Identification |
Name: |
isocitrate dehydrogenase |
Synonyms: |
Not Available |
Gene Name: |
idh |
Enzyme Class: |
Not Available |
Biological Properties |
General Function: |
generation of precursor metabolites and energy, oxidation-reduction process, tricarboxylic acid cycle |
Specific Function: |
enoyl-[acyl-carrier-protein] reductase (NADH) activity, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, isocitrate dehydrogenase (NADP+) activity |
Cellular Location: |
Outer Membrane Vesicle |
KEGG Pathways: |
|
KEGG Reactions: |
Not Available |
SMPDB Reactions: |
Not Available |
PseudoCyc/BioCyc Reactions: |
| D- threo-isocitrate + NADP + → 2-oxoglutarate + CO 2 + NADPH ReactionCard | | D- threo-isocitrate + NADP + = oxalosuccinate + NADPH + H +ReactionCard | | |
|
Complex Reactions: |
Not Available |
Transports: |
Not Available |
Metabolites: |
Not Available |
GO Classification: |
Function |
---|
enoyl-[acyl-carrier-protein] reductase (NADH) activity | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | isocitrate dehydrogenase (NADP+) activity | Process |
---|
generation of precursor metabolites and energy | oxidation-reduction process | tricarboxylic acid cycle |
|
Gene Properties |
Locus tag: |
PA2624 |
Strand: |
+ |
Entrez Gene ID: |
882330 |
Accession: |
NP_251314.1 |
GI: |
15597820 |
Sequence start: |
2967161 |
Sequence End: |
2969386 |
Sequence Length: |
2225 |
Gene Sequence: |
>PA2624
ATGTCCATCCGCTCGAAGATCACCTACACCTTCACCGACGAAGCACCCGCGCTCGCCACCTACTCGCTCCTCCCCATCGTCAAGGCCTTTGCCGCTTCCGCCGGCATCGACGTCGAGACCAGCGACATCTCTCTTGCAGGACGCATCCTGGCCAACTTCGCCGACCGCCTCGAAGCCGACCAGCGTATCGAAGACGACCTCGCCCGCCTGGCGGTCCTGGCCACCTCGCCCGACGCCAATATCATCAAGCTGCCCAACATCAGCGCCTCGGTGCCCCAGCTGAAAGGCGCGATCGCCGAGCTGCAGGGCCTGGGCTACAAGGTTCCCGACTTCCCGGAAGACCCGCAGACCGACGAAGAGAAAGAGGTTCGCGCACGCTACGCGAAGATCCTCGGCAGCGCCGTGAACCCGGTCCTGCGCGAAGGCAATTCCGACCGTCGCGCGCCTGCCGCAGTGAAGGCCTACGCCCGCAAGCACCCGCACTCCATGGGCAAGTGGAGCATGGCCTCGCGCTCCCACGCCGACTACATGCGCGGCGGCGACTTCTTCTCCAGCGAACAGTCCATCACCATGGCCAAGGCCGGTGACGTGCGCATCGAATTCGTCGGCAAGGACGGCAAGGTCGAGGTCAAGAAGCAACTGAGCCTGCAGGAAGGCGAAGTGCTCGACAGCATGTTCATGAGCTGCGGCAAGCTGCGCGACTTCTTCGAGAAGACCCTGCAGGACTGCAAGGAAACCGGCGTCATGTGGTCCCTGCACGTCAAGGCGACCATGATGAAGATTTCCCACCCGATCGTCTTCGGACATGCGGTGAGCGTCTACTACAAGGACGTCTTCGACAAGTGGGGCCAACTCTTCGAAGAGCTCGGCGTGAACCCGAACAACGGTATCTCCAGCGTCTACGACAAGATCAAGTCGCTGCCCGCCTCCCAGCAGGAAGAGATCCTCCACGACATCCACGAGGTGTACAGCCACCGCCCGGAAATGGCGATGGTCGACTCCGTGAAAGGCATCACCAACCTGCACATTCCGAGCGACGTCATCGTCGACGCCTCGATGCCGGCGATGATCCGCAACTCCGGCCAGATGTGGGGCAAGGACGGCAAGCAGAAAGACACCAAGGCGGTAATGCCGGAAAGCACCTACGCCCGCATCTACCAGGAGATGATCAACTTCTGCAAGACCAACGGCGCCTTCGACCCGACCACCATGGGCAGCGTGCCGAACGTCGGCCTGATGGCGCAGAAGGCCGAGGAATACGGCTCCCACGACAAGACCTTCGAAATGACCGCCGACGGCACCATGCGCGTGGTCCTGGCCGACGGCAGCGTGCTGATGCAGCACAAGGTGGAGACCGGCGACATCTGGCGCGCCTGCCAGACCAAGGACGCGCCGATCCGCGACTGGGTCAAGCTGGCCGTCACCCGCGCACGCCAGTCCGATACCCCGGCGATCTTCTGGCTGGACCCGGAGCGCGCCCACGACCGCGAACTGCGCAAGAAGGTCGAGCTGTACCTCAAGGACCACGACCTGACCGGTCTCGACATCAGCATCATGGGCTACAACGAGGCCATTCGCGTCAGCATGGAACGCCTGATCCGCGGCAAGGACACCATCTCGGTGACCGGCAACGTCCTGCGCGACTACCTGACCGACCTGTTCCCGATCATGGAACTGGGCACCTCGGCCAAGATGCTCTCCATCGTTCCGCTGATGGCGGGCGGCGGCATGTACGAAACCGGCGCCGGCGGCTCGGCACCCAAGCACGTCCAGCAACTGGTGGAAGAGAACTACCTGCGCTGGGACTCCCTGGGCGAGTTCCTGGCCCTGGCCGTGTCCCTGGAGGAAACCGGGATCAAGACCGGCAACGCCAAGGCCAAGCTGCTCGGCAAGGCGCTGGACGAAGCCACCGGCAAGCTGCTGGACAACAACAAGTCGCCGTCGCGCAAGGTCGGCGACATCGACAACCGCGGCAGCCACTTCTACCTGGCGATGTACTGGGCCCAGGCCCTGGCCGCCCAGAACGAAGACGCTGAGCTGAAAGCGCACTTCGCACCGCTGGCCAAGGCCCTGACCGAGCAGGAAGCGACCATCGTCGCCGAACTCAATGCGGTCCAGGGCAAGCCGGCCGAGATCGGCGGCTACTATCGCTCCAACCCGGAGCTGACCAGCAAGGTGATGCGCCCCAGCGCCACCTTCAACGCGGCGATCGACAGCCTGGCCTGA |
Protein Properties |
Protein Residues: |
741 |
Protein Molecular Weight: |
81.6 kDa |
Protein Theoretical pI: |
6.1 |
Hydropathicity (GRAVY score): |
-0.293 |
Charge at pH 7 (predicted): |
-8.99 |
Protein Sequence: |
>PA2624
MSIRSKITYTFTDEAPALATYSLLPIVKAFAASAGIDVETSDISLAGRILANFADRLEADQRIEDDLARLAVLATSPDANIIKLPNISASVPQLKGAIAELQGLGYKVPDFPEDPQTDEEKEVRARYAKILGSAVNPVLREGNSDRRAPAAVKAYARKHPHSMGKWSMASRSHADYMRGGDFFSSEQSITMAKAGDVRIEFVGKDGKVEVKKQLSLQEGEVLDSMFMSCGKLRDFFEKTLQDCKETGVMWSLHVKATMMKISHPIVFGHAVSVYYKDVFDKWGQLFEELGVNPNNGISSVYDKIKSLPASQQEEILHDIHEVYSHRPEMAMVDSVKGITNLHIPSDVIVDASMPAMIRNSGQMWGKDGKQKDTKAVMPESTYARIYQEMINFCKTNGAFDPTTMGSVPNVGLMAQKAEEYGSHDKTFEMTADGTMRVVLADGSVLMQHKVETGDIWRACQTKDAPIRDWVKLAVTRARQSDTPAIFWLDPERAHDRELRKKVELYLKDHDLTGLDISIMGYNEAIRVSMERLIRGKDTISVTGNVLRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVQQLVEENYLRWDSLGEFLALAVSLEETGIKTGNAKAKLLGKALDEATGKLLDNNKSPSRKVGDIDNRGSHFYLAMYWAQALAAQNEDAELKAHFAPLAKALTEQEATIVAELNAVQGKPAEIGGYYRSNPELTSKVMRPSATFNAAIDSLA |
References |
External Links: |
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General Reference: |
PaperBLAST - Find papers about PA2624 and its homologs
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