Identification
Name: DNA polymerase II
Synonyms:
  • Pol II
Gene Name: polB
Enzyme Class:
Biological Properties
General Function: Involved in nucleotide binding
Specific Function: Thought to be involved in DNA repair and/or mutagenesis
Cellular Location: Cytoplasmic
KEGG Pathways:
KEGG Reactions:
Deoxynucleoside triphosphate+DNAThumb
Deoxynucleoside triphosphate + DNA ↔ Pyrophosphate
ReactionCard
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
DNAn ? a nucleoside monophosphate
DNAn ? a nucleoside monophosphate
ReactionCard
Complex Reactions:
Deoxynucleoside triphosphate+DNA(n)Thumb+DNA(n+1)
Deoxynucleoside triphosphate + DNA(n) → Pyrophosphate + DNA(n+1)
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000633PyrophosphateMetaboCard
GO Classification:
Function
binding
catalytic activity
DNA binding
DNA polymerase activity
DNA-directed DNA polymerase activity
nucleic acid binding
nucleotide binding
nucleotidyltransferase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
Process
cellular macromolecule metabolic process
cellular nitrogen compound metabolic process
DNA metabolic process
DNA replication
macromolecule metabolic process
metabolic process
nitrogen compound metabolic process
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
Gene Properties
Locus tag: PA1886
Strand: +
Entrez Gene ID: 878669
Accession: NP_250577.1
GI: 15597083
Sequence start: 2054911
Sequence End: 2057274
Sequence Length: 2363
Gene Sequence:
>PA1886
GTGGAGTTACTGCAAGGGTTCGTCCTGACCCGGCACTGGCGCGATACGCCGGCCGGCACGGAAGTCGCGTTCTGGCTGGCGACCGAGCAGGGCCCGCGGCAGGTGCGGCTGCCGCCGCAGCCGTCGGTGGCGTTCGTCCTCGCCGAGCAGCGCGGGCGCGTCGAGTCCCTGCTCGCCGGGGAGACTGGCGCCGAGCTGCGGCCGCTGGCGCTGCGCGACTTCCAGCAGCGGCCGGTGCTTGGCCTGTACTGCCAGCAGCATCGCCAACTGATGAATCTGGAGAAACGCTTGCGCCAGGCCGGCGTCGAGGTGTTCGAGGCCGATATCCGGCCGCCGGAGCGCTACCTGATGGAGCGCTTCATCACCGCGCCGGTCAGCCTGGAGGCGAGTGTCGAGGCTGACGGCAGCCTGCTCGCCCGGCGCCTGAAGCCGGCTCCGGACTATCGCCCGCGCCTGCGCCTGGTGTCGCTGGACATCGAGACCAACGCCCGCGGCGATCTCTACTCCATCGCCCTGGAAGGCTGCGACCAGCGCCAGGTATACATGCTCGGCCCGGCCAACGGCGATGCCGCGGCCGTGGATTTCCGCCTCGACTATTGCGACAGCCGTGCCGGGCTGCTGGAACGTCTCAACCAGTGGCTGGCCGAGCACGATCCCGACGCCATCATCGGCTGGAACCTGGTGCAGTTCGACCTGCGCGTCCTGCATGAGCATGCCCAGCGCCTGAAGGTGCCGCTGCGCCTGGGGCGTGGCGGCGACGAAATGGGCTGGCGCGAGCACGGCAGCCGCAACAACCACTTTTTCGCCGCGGCGGCCGGCCGCCTGATCATCGATGGCATCGAGGCGCTGCGCTCGGCGACCTGGAGCTTCCCCTCGTTCAGCCTGGAGAACGTCGCCCGGACCCTGCTCGGCGAAGGCAAGGCGATCGACAATCCGTACCAGCGGATGGACGAGATCGATCGCATGTTCGCCGAGGACAAGCCGGCCCTCGCGCACTACAACCTGAAGGACTGCGAATTGGTGACGCGGATCTTCGCCCGTACCGAACTGCTCGACTTCCTCCTCGAACGGGCCACCGTCACCGGCCTGCCGGCGGACCGCAGCGGCGGCTCGGTGGCGGCCTTCACCCACCTGTACATGCCGTTGATGCACCGCGCCGGCTTCGTCGCCCCGAACCTCGGCGAGAAGCGTCCGGAAGCCAGTCCCGGCGGCTTCGTCATGGACTCGCGGCCGGGCCTCTACGAATCGGTGCTGGTGCTCGACTACAAGAGCCTGTATCCGTCGATCATCCGTACCTTCCTGATCGATCCGGTCGGCCTGGTGGAAGGCCTGCGCCAGCCGGACGACGAGCACTCGGTGGAAGGCTTTCGCGGCGCCCGCTTCTCGCGTACCCGGCATTGCCTGCCGGCCATCGTCGCACGGGTCTGGGAGGGCCGCGAGGCGGCCAAGCGCGAACGCAACCAGCCGCTCTCGCAGGCGTTGAAGATCATCATGAACGCCTTCTACGGGGTGCTGGGTTCCAGCGGCTGCCGCTTCTTCGACCCGCGCCTGGCCTCGTCCATCACCCTGCGCGGGCATCGGATCATGCGCCGTACCCGCGAGCTGATCGAGGCCGAGGGCTATACGGTGATCTATGGCGATACCGACTCCACCTTCGTCTGGCTCGGCAGCCCCCGCGCCGAGGAGGAGGCCGCGGCCATCGGCCGGGCGCTGGTGGCGCGGGTCAACGACTGGTGGCGCGAGCACCTGAAAGAAGAATTCGGCCTCGACAGCGCCCTCGAGCTGCAATTCGAGACCCATTACCGGCGTTTTCTCATGCCCACCGTGCGCGGCGCCGAGGAGGGCAGCAAGAAACGCTACGCCGGCCTGGTGCGCCGCGCCGACGGTGGCGAGGAGATGGTCTTCAAGGGCCTGGAGACCGTGCGCACCGACTGGTCGCCGCTGGCCCAGCGCTTCCAGCAGGAACTCTACCTGCGCATCTTCAATCGCCAGCCCTACCAGGACTACGTGCGCGATTACGTACGACGGACCCTGGCCGGCGAGCTGGACGACCTGCTGGTCTACCGCAAGCGCCTGCGCCGGCGCCTCGACGATTACCAGCGCAACGTGCCGCCGCATGTGCGCGCGGCGCGCATCGCCGACGACTACAACCTCGAGCGCGGGCGCCCGCGGCAGTACCAGAGCGGCGGCTGGATCAGCTACGTGATCAGCGTCGCCGGTCCCGAGCCGCTCGAGGCGCGGCGTTCGGCCATCGACTACGAGCACTACGTGGGCAAGCAGTTGCAGCCGGTGGCCGACGCCATCCTGCCGTTCGTCGGCGATGATTTCGCCACTTTGGTCGACCGGCAGATGGCACTATTCTGA
Protein Properties
Protein Residues: 787
Protein Molecular Weight: 89.7 kDa
Protein Theoretical pI: 7.29
Hydropathicity (GRAVY score): -0.38
Charge at pH 7 (predicted): 1.97
Protein Sequence:
>PA1886
MELLQGFVLTRHWRDTPAGTEVAFWLATEQGPRQVRLPPQPSVAFVLAEQRGRVESLLAGETGAELRPLALRDFQQRPVLGLYCQQHRQLMNLEKRLRQAGVEVFEADIRPPERYLMERFITAPVSLEASVEADGSLLARRLKPAPDYRPRLRLVSLDIETNARGDLYSIALEGCDQRQVYMLGPANGDAAAVDFRLDYCDSRAGLLERLNQWLAEHDPDAIIGWNLVQFDLRVLHEHAQRLKVPLRLGRGGDEMGWREHGSRNNHFFAAAAGRLIIDGIEALRSATWSFPSFSLENVARTLLGEGKAIDNPYQRMDEIDRMFAEDKPALAHYNLKDCELVTRIFARTELLDFLLERATVTGLPADRSGGSVAAFTHLYMPLMHRAGFVAPNLGEKRPEASPGGFVMDSRPGLYESVLVLDYKSLYPSIIRTFLIDPVGLVEGLRQPDDEHSVEGFRGARFSRTRHCLPAIVARVWEGREAAKRERNQPLSQALKIIMNAFYGVLGSSGCRFFDPRLASSITLRGHRIMRRTRELIEAEGYTVIYGDTDSTFVWLGSPRAEEEAAAIGRALVARVNDWWREHLKEEFGLDSALELQFETHYRRFLMPTVRGAEEGSKKRYAGLVRRADGGEEMVFKGLETVRTDWSPLAQRFQQELYLRIFNRQPYQDYVRDYVRRTLAGELDDLLVYRKRLRRRLDDYQRNVPPHVRAARIADDYNLERGRPRQYQSGGWISYVISVAGPEPLEARRSAIDYEHYVGKQLQPVADAILPFVGDDFATLVDRQMALF
References
External Links:
Resource Link
Genome ID: PA1886
Entrez Gene ID: 878669
NCBI Protein ID: 15597083
General Reference: PaperBLAST - Find papers about PA1886 and its homologs