Ribosomal RNA large subunit methyltransferase F (PA3840)

Identification
Name: Ribosomal RNA large subunit methyltransferase F
Synonyms:
  • 23S rRNA mA1618 methyltransferase
  • rRNA adenine N-6-methyltransferase
Gene Name: rlmF
Enzyme Class:
Biological Properties
General Function: Involved in rRNA (adenine-N6-)-methyltransferase activity
Specific Function: Specifically methylates the adenine in position 1618 of 23S rRNA
Cellular Location: Cytoplasm (Potential)
KEGG Pathways: Not Available
KEGG Reactions:
Thumb+rRNA ↔ Thumb+rRNA containing N6-methyladenine
S-Adenosylmethionine + rRNA ↔ S-Adenosylhomocysteine + rRNA containing N6-methyladenine
ReactionCard
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
Thumb+rRNA ↔ Thumb+rRNA containing N6-methyladenine
S-Adenosylmethionine + rRNA ↔ S-Adenosylhomocysteine + rRNA containing N6-methyladenine
ReactionCard
Complex Reactions: Not Available
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000205S-AdenosylhomocysteineMetaboCard
PAMDB000289S-AdenosylmethionineMetaboCard
GO Classification:
Component
cell part
cytoplasm
intracellular part
Function
catalytic activity
methyltransferase activity
N-methyltransferase activity
rRNA (adenine-N6-)-methyltransferase activity
transferase activity
transferase activity, transferring one-carbon groups
Process
cellular macromolecule metabolic process
macromolecule metabolic process
metabolic process
ncRNA metabolic process
RNA metabolic process
rRNA metabolic process
rRNA processing
Gene Properties
Locus tag: PA3840
Strand: +
Entrez Gene ID: 879836
Accession: NP_252529.1
GI: 15599035
Sequence start: 4302041
Sequence End: 4303051
Sequence Length: 1010
Gene Sequence: 
>PA3840
ATGCCCCGCCCGACCAGCCCGCATCCCGACGCCGAGCGCAAGAGCGCCAGCCCGCTGCACCCGCGCAATCGCCACCTGGGACGCTACGACTTTCCGCGCCTGATCGCCGGCAGCCCGGAACTGGAGCGCTTCGTCATCCTCAATCCGTACGGCAGGCAGAGCATCGACTTCGCCGATCCGGCGGCGGTGAAAGCCTTCAACCGCGCGCTGCTGCAACAGTTCTACGACGTACGCGAGTGGGATATACCCGATGGTTACCTGTGCCCGCCCATCCCCGGTCGCGCCGACTACCTGCACTACCTGGCCGACCTGCTCGGCGCCAGCCACGATGGCCTGATTCCACGCGGTCCCGGCCTGCGTGCGCTGGACGTCGGAACCGGAGCCAACTGCATCTACCCGCTGCTCGGCCACCACGAATACGGCTGGCGCTTCGTCGGCGCCGACATCGACCCGCAATCGCTGGCCTCGGCCGCTGCGATCCTCGCCGCCAACCCACGCTTCGCCGCTGCCATCGAGTTGCGCCGGCAGCCTGATCGCAGGCAGATATTCCAGGGCCTGATCGGCGTCGATGAGCGCTTCGACATGACCCTCTGCAACCCGCCCTTCCACGCCTCGCTGGACGAAGCCACGCGCGGCAGCCGGCGCAAGTGGAAGAACCTCGGCAAGCTCGACCCGACCCGTACCCTGCCGCTACTGAACTTTGGCGGCCAGGGCGCCGAGCTGTACTGCGAGGGCGGCGAAGCGGCCTTCCTGGCCGGCATGGCCGAGGAAAGCCGGGCGTTCGCCACGCAGGTGTTCTGGTTCACCACCCTGGTATCCAAGGCGAGCAACCTGCCGAACCTCCAGGAGCGCCTGAAGACGTTGGGCGCCAGCGATATCCGCGTGGTGGACATGGCCCAGGGACAGAAGCAGAGCCGTTTCGTCGCCTGGACCTACCTCGACAAGAAGCAGCGCCGGGCCTGGCGCAAGGAGCGCTGGACAGCAGCCCTCCTGGAACCACTGGGCGAATAG
Protein Properties
Protein Residues: 336
Protein Molecular Weight: 37.6 kDa
Protein Theoretical pI: 9.08
Hydropathicity (GRAVY score): -0.405
Charge at pH 7 (predicted): 6.8
Protein Sequence: 
>PA3840
MPRPTSPHPDAERKSASPLHPRNRHLGRYDFPRLIAGSPELERFVILNPYGRQSIDFADPAAVKAFNRALLQQFYDVREWDIPDGYLCPPIPGRADYLHYLADLLGASHDGLIPRGPGLRALDVGTGANCIYPLLGHHEYGWRFVGADIDPQSLASAAAILAANPRFAAAIELRRQPDRRQIFQGLIGVDERFDMTLCNPPFHASLDEATRGSRRKWKNLGKLDPTRTLPLLNFGGQGAELYCEGGEAAFLAGMAEESRAFATQVFWFTTLVSKASNLPNLQERLKTLGASDIRVVDMAQGQKQSRFVAWTYLDKKQRRAWRKERWTAALLEPLGE
References
External Links:
Resource Link
Genome ID: PA3840
Entrez Gene ID: 879836
NCBI Protein ID: 15599035
General Reference: PaperBLAST - Find papers about PA3840 and its homologs