Identification |
Name: |
DNA polymerase II |
Synonyms: |
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Gene Name: |
polB |
Enzyme Class: |
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Biological Properties |
General Function: |
Involved in nucleotide binding |
Specific Function: |
Thought to be involved in DNA repair and/or mutagenesis |
Cellular Location: |
Cytoplasmic |
KEGG Pathways: |
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KEGG Reactions: |
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Deoxynucleoside triphosphate | + | DNA | ↔ | |
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SMPDB Reactions: |
Not Available |
PseudoCyc/BioCyc Reactions: |
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DNAn | ? | a nucleoside monophosphate |
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Complex Reactions: |
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Deoxynucleoside triphosphate | + | DNA(n) | → | | + | DNA(n+1) |
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Transports: |
Not Available |
Metabolites: |
PAMDB ID | Name | View |
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PAMDB000633 | Pyrophosphate | MetaboCard |
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GO Classification: |
Function |
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binding | catalytic activity | DNA binding | DNA polymerase activity | DNA-directed DNA polymerase activity | nucleic acid binding | nucleotide binding | nucleotidyltransferase activity | transferase activity | transferase activity, transferring phosphorus-containing groups | Process |
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cellular macromolecule metabolic process | cellular nitrogen compound metabolic process | DNA metabolic process | DNA replication | macromolecule metabolic process | metabolic process | nitrogen compound metabolic process | nucleobase, nucleoside, nucleotide and nucleic acid metabolic process |
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Gene Properties |
Locus tag: |
PA1886 |
Strand: |
+ |
Entrez Gene ID: |
878669 |
Accession: |
NP_250577.1 |
GI: |
15597083 |
Sequence start: |
2054911 |
Sequence End: |
2057274 |
Sequence Length: |
2363 |
Gene Sequence: |
>PA1886
GTGGAGTTACTGCAAGGGTTCGTCCTGACCCGGCACTGGCGCGATACGCCGGCCGGCACGGAAGTCGCGTTCTGGCTGGCGACCGAGCAGGGCCCGCGGCAGGTGCGGCTGCCGCCGCAGCCGTCGGTGGCGTTCGTCCTCGCCGAGCAGCGCGGGCGCGTCGAGTCCCTGCTCGCCGGGGAGACTGGCGCCGAGCTGCGGCCGCTGGCGCTGCGCGACTTCCAGCAGCGGCCGGTGCTTGGCCTGTACTGCCAGCAGCATCGCCAACTGATGAATCTGGAGAAACGCTTGCGCCAGGCCGGCGTCGAGGTGTTCGAGGCCGATATCCGGCCGCCGGAGCGCTACCTGATGGAGCGCTTCATCACCGCGCCGGTCAGCCTGGAGGCGAGTGTCGAGGCTGACGGCAGCCTGCTCGCCCGGCGCCTGAAGCCGGCTCCGGACTATCGCCCGCGCCTGCGCCTGGTGTCGCTGGACATCGAGACCAACGCCCGCGGCGATCTCTACTCCATCGCCCTGGAAGGCTGCGACCAGCGCCAGGTATACATGCTCGGCCCGGCCAACGGCGATGCCGCGGCCGTGGATTTCCGCCTCGACTATTGCGACAGCCGTGCCGGGCTGCTGGAACGTCTCAACCAGTGGCTGGCCGAGCACGATCCCGACGCCATCATCGGCTGGAACCTGGTGCAGTTCGACCTGCGCGTCCTGCATGAGCATGCCCAGCGCCTGAAGGTGCCGCTGCGCCTGGGGCGTGGCGGCGACGAAATGGGCTGGCGCGAGCACGGCAGCCGCAACAACCACTTTTTCGCCGCGGCGGCCGGCCGCCTGATCATCGATGGCATCGAGGCGCTGCGCTCGGCGACCTGGAGCTTCCCCTCGTTCAGCCTGGAGAACGTCGCCCGGACCCTGCTCGGCGAAGGCAAGGCGATCGACAATCCGTACCAGCGGATGGACGAGATCGATCGCATGTTCGCCGAGGACAAGCCGGCCCTCGCGCACTACAACCTGAAGGACTGCGAATTGGTGACGCGGATCTTCGCCCGTACCGAACTGCTCGACTTCCTCCTCGAACGGGCCACCGTCACCGGCCTGCCGGCGGACCGCAGCGGCGGCTCGGTGGCGGCCTTCACCCACCTGTACATGCCGTTGATGCACCGCGCCGGCTTCGTCGCCCCGAACCTCGGCGAGAAGCGTCCGGAAGCCAGTCCCGGCGGCTTCGTCATGGACTCGCGGCCGGGCCTCTACGAATCGGTGCTGGTGCTCGACTACAAGAGCCTGTATCCGTCGATCATCCGTACCTTCCTGATCGATCCGGTCGGCCTGGTGGAAGGCCTGCGCCAGCCGGACGACGAGCACTCGGTGGAAGGCTTTCGCGGCGCCCGCTTCTCGCGTACCCGGCATTGCCTGCCGGCCATCGTCGCACGGGTCTGGGAGGGCCGCGAGGCGGCCAAGCGCGAACGCAACCAGCCGCTCTCGCAGGCGTTGAAGATCATCATGAACGCCTTCTACGGGGTGCTGGGTTCCAGCGGCTGCCGCTTCTTCGACCCGCGCCTGGCCTCGTCCATCACCCTGCGCGGGCATCGGATCATGCGCCGTACCCGCGAGCTGATCGAGGCCGAGGGCTATACGGTGATCTATGGCGATACCGACTCCACCTTCGTCTGGCTCGGCAGCCCCCGCGCCGAGGAGGAGGCCGCGGCCATCGGCCGGGCGCTGGTGGCGCGGGTCAACGACTGGTGGCGCGAGCACCTGAAAGAAGAATTCGGCCTCGACAGCGCCCTCGAGCTGCAATTCGAGACCCATTACCGGCGTTTTCTCATGCCCACCGTGCGCGGCGCCGAGGAGGGCAGCAAGAAACGCTACGCCGGCCTGGTGCGCCGCGCCGACGGTGGCGAGGAGATGGTCTTCAAGGGCCTGGAGACCGTGCGCACCGACTGGTCGCCGCTGGCCCAGCGCTTCCAGCAGGAACTCTACCTGCGCATCTTCAATCGCCAGCCCTACCAGGACTACGTGCGCGATTACGTACGACGGACCCTGGCCGGCGAGCTGGACGACCTGCTGGTCTACCGCAAGCGCCTGCGCCGGCGCCTCGACGATTACCAGCGCAACGTGCCGCCGCATGTGCGCGCGGCGCGCATCGCCGACGACTACAACCTCGAGCGCGGGCGCCCGCGGCAGTACCAGAGCGGCGGCTGGATCAGCTACGTGATCAGCGTCGCCGGTCCCGAGCCGCTCGAGGCGCGGCGTTCGGCCATCGACTACGAGCACTACGTGGGCAAGCAGTTGCAGCCGGTGGCCGACGCCATCCTGCCGTTCGTCGGCGATGATTTCGCCACTTTGGTCGACCGGCAGATGGCACTATTCTGA |
Protein Properties |
Protein Residues: |
787 |
Protein Molecular Weight: |
89.7 kDa |
Protein Theoretical pI: |
7.29 |
Hydropathicity (GRAVY score): |
-0.38 |
Charge at pH 7 (predicted): |
1.97 |
Protein Sequence: |
>PA1886
MELLQGFVLTRHWRDTPAGTEVAFWLATEQGPRQVRLPPQPSVAFVLAEQRGRVESLLAGETGAELRPLALRDFQQRPVLGLYCQQHRQLMNLEKRLRQAGVEVFEADIRPPERYLMERFITAPVSLEASVEADGSLLARRLKPAPDYRPRLRLVSLDIETNARGDLYSIALEGCDQRQVYMLGPANGDAAAVDFRLDYCDSRAGLLERLNQWLAEHDPDAIIGWNLVQFDLRVLHEHAQRLKVPLRLGRGGDEMGWREHGSRNNHFFAAAAGRLIIDGIEALRSATWSFPSFSLENVARTLLGEGKAIDNPYQRMDEIDRMFAEDKPALAHYNLKDCELVTRIFARTELLDFLLERATVTGLPADRSGGSVAAFTHLYMPLMHRAGFVAPNLGEKRPEASPGGFVMDSRPGLYESVLVLDYKSLYPSIIRTFLIDPVGLVEGLRQPDDEHSVEGFRGARFSRTRHCLPAIVARVWEGREAAKRERNQPLSQALKIIMNAFYGVLGSSGCRFFDPRLASSITLRGHRIMRRTRELIEAEGYTVIYGDTDSTFVWLGSPRAEEEAAAIGRALVARVNDWWREHLKEEFGLDSALELQFETHYRRFLMPTVRGAEEGSKKRYAGLVRRADGGEEMVFKGLETVRTDWSPLAQRFQQELYLRIFNRQPYQDYVRDYVRRTLAGELDDLLVYRKRLRRRLDDYQRNVPPHVRAARIADDYNLERGRPRQYQSGGWISYVISVAGPEPLEARRSAIDYEHYVGKQLQPVADAILPFVGDDFATLVDRQMALF |
References |
External Links: |
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General Reference: |
PaperBLAST - Find papers about PA1886 and its homologs
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