Identification
Name: isocitrate dehydrogenase
Synonyms: Not Available
Gene Name: idh
Enzyme Class: Not Available
Biological Properties
General Function: generation of precursor metabolites and energy, oxidation-reduction process, tricarboxylic acid cycle
Specific Function: enoyl-[acyl-carrier-protein] reductase (NADH) activity, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, isocitrate dehydrogenase (NADP+) activity
Cellular Location: Outer Membrane Vesicle
KEGG Pathways:
KEGG Reactions: Not Available
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
Thumb
D-threo-isocitrate + NADP+ → 2-oxoglutarate + CO2 + NADPH
ReactionCard
Thumb
D-threo-isocitrate + NADP+ = oxalosuccinate + NADPH + H+
ReactionCard
Thumb
oxalosuccinate + H+ = 2-oxoglutarate + CO2
ReactionCard
Complex Reactions: Not Available
Transports: Not Available
Metabolites: Not Available
GO Classification:
Function
enoyl-[acyl-carrier-protein] reductase (NADH) activity
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
isocitrate dehydrogenase (NADP+) activity
Process
generation of precursor metabolites and energy
oxidation-reduction process
tricarboxylic acid cycle
Gene Properties
Locus tag: PA2624
Strand: +
Entrez Gene ID: 882330
Accession: NP_251314.1
GI: 15597820
Sequence start: 2967161
Sequence End: 2969386
Sequence Length: 2225
Gene Sequence:
>PA2624
ATGTCCATCCGCTCGAAGATCACCTACACCTTCACCGACGAAGCACCCGCGCTCGCCACCTACTCGCTCCTCCCCATCGTCAAGGCCTTTGCCGCTTCCGCCGGCATCGACGTCGAGACCAGCGACATCTCTCTTGCAGGACGCATCCTGGCCAACTTCGCCGACCGCCTCGAAGCCGACCAGCGTATCGAAGACGACCTCGCCCGCCTGGCGGTCCTGGCCACCTCGCCCGACGCCAATATCATCAAGCTGCCCAACATCAGCGCCTCGGTGCCCCAGCTGAAAGGCGCGATCGCCGAGCTGCAGGGCCTGGGCTACAAGGTTCCCGACTTCCCGGAAGACCCGCAGACCGACGAAGAGAAAGAGGTTCGCGCACGCTACGCGAAGATCCTCGGCAGCGCCGTGAACCCGGTCCTGCGCGAAGGCAATTCCGACCGTCGCGCGCCTGCCGCAGTGAAGGCCTACGCCCGCAAGCACCCGCACTCCATGGGCAAGTGGAGCATGGCCTCGCGCTCCCACGCCGACTACATGCGCGGCGGCGACTTCTTCTCCAGCGAACAGTCCATCACCATGGCCAAGGCCGGTGACGTGCGCATCGAATTCGTCGGCAAGGACGGCAAGGTCGAGGTCAAGAAGCAACTGAGCCTGCAGGAAGGCGAAGTGCTCGACAGCATGTTCATGAGCTGCGGCAAGCTGCGCGACTTCTTCGAGAAGACCCTGCAGGACTGCAAGGAAACCGGCGTCATGTGGTCCCTGCACGTCAAGGCGACCATGATGAAGATTTCCCACCCGATCGTCTTCGGACATGCGGTGAGCGTCTACTACAAGGACGTCTTCGACAAGTGGGGCCAACTCTTCGAAGAGCTCGGCGTGAACCCGAACAACGGTATCTCCAGCGTCTACGACAAGATCAAGTCGCTGCCCGCCTCCCAGCAGGAAGAGATCCTCCACGACATCCACGAGGTGTACAGCCACCGCCCGGAAATGGCGATGGTCGACTCCGTGAAAGGCATCACCAACCTGCACATTCCGAGCGACGTCATCGTCGACGCCTCGATGCCGGCGATGATCCGCAACTCCGGCCAGATGTGGGGCAAGGACGGCAAGCAGAAAGACACCAAGGCGGTAATGCCGGAAAGCACCTACGCCCGCATCTACCAGGAGATGATCAACTTCTGCAAGACCAACGGCGCCTTCGACCCGACCACCATGGGCAGCGTGCCGAACGTCGGCCTGATGGCGCAGAAGGCCGAGGAATACGGCTCCCACGACAAGACCTTCGAAATGACCGCCGACGGCACCATGCGCGTGGTCCTGGCCGACGGCAGCGTGCTGATGCAGCACAAGGTGGAGACCGGCGACATCTGGCGCGCCTGCCAGACCAAGGACGCGCCGATCCGCGACTGGGTCAAGCTGGCCGTCACCCGCGCACGCCAGTCCGATACCCCGGCGATCTTCTGGCTGGACCCGGAGCGCGCCCACGACCGCGAACTGCGCAAGAAGGTCGAGCTGTACCTCAAGGACCACGACCTGACCGGTCTCGACATCAGCATCATGGGCTACAACGAGGCCATTCGCGTCAGCATGGAACGCCTGATCCGCGGCAAGGACACCATCTCGGTGACCGGCAACGTCCTGCGCGACTACCTGACCGACCTGTTCCCGATCATGGAACTGGGCACCTCGGCCAAGATGCTCTCCATCGTTCCGCTGATGGCGGGCGGCGGCATGTACGAAACCGGCGCCGGCGGCTCGGCACCCAAGCACGTCCAGCAACTGGTGGAAGAGAACTACCTGCGCTGGGACTCCCTGGGCGAGTTCCTGGCCCTGGCCGTGTCCCTGGAGGAAACCGGGATCAAGACCGGCAACGCCAAGGCCAAGCTGCTCGGCAAGGCGCTGGACGAAGCCACCGGCAAGCTGCTGGACAACAACAAGTCGCCGTCGCGCAAGGTCGGCGACATCGACAACCGCGGCAGCCACTTCTACCTGGCGATGTACTGGGCCCAGGCCCTGGCCGCCCAGAACGAAGACGCTGAGCTGAAAGCGCACTTCGCACCGCTGGCCAAGGCCCTGACCGAGCAGGAAGCGACCATCGTCGCCGAACTCAATGCGGTCCAGGGCAAGCCGGCCGAGATCGGCGGCTACTATCGCTCCAACCCGGAGCTGACCAGCAAGGTGATGCGCCCCAGCGCCACCTTCAACGCGGCGATCGACAGCCTGGCCTGA
Protein Properties
Protein Residues: 741
Protein Molecular Weight: 81.6 kDa
Protein Theoretical pI: 6.1
Hydropathicity (GRAVY score): -0.293
Charge at pH 7 (predicted): -8.99
Protein Sequence:
>PA2624
MSIRSKITYTFTDEAPALATYSLLPIVKAFAASAGIDVETSDISLAGRILANFADRLEADQRIEDDLARLAVLATSPDANIIKLPNISASVPQLKGAIAELQGLGYKVPDFPEDPQTDEEKEVRARYAKILGSAVNPVLREGNSDRRAPAAVKAYARKHPHSMGKWSMASRSHADYMRGGDFFSSEQSITMAKAGDVRIEFVGKDGKVEVKKQLSLQEGEVLDSMFMSCGKLRDFFEKTLQDCKETGVMWSLHVKATMMKISHPIVFGHAVSVYYKDVFDKWGQLFEELGVNPNNGISSVYDKIKSLPASQQEEILHDIHEVYSHRPEMAMVDSVKGITNLHIPSDVIVDASMPAMIRNSGQMWGKDGKQKDTKAVMPESTYARIYQEMINFCKTNGAFDPTTMGSVPNVGLMAQKAEEYGSHDKTFEMTADGTMRVVLADGSVLMQHKVETGDIWRACQTKDAPIRDWVKLAVTRARQSDTPAIFWLDPERAHDRELRKKVELYLKDHDLTGLDISIMGYNEAIRVSMERLIRGKDTISVTGNVLRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVQQLVEENYLRWDSLGEFLALAVSLEETGIKTGNAKAKLLGKALDEATGKLLDNNKSPSRKVGDIDNRGSHFYLAMYWAQALAAQNEDAELKAHFAPLAKALTEQEATIVAELNAVQGKPAEIGGYYRSNPELTSKVMRPSATFNAAIDSLA
References
External Links:
Resource Link
Genome ID: PA2624
Entrez Gene ID: 882330
NCBI Protein ID: 15597820
General Reference: PaperBLAST - Find papers about PA2624 and its homologs