| Identification |
| Name: |
1-deoxy-D-xylulose 5-phosphate reductoisomerase |
| Synonyms: |
- DXP reductoisomerase
- 1-deoxyxylulose-5-phosphate reductoisomerase
- 2-C-methyl-D-erythritol 4-phosphate synthase
|
| Gene Name: |
dxr |
| Enzyme Class: |
|
| Biological Properties |
| General Function: |
Involved in 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity |
| Specific Function: |
Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) |
| Cellular Location: |
Not Available |
| KEGG Pathways: |
|
| KEGG Reactions: |
|
| SMPDB Reactions: |
|
NADPH | + |  | + | 1-Deoxy-D-xylulose 5-phosphate | + |  | + |  | → |  | + | 2-C-methyl-D-erythritol 4-phosphate |
| |
|
| PseudoCyc/BioCyc Reactions: |
|
| Complex Reactions: |
Not Available |
| Transports: |
Not Available |
| Metabolites: |
|
| GO Classification: |
| Function |
|---|
| 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity | | binding | | catalytic activity | | cation binding | | ion binding | | metal ion binding | | oxidoreductase activity | | oxidoreductase activity, acting on CH-OH group of donors | | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | | Process |
|---|
| cellular lipid metabolic process | | isoprenoid biosynthetic process | | isoprenoid metabolic process | | lipid metabolic process | | metabolic process | | oxidation reduction | | primary metabolic process |
|
| Gene Properties |
| Locus tag: |
PA3650 |
| Strand: |
- |
| Entrez Gene ID: |
880464 |
| Accession: |
NP_252340.1 |
| GI: |
15598846 |
| Sequence start: |
4088904 |
| Sequence End: |
4090094 |
| Sequence Length: |
1190 |
| Gene Sequence: |
>PA3650
ATGAGTCGACCGCAGCGGATCAGCGTGCTCGGCGCGACCGGCTCGATCGGCCTGAGCACCCTGGACGTCGTCCAGCGTCATCCCGATCGTTACGAAGCCTTCGCCCTGACTGGCTTCAGCCGCCTGGCCGAACTCGAGGCGCTGTGCCTCAGGCACCGCCCCGTCTATGCGGTGGTGCCGGAGCAGGCCGCGGCGATTGCCTTGCAGGGCTCGCTCGCCGCGGCGGGTATCCGCACCCGGGTGCTGTTCGGCGAGCAGGCGTTGTGCGAAGTGGCCAGCGCGCCCGAAGTGGACATGGTAATGGCGGCCATCGTCGGCGCCGCCGGGCTGCCGTCGACCCTGGCGGCCGTCGAGGCCGGCAAGCGCGTACTGCTGGCCAACAAGGAGGCGCTGGTGATGTCCGGCGCGCTGTTCATGCAGGCGGTCAAGCGCAGCGGCGCGGTGCTCCTGCCGATCGACAGCGAGCACAACGCGATCTTCCAGTCGCTGCCGCGCAATTATGCCGATGGCCTGGAGCGGGTCGGCGTGCGCCGGATCCTCTTGACCGCCTCCGGCGGCCCGTTCCGCGAGACGCCGCTGGAGCAACTCGCTTCGGTGACGCCGGAGCAGGCTTGTGCGCACCCGAACTGGTCGATGGGGCGTAAGATTTCCGTCGACTCCGCCAGCATGATGAACAAGGGGCTCGAACTGATCGAGGCGTGCTGGCTGTTCGACGCCCAGCCGAGCCAGGTCGAGGTGGTGATCCACCCGCAGAGCGTGATCCACTCGATGGTGGACTACGTCGACGGTTCGGTGATCGCCCAGCTCGGCAATCCGGACATGCGCACGCCGATTTCCTATGCCATGGCCTGGCCGGAGCGAATCGATTCCGGCGTTTCGCCGCTGGATATGTTCGCCGTCGGTCGCCTGGATTTCCAGCGCCCCGACGAGCAGCGCTTCCCCTGCCTGCGCCTGGCGAGCCAGGCCGCGGAAACCGGCGGCAGCGCCCCGGCCATGCTGAATGCCGCGAACGAGGTGGCCGTGGCCGCATTTCTCGAGCGGCACATCCGCTTCAGCGACATCGCGGTTATCATCGAGGACGTGCTGAACCGCGAGGCGGTGACCGCAGTCGAATCGCTCGATCAGGTCCTGGCTGCCGATCGCCGCGCGCGTTCGGTCGCCGGGCAATGGTTGACCCGGCACGCCGGCTAG |
| Protein Properties |
| Protein Residues: |
396 |
| Protein Molecular Weight: |
42.5 kDa |
| Protein Theoretical pI: |
5.65 |
| Hydropathicity (GRAVY score): |
0.147 |
| Charge at pH 7 (predicted): |
-6.21 |
| Protein Sequence: |
>PA3650
MSRPQRISVLGATGSIGLSTLDVVQRHPDRYEAFALTGFSRLAELEALCLRHRPVYAVVPEQAAAIALQGSLAAAGIRTRVLFGEQALCEVASAPEVDMVMAAIVGAAGLPSTLAAVEAGKRVLLANKEALVMSGALFMQAVKRSGAVLLPIDSEHNAIFQSLPRNYADGLERVGVRRILLTASGGPFRETPLEQLASVTPEQACAHPNWSMGRKISVDSASMMNKGLELIEACWLFDAQPSQVEVVIHPQSVIHSMVDYVDGSVIAQLGNPDMRTPISYAMAWPERIDSGVSPLDMFAVGRLDFQRPDEQRFPCLRLASQAAETGGSAPAMLNAANEVAVAAFLERHIRFSDIAVIIEDVLNREAVTAVESLDQVLAADRRARSVAGQWLTRHAG |
| References |
| External Links: |
|
| General Reference: |
PaperBLAST - Find papers about PA3650 and its homologs
|
