Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase (PA3553)

Identification
Name: Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase
Synonyms:
  • Polymyxin resistance protein pmrF
  • Undecaprenyl-phosphate Ara4FN transferase
  • Ara4FN transferase
Gene Name: arnC
Enzyme Class:
Biological Properties
General Function: beta-L-Ara4N-lipid A biosynthetic process
Specific Function: phosphotransferase activity, for other substituted phosphate groups, transferase activity, transferring glycosyl groups
Cellular Location: Cell inner membrane; Multi-pass membrane protein
KEGG Pathways:
  • Amino sugar and nucleotide sugar metabolism pae00520
KEGG Reactions:
Thumb+Thumb ↔ Undecaprenyl phosphate alpha-L-Ara4FN+Thumb+Thumb
Uridine 5''-diphospho-{beta}-4-deoxy-4-formamido-L-arabinose + Di-trans,poly-cis-undecaprenyl phosphate ↔ Undecaprenyl phosphate alpha-L-Ara4FN + Uridine 5'-diphosphate + 4-Amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate
ReactionCard
SMPDB Reactions:
Thumb+di-trans,octa-cis-undecaprenyl phosphate → Thumb+Thumb
UDP-4-Deoxy-4-formamido-beta-L-arabinose + di-trans,octa-cis-undecaprenyl phosphate → Uridine 5'-diphosphate + 4-deoxy-4-formamido-α-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate
ReactionCard
PseudoCyc/BioCyc Reactions:
Thumb+Thumb → 4-deoxy-4-formamido-α-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate+Thumb
Uridine 5''-diphospho-{beta}-4-deoxy-4-formamido-L-arabinose + Di-trans,poly-cis-undecaprenyl phosphate → 4-deoxy-4-formamido-α-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate + Uridine 5'-diphosphate
ReactionCard
Complex Reactions:
Thumb+Thumb → Thumb+Thumb
Undecaprenyl phosphate + Uridine 5''-diphospho-{beta}-4-deoxy-4-formamido-L-arabinose → Undecaprenyl phosphate-4-amino-4-formyl-L-arabinose + Uridine 5'-diphosphate
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB0034904-Amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphateMetaboCard
PAMDB0063584-deoxy-4-formamido-α-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphateMetaboCard
PAMDB001145Di-trans,poly-cis-undecaprenyl phosphateMetaboCard
PAMDB003589UDP-4-Deoxy-4-formamido-beta-L-arabinoseMetaboCard
PAMDB001054Undecaprenyl phosphateMetaboCard
PAMDB001761Undecaprenyl phosphate-4-amino-4-formyl-L-arabinoseMetaboCard
PAMDB001763Uridine 5''-diphospho-{beta}-4-deoxy-4-formamido-L-arabinoseMetaboCard
PAMDB000123Uridine 5'-diphosphateMetaboCard
GO Classification:
Function
phosphotransferase activity, for other substituted phosphate groups
transferase activity, transferring glycosyl groups
Process
beta-L-Ara4N-lipid A biosynthetic process
Gene Properties
Locus tag: PA3553
Strand: +
Entrez Gene ID: 878472
Accession: NP_252243.1
GI: 15598749
Sequence start: 3981005
Sequence End: 3982024
Sequence Length: 1019
Gene Sequence: 
>PA3553
ATGAAGCCCTATCCGATCGACCTGGTCTCGGTGGTGATCCCGGTCTACAACGAGGAAGCCAGCCTGCCCGAACTGCTGCGCCGCACCGAGGCCGCCTGCCTGGAGCTGGGCCGCGCCTTCGAGATCGTGCTGGTCGACGACGGCAGCCGCGACCGCTCCGCGGAACTCTTGCAGGCCGCCGCCGAACGCGACGGCAGCGCCGTGGTGGCGGTGATCCTCAACCGCAACTACGGCCAGCACGCGGCGATCCTCGCCGGCTTCGAACAGTCCCGTGGAGACCTGGTGATCACCCTCGATGCCGACCTGCAGAACCCGCCGGAGGAAATCCCGCGCCTGGTGGAGCGCGCCGCGCAGGGCTACGACGTGGTCGGCAGCATCCGCGCCGAGCGCCAGGACTCGGCCTGGCGGCGCTGGCCTTCGCGCCTGGTGAACCTGGCGGTGCAGCGCTCCACCGGGGTCGCCATGCACGACTACGGCTGCATGCTGCGCGCCTACCGGCGCAGCATCGTCGAAGCGATGCTGGCCTGCCGCGAACGCAGTACCTTCATCCCGATCCTGGCCAACGGCTTCGCCCGGCATACCTGCGAGATCCGCGTCGCCCACGCCGAGCGCGCCCACGGCGAATCGAAATACAGCGCGATGCGCCTGCTCAACCTGATGTTCGACCTGGTCACCTGCATGACCACCACGCCGCTGCGCCTGCTCAGCCTGGTCGGCGGCGGCATGGCCCTGGCCGGCTTCCTCTTCGCCCTGTTCCTCCTCGTGCTGCGCCTGGCCTTCGGCGCCGCCTGGGCCGGCAACGGCCTGTTCGTGCTGTTCGCCGTGCTGTTCATGTTCAGCGGCGTGCAGTTGCTCGGCATGGGCCTGCTCGGCGAGTACCTCGGGCGCATGTACAGCGACGTGCGCGCGCGGCCGCGCTTCTTCATCGAGCGCGTGGTCCGCGCAACGCCCTCCGCGCTTCCCTCGGCCCTGCAGCGGGCCGGTTTCACCTCTTCATCCAGCGAGCCTTCCACGCCATGA
Protein Properties
Protein Residues: 339
Protein Molecular Weight: 37.3 kDa
Protein Theoretical pI: 8.21
Hydropathicity (GRAVY score): 0.193
Charge at pH 7 (predicted): 3.05
Protein Sequence: 
>PA3553
MKPYPIDLVSVVIPVYNEEASLPELLRRTEAACLELGRAFEIVLVDDGSRDRSAELLQAAAERDGSAVVAVILNRNYGQHAAILAGFEQSRGDLVITLDADLQNPPEEIPRLVERAAQGYDVVGSIRAERQDSAWRRWPSRLVNLAVQRSTGVAMHDYGCMLRAYRRSIVEAMLACRERSTFIPILANGFARHTCEIRVAHAERAHGESKYSAMRLLNLMFDLVTCMTTTPLRLLSLVGGGMALAGFLFALFLLVLRLAFGAAWAGNGLFVLFAVLFMFSGVQLLGMGLLGEYLGRMYSDVRARPRFFIERVVRATPSALPSALQRAGFTSSSSEPSTP
References
External Links:
Resource Link
Genome ID: PA3553
Entrez Gene ID: 878472
NCBI Protein ID: 15598749
General Reference: PaperBLAST - Find papers about PA3553 and its homologs