPHGASLLLGLVLLLGPWAAGLYLKGHAWTHSAGEPLRVVAIQGNIAQELKWDPNQVRAQLDLYRDLSLPQQDVDLIVWPETAVPILQDMASGYLGAMGQVADEKNAALITGVPVRERLADGKSRYFNGITVVGEGAGTYLKQKLVPFGEYVPLQDLLRGLIAFFDLPMSDFARGPADQPLLKAKGYQIAPYICYEVVYPEFAAALAAQSQVLLTVSNDTWFGTSIGPLQHLQMAQMRALESGRWMIRATNNGVTGLIDPYGRIVRQIPQFQQGILRGEVIPMQGLTPYLQYRVWPLAGLAGVLLLWALLGRQLRPQERRLFG
    References
    External Links:
    Resource Link
    Genome ID: PA3984
    Entrez Gene ID: 878907
    NCBI Protein ID: 15599179
    General Reference: PaperBLAST - Find papers about PA3984 and its homologs